ROXITHROMYCIN+AMBROXOL is a respiratory combination medication primarily used to treat cough associated with respiratory disorders like asthma and chronic obstructive pulmonary diseases (COPD). Asthma is a breathing problem in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Coughing occurs as a reflex action in the throat when there is mucus or any other foreign irritant in it.
The ROXITHROMYCIN+AMBROXOL consists of two medicines: Roxithromycin (antibiotic) and Ambroxol (dilutes viscous cough). Roxithromycin comes into the category of antibiotic medicines that stop bacterial growth by inhibiting the protein synthesis process required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. It is a bacteriostatic antibiotic, i.e. it stops bacteria's growth but does not necessarily kill them. On the other hand, Ambroxol is an 'expectorant' (promotes the secretion of sputum/cough) and 'mucolytic agent' (makes sputum less viscous) to make breathing easier in asthma, and COPD patients who have difficulty in breathing.
Take ROXITHROMYCIN+AMBROXOL preferably with food to avoid stomach upset and swallow whole with a glass of water. Do not crush, chew, or break it. Your doctor will recommend how often you take ROXITHROMYCIN+AMBROXOL based on your medical condition. Some people may experience nausea, vomiting, diarrhoea, taste disturbance, stomach pain, and allergic reaction. Most of these side effects of ROXITHROMYCIN+AMBROXOL do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Before using ROXITHROMYCIN+AMBROXOL tell your doctor if you ever had an allergy to ROXITHROMYCIN+AMBROXOL, have kidney problems, liver problems, heart disease, peptic or duodenal ulcers. Please do not drink alcohol with ROXITHROMYCIN+AMBROXOL as it may increase the unpleasant side effects like drowsiness, and dizziness. ROXITHROMYCIN+AMBROXOL is not recommended in the first three months of pregnancy, and also breastfeeding women should not take it. Do not consume alcohol as it may cause excessive drowsiness when taken along with ROXITHROMYCIN+AMBROXOL.
Respiratory tract infection
ROXITHROMYCIN+AMBROXOL consists of two medicines, namely: Roxithromycin (antibiotic) and Ambroxol (dilutes viscous cough). Roxithromycin comes into the category of antibiotic medicines that stop bacterial growth by inhibiting the protein synthesis process required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. It is a bacteriostatic antibiotic, i.e. it stops bacteria's growth but does not necessarily kill them. On the other hand, Ambroxol is an 'expectorant' (promotes the secretion of sputum/cough) and 'mucolytic agent' (makes sputum less viscous) to make breathing easier in asthma, and COPD patients who have difficulty in breathing.
Let your doctor know if you have any allergic reactions to medicines. Please inform your doctor if you have any history of heart, liver, kidney diseases, peptic or duodenal ulcers. Also, take ROXITHROMYCIN+AMBROXOL with caution if you have asthma or suffer from a severe asthma attack, have had a cough for a long time. Do not take ROXITHROMYCIN+AMBROXOL if you are already taking medicines like ergot alkaloids (anti-migraine medicine), terfenadine or astemizole (anti-allergy medicine), cisapride (stomach medicine), or pimozide (anti-psychotic medication). Take antacids 2 hours before or after taking ROXITHROMYCIN+AMBROXOL. Do not take ROXITHROMYCIN+AMBROXOL, especially during the first three months of pregnancy. ROXITHROMYCIN+AMBROXOL may be excreted in breast milk, so do not use ROXITHROMYCIN+AMBROXOL while breast-feeding. Do not take ROXITHROMYCIN+AMBROXOL without informing your doctor for more than ten days.
Drug-Drug Interactions: ROXITHROMYCIN+AMBROXOL may interact with terfenadine or astemizole (anti-allergy medicine), cisapride (stomach medicine), pimozide (an antipsychotic medicine), statin (a cholesterol-lowering medicine), theophylline (an asthma medicine), bromocriptine (medicine for Parkinson's disease), ergotamine or dihydroergotamine (anti-migraine medicine), and codeine.
Drug-Food Interactions: No known interaction found/established.
Drug-Disease Interactions: Inform your doctor if you have asthma or suffer from serious asthma attacks, have peptic or duodenal ulcers, impaired hepatic function, and heart disease.
Avoid consumption of alcohol while taking ROXITHROMYCIN+AMBROXOL.
Do not take ROXITHROMYCIN+AMBROXOL, especially during the first 3 months of pregnancy.
ROXITHROMYCIN+AMBROXOL may be excreted in breast milk, so do not use ROXITHROMYCIN+AMBROXOL while breast-feeding.
Do not drive or operate machinery if you experience drowsiness, dizziness. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.
ROXITHROMYCIN+AMBROXOL should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing ROXITHROMYCIN+AMBROXOL.
ROXITHROMYCIN+AMBROXOL should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing ROXITHROMYCIN+AMBROXOL.
ROXITHROMYCIN+AMBROXOL can be given to children if prescribed by a child specialist.
Asthma: It is a breathing problem in which airways narrow, swell, and produce extra mucus (cough), leading to difficulty breathing.
Chronic obstructive pulmonary diseases (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes).