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About THIOPENTAL SODIUM

THIOPENTAL SODIUM belongs to the group of medicines called thiobarbiturates indicated for initiation of general anaesthesia, to provide hypnosis, as a part of treatment for cramps, and to reduce pressure in the skull in patients where the pressure is increased (if respiratory assistance is provided). It is also used to control seizures.

THIOPENTAL SODIUM contains Thiopental sodium, which works by slowing the activity of the brain or nervous system. It creates a sleep-like state and loss of consciousness to prevent pain and discomfort during surgery.

In some cases, THIOPENTAL SODIUM may cause side effects like irregular heartbeat, low blood pressure, sleepiness, coughing, and shivering. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Consult the doctor if you are pregnant or think you may be pregnant. Avoid breastfeeding during treatment with THIOPENTAL SODIUM. Do not drive or operate machinery for 24 to 36 hours after receiving THIOPENTAL SODIUM. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of THIOPENTAL SODIUM

General anaesthesia

Hypnosis 

Muscle cramps

Increased intracranial pressure

Seizures

Medicinal Benefits

THIOPENTAL SODIUM belongs to the group of medicines called thiobarbiturates indicated for initiation of general anaesthesia (a state of heavy sleep), to provide hypnosis (partial sleepiness), as a part of treatment for cramps, and to reduce pressure in the skull in patients where the pressure is increased (if respiratory assistance is provided). It is also used to control seizures. THIOPENTAL SODIUM contains Thiopental sodium, which works by slowing the activity of the brain or nervous system. It creates a sleep-like state and loss of consciousness to prevent pain and discomfort during surgery.

Directions for Use

THIOPENTAL SODIUM will be administered by a healthcare professional trained in anaesthesiology; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of THIOPENTAL SODIUM

  • Irregular heartbeat
  • Low blood pressure
  • Sleepiness
  • Coughing
  • Snoring
  • Shivering

In-Depth Precautions and Warning

Drug Warnings

Do not use THIOPENTAL SODIUM if you are allergic to any of its components or if you have respiratory obstruction (obstruction of the airways), asthma, myotonic dystrophy (hereditary muscle degeneration), porphyria, or severe shock. Inform the doctor if you have increased pressure in the skull, asthma or severe respiratory disorders, inflammation in the mouth, throat or jaw, heart or blood vessel disease, high blood pressure, inflammation of heart sac, hypovolemia (low blood volume), dehydration, severe bleeding or burns, myasthenia gravis, reduced function of the adrenocortical gland, severe anaemia, shock, liver or kidney impairment, metabolic disorder, addicted to alcohol or drugs of abuse. Consult the doctor if you are pregnant or think you may be pregnant. Avoid breastfeeding for at least 12 hours after the use of THIOPENTAL SODIUM. Let your doctor know if you are taking any prescription/non-prescription medicines or herbal supplements.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking painkillers (morphine, acetaminophen, tramadol).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have respiratory obstruction (obstruction of the airways), asthma, myotonic dystrophy (hereditary muscle degeneration), porphyria, or severe shock.

Drug-Drug Interactions Checker List:

  • MORPHINE
  • ACETAMINOPHEN
  • TRAMADOL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      The dose of THIOPENTAL SODIUM may need to be adjusted if you are addicted to alcohol or regularly consume large amounts of alcohol. Inform the doctor if you consume alcohol.

    • Safety Warning

      Pregnancy

      caution

      Thiopental sodium belongs to pregnancy category C. It should be used during pregnancy only if clearly needed.

    • Safety Warning

      Breast Feeding

      unsafe

      Thiopental sodium passes into breast milk. Avoid breastfeeding for at least 12 hours after receiving THIOPENTAL SODIUM.

    • Safety Warning

      Driving

      unsafe

      THIOPENTAL SODIUM has a major influence on your ability to drive and use machines. Therefore, avoid driving and operating machinery for 24 to 36 hours after receiving THIOPENTAL SODIUM.

    • Safety Warning

      Liver

      caution

      If you have a history of liver impairment, inform the doctor before receiving THIOPENTAL SODIUM. Your doctor may adjust the dose depending on your condition.

    • Safety Warning

      Kidney

      caution

      If you have a history of kidney impairment, inform the doctor before receiving THIOPENTAL SODIUM. Your doctor may adjust the dose depending on your condition.

    • Safety Warning

      Children

      caution

      Please consult the doctor if you have any concerns regarding the usage of THIOPENTAL SODIUM in children. The doctor may adjust the dose depending on the condition.

    Habit Forming

    Yes

    Diet & Lifestyle Advise

    SEIZURES:

    • Exercising regularly helps in maintaining weight and improving overall health. 

    • Rest well, and get plenty of sleep.

    • Avoid smoking and alcohol consumption.

    • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.

    • Have a seizure response plan; this helps those around you know what to do.

    • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.

    • Understand what triggers seizures and try reducing or avoiding them.

    • Please pay attention to overall health, as it can help in reducing seizure activity.

    • Install an alarm or emergency device to get assistance during a seizure attack.

    Patients Concern

    Disease/Condition Glossary

    Anaesthesia: Anaesthesia is the use of medications called anaesthetics to prevent pain during surgery or other procedures. This causes a loss of sensation, feeling, and awareness.

    Hypnosis: It is a condition in which a person is sleepy but not completely asleep.

    Increased intracranial pressure: Increased intracranial pressure is the rise in the pressure inside the skull, which may result in brain injury. It could be due to a rise in the pressure of the cerebrospinal fluid or a rise in pressure within the brain itself.

    Seizures: Seizures, also known as fits or convulsions, are a single occurrence of abnormal electrical activity in the brain. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

    FAQs

    How does THIOPENTAL SODIUM work?

    THIOPENTAL SODIUM works by slowing the activity of the brain or nervous system. Thereby, it prevents pain and discomfort during surgery.

    Is THIOPENTAL SODIUM safe for patients with low blood pressure?

    THIOPENTAL SODIUM may cause low blood pressure. Therefore, if you have hypotension/low blood pressure, inform the doctor.

    Does THIOPENTAL SODIUM cause breathing difficulties?

    THIOPENTAL SODIUM may cause breathing difficulty. However, consult the doctor immediately if you experience difficulty breathing, rash, wheezing, hives, itching, and dizziness, as these may be signs of a severe allergic reaction.

    Available Medicines for

    THIOPENTAL SODIUM