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About TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR

TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR belongs to a group of medicines called antiretroviral agents indicated for the treatment of HIV infection. It may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer.

TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR contains Tenofovir disoproxil fumarate, Emtricitabine, Atazanavir and Ritonavir. They work by decreasing the amount of HIV in the blood and increasing the number of immune cells that help fight infections in the body. Thus, TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR helps treat HIV infection.

In some cases, TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR may cause side effects such as headache, nausea, vomiting, diarrhoea, and stomach pain. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Consult the doctor if you are pregnant or planning for pregnancy. Breastfeeding is not recommended due to the potential for HIV transmission. Keep the doctor informed about your health condition and medicines you are taking to prevent any side effects/interactions.

Medicinal Benefits

TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR is used to treat HIV infection. It contains Tenofovir disoproxil fumarate (nucleoside reverse transcriptase inhibitors), Emtricitabine (nucleoside reverse transcriptase inhibitors), Atazanavir (protease inhibitors) and Ritonavir (protease inhibitors). Tenofovir disoproxil fumarate and Emtricitabine reduce the amount of viral load in the body by preventing the virus from multiplying. Atazanavir and Ritonavir inhibit the protease enzyme the viral cells require for reproduction.  Together, TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR helps treat HIV infection.

Directions for Use

Swallow the medicine as a whole with water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR

  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Headache

In-Depth Precautions and Warning

Drug Warnings

Do not take TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR if you are allergic to any of its components. Inform the doctor if you have/had hepatitis B or C infection, liver, kidney or heart problems, diabetes, haemophilia (bleeding disorder) or if you are allergic to sulpha drugs. Consult the doctor if you are pregnant or planning for pregnancy. Women with HIV should not breastfeed as the virus may pass to the baby through breast milk. Let the doctor know if you take other medicines, including supplements or herbal products.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking lipid-lowering agents (rosuvastatin, atorvastatin), anti-coagulant (apixaban), anti-HIV (etravirine, dolutegravir/lamivudine), analgesic (oxycodone), anti-anxiety (alprazolam), or anti-psychotics (quetiapine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have liver or kidney problems, haemophilia, diabetes, hyperlipidaemia, hepatitis, heart block or nephrolithiasis (kidney stones).

Drug-Drug Interactions Checker List:

  • ROSUVASTATIN
  • ATORVASTATIN
  • APIXABAN
  • ETRAVIRINE
  • DOLUTEGRAVIR+LAMIVUDINE
  • OXYCODONE
  • ALPRAZOLAM
  • QUETIAPINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid alcohol consumption during treatment with TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR.

    • Safety Warning

      Pregnancy

      caution

      Please consult the doctor if you are pregnant. TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR should be used during pregnancy only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      unsafe

      Breastfeeding is not recommended due to the potential for HIV transmission.

    • Safety Warning

      Driving

      consult your doctor

      It is unknown if TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR affects your ability to drive. Drive or operate machinery only if you are alert.

    • Safety Warning

      Liver

      consult your doctor

      Please consult the doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      consult your doctor

      Please consult the doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      caution

      Please consult the doctor if you have any concerns regarding the usage of TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Practise safe sex by using latex or polyurethane condom; it helps in reducing contact with semen and vaginal fluids.
    • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
    • Do not share or re-use needles, other injection or drug equipment.
    • Eat a healthy and balanced diet. Include fruits and vegetables, and opt for lean protein and whole grains.
    • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
    • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.

    Patients Concern

    Disease/Condition Glossary

    HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help fight infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating it with antiretroviral drugs. 

    FAQs

    How does TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR work?

    TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR works by decreasing the amount of HIV in the blood. Thereby, it helps treat HIV infection.

    Does TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR affect birth control pills?

    Atazanavir and Ritonavir might make birth control hormonal pills less effective. Talk to the doctor regarding other forms of contraception such as condoms, diaphragm, cervical cap, or contraceptive sponge.

    Can I stop taking TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR on my own?

    Do not stop taking TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR without consulting your doctor, as it may reduce the effectiveness of anti-HIV therapy. Continue taking TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR for as long as your doctor has prescribed it to you to treat your condition effectually. Do not hesitate to speak with your doctor if you experience difficulty taking TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR.

    Available Medicines for

    TENOFOVIR DISOPROXIL FUMARATE+EMTRICITABINE+ATAZANAVIR+RITONAVIR