SODIUM VALPROATE+VALPROMIDE belongs to a class of drugs called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, SODIUM VALPROATE+VALPROMIDE also treats bipolar disorder and prevents migraine headaches. Epilepsy is a disorder in which there is a sudden, uncontrolled disturbance in nerve cells' electrical activity in the brain, resulting in recurrent seizures (fits), sometimes leading to an unconscious state.
SODIUM VALPROATE+VALPROMIDE is a combination of two anticonvulsants, namely: Sodium valproate and valpromide. SODIUM VALPROATE+VALPROMIDE works by increasing GABA release (a chemical messenger that acts as a nerve-calming agent) in the brain by acting on GABA receptors. Thereby, SODIUM VALPROATE+VALPROMIDE prevents fits by stabilizing the electrical activity of nerve cells in the brain. Off-label use of SODIUM VALPROATE+VALPROMIDE includes in the treatment of bipolar disorder.
Take SODIUM VALPROATE+VALPROMIDE as prescribed by your doctor. You are advised to take SODIUM VALPROATE+VALPROMIDE for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects of SODIUM VALPROATE+VALPROMIDE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Avoid taking SODIUM VALPROATE+VALPROMIDE during pregnancy as it is a category D pregnancy drug and may harm the unborn baby. Please consult your doctor before taking SODIUM VALPROATE+VALPROMIDE if you are pregnant, planning for pregnancy or breastfeeding. SODIUM VALPROATE+VALPROMIDE should be used with caution in children below 12 years of age. Contact your doctor if your daughter gets her first period during treatment with SODIUM VALPROATE+VALPROMIDE. Avoid alcohol consumption with SODIUM VALPROATE+VALPROMIDE as it may increase drowsiness or tiredness. Drive only if you are alert, as SODIUM VALPROATE+VALPROMIDE may cause dizziness, drowsiness or tiredness.
Epilepsy, Bipolar disorder, Migraine
SODIUM VALPROATE+VALPROMIDE is a combination of two anticonvulsants, namely: Sodium valproate and valpromide, used to treat epilepsy, and bipolar disorder and also prevent migraine headaches. SODIUM VALPROATE+VALPROMIDE decreases the excessive and abnormal nerve cell activity in the brain. SODIUM VALPROATE+VALPROMIDE works by increasing the release of GABA (a chemical messenger that acts as a nerve-calming agent) in the brain by acting on GABA receptors. Thereby, SODIUM VALPROATE+VALPROMIDE prevents fits by stabilizing the electrical activity of nerve cells in the brain.
If you are known to be allergic to SODIUM VALPROATE+VALPROMIDE or any other medicines, please tell your doctor. Avoid taking SODIUM VALPROATE+VALPROMIDE during pregnancy as it is a category D pregnancy drug and may cause harm to the unborn baby. Please consult your doctor before taking SODIUM VALPROATE+VALPROMIDE if you are pregnant, planning for pregnancy or breastfeeding. SODIUM VALPROATE+VALPROMIDE should be used with caution in children. Contact your doctor if your daughter gets her first period during treatment with SODIUM VALPROATE+VALPROMIDE. If you have depression, liver, kidney or pancreas problems, urea cycle disorders, Alpers-Huttenlocher syndrome (a genetic problem), porphyria (a disorder in the formation of red blood pigment) or thrombocytopenia (low levels of platelets), inform your doctor before taking SODIUM VALPROATE+VALPROMIDE. Avoid alcohol consumption with SODIUM VALPROATE+VALPROMIDE as it may increase drowsiness or tiredness. Drive only if you are alert, as SODIUM VALPROATE+VALPROMIDE may cause dizziness, drowsiness or tiredness.
Drug-Drug Interaction: SODIUM VALPROATE+VALPROMIDE may have interaction with pain killers (aspirin), anticonvulsants (phenobarbital, primidone, phenytoin, carbamazepine, topiramate, acetazolamide, lamotrigine, felbamate), blood thinner (warfarin), anti-HIV drugs (zidovudine, lopinavir, ritonavir), antidepressants (moclobemide, selegiline, linezolid, amitriptyline, sertraline), antipsychotics (quetiapine, olanzapine, risperidone), calcium channel blocker (nimodipine), anaesthetic (propofol), hormones (oestrogen, levonorgestrel), anti-malarial (mefloquine, chloroquine), antacid (cimetidine), antibiotics (imipenem, meropenem, rifampicin, erythromycin), high cholesterol-lowering drug (cholestyramine), benzodiazepine (clonazepam, diazepam).
Drug-Food Interaction: SODIUM VALPROATE+VALPROMIDE may interact with alcohol. Therefore, avoid alcohol consumption while taking SODIUM VALPROATE+VALPROMIDE as it may increase drowsiness or tiredness.
Drug-Disease Interaction: If you have depression, liver, kidney or pancreas problems, urea cycle disorders, Alpers-Huttenlocher syndrome (a genetic problem), porphyria (a disorder in the formation of red blood pigment) or thrombocytopenia (low levels of platelets), inform your doctor before taking SODIUM VALPROATE+VALPROMIDE.
Avoid consumption of alcohol with SODIUM VALPROATE+VALPROMIDE as it may increase drowsiness or tiredness.
SODIUM VALPROATE+VALPROMIDE is a Category D pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy before taking SODIUM VALPROATE+VALPROMIDE.
Small amounts of SODIUM VALPROATE+VALPROMIDE may be excreted in human milk. Please consult a doctor if you are breastfeeding before taking SODIUM VALPROATE+VALPROMIDE.
SODIUM VALPROATE+VALPROMIDE may cause dizziness, drowsiness or tiredness in some people. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking SODIUM VALPROATE+VALPROMIDE.
Avoid taking SODIUM VALPROATE+VALPROMIDE if you have liver problems, or your family have a history of liver problems. Please consult your doctor if you have any concerns regarding this.
Take SODIUM VALPROATE+VALPROMIDE with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
SODIUM VALPROATE+VALPROMIDE should be used in children only if prescribed by a doctor.
Epilepsy: It is a sudden rush of electricity in the brain. It is a disorder of the nervous system in which there is a sudden, uncontrolled disturbance in the electrical activity of nerve cells in the brain resulting in recurrent seizures (fits), sometimes leading to an unconscious state. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury or stroke.
Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows.