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About TOLPERISONE+PARACETAMOL

TOLPERISONE+PARACETAMOL belongs to the class of medicine called 'muscle relaxant' in combination with a painkiller, used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.

TOLPERISONE+PARACETAMOL is a combination of two drugs: Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of TOLPERISONE+PARACETAMOL include nausea, vomiting, dry mouth, dizziness, weakness and sleepiness. These side effects are not familiar to everyone and vary individually.

Let your doctor know if you use any prescription and non-prescription medications before starting TOLPERISONE+PARACETAMOL. Inform your doctor if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles) and phenylketonuria (a genetic disorder that causes an amino acid build-up, phenylalanine) and alcohol dependency. Consult your doctor before taking TOLPERISONE+PARACETAMOL if you are pregnant or planning for pregnancy. TOLPERISONE+PARACETAMOL may cause dizziness, so drive only if you are alert and focused. TOLPERISONE+PARACETAMOL should not be given to children as safety has not been established. Avoid consuming alcohol and TOLPERISONE+PARACETAMOL as it could lead to increased dizziness and risk of liver damage.

Uses of TOLPERISONE+PARACETAMOL

Muscle spasms.

Medicinal Benefits

TOLPERISONE+PARACETAMOL treats muscle spasms and consists of Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevents the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Directions for Use

Swallow TOLPERISONE+PARACETAMOL as a whole with a glass of water, do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TOLPERISONE+PARACETAMOL

  • Nausea
  • Vomiting
  • Dry mouth
  • Dizziness
  • Weakness
  • Sleepiness

In-Depth Precautions and Warning

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency before starting TOLPERISONE+PARACETAMOL. Consult your doctor before taking TOLPERISONE+PARACETAMOL if you are pregnant, planning for pregnancy or breastfeeding. TOLPERISONE+PARACETAMOL may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with TOLPERISONE+PARACETAMOL as it could lead to increased dizziness and risk of liver damage. TOLPERISONE+PARACETAMOL is not recommended in children as safety and efficacy is not established.

Drug Interactions

Drug-Drug Interactions: TOLPERISONE+PARACETAMOL may interact with anticoagulants (warfarin), drugs treating vomiting (metoclopramide, domperidone), cholesterol-lowering medications (cholestyramine) and anti-cancer medications (imatinib).

Drug-Food Interactions: Alcohol consumption may cause dizziness and increases the risk of liver damage.

Drug-Disease Interactions: Before using TOLPERISONE+PARACETAMOL, let your doctor know if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • IMATINIB
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended to avoid alcohol consumption while taking TOLPERISONE+PARACETAMOL. Alcohol intake, along with TOLPERISONE+PARACETAMOL, may cause increased dizziness and risk of liver damage.

    • Safety Warning

      Pregnancy

      caution

      TOLPERISONE+PARACETAMOL should be used with caution during pregnancy. Please consult your doctor before taking TOLPERISONE+PARACETAMOL.

    • Safety Warning

      Breast Feeding

      caution

      TOLPERISONE+PARACETAMOL should be used with caution during breastfeeding. Please consult your doctor before taking TOLPERISONE+PARACETAMOL.

    • Safety Warning

      Driving

      caution

      TOLPERISONE+PARACETAMOL may make you feel dizzy. Do not drive or operate machinery if you experience dizziness.

    • Safety Warning

      Liver

      caution

      Please consult your doctor since TOLPERISONE+PARACETAMOL should be used with caution in patients with liver impairment/liver disease.

    • Safety Warning

      Kidney

      caution

      Please consult your doctor since TOLPERISONE+PARACETAMOL should be used with caution in patients with kidney impairment/kidney disease.

    • Safety Warning

      Children

      unsafe

      TOLPERISONE+PARACETAMOL is not recommended in children as safety and efficacy is not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
    • Massages can also be helpful.
    • Avoid freezing and hot temperatures.
    • Avoid wearing tight-fitting clothes, instead, wear loose garments.
    • Rest well and get plenty of sleep.
    • To avoid developing pressure sores, change your position at least every two hours.
    • Hot or cold therapy can haelp treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
    • Stay hydrated, drink plenty of water.

    Special Advise

    • Let your doctor know that you are taking TOLPERISONE+PARACETAMOL if you are undergoing any medical tests.
    • TOLPERISONE+PARACETAMOL may cause fluid retention (oedema), hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history.
    • Explain a detail history to the doctor as use of TOLPERISONE+PARACETAMOL is contraindicated in patients with myasthenia gravis.

    Patients Concern

    Disease/Condition Glossary

    Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

    Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.

    FAQs

    How does TOLPERISONE+PARACETAMOL work?

    TOLPERISONE+PARACETAMOL is a combination of two drugs: Tolperisone and Paracetamol. Tolperisone works on the spinal cord and brain to relieve contraction or muscle stiffness. Paracetamol works by blocking the action of certain chemical messengers that cause pain.

    Can I stop taking TOLPERISONE+PARACETAMOL if my symptoms are relieved?

    TOLPERISONE+PARACETAMOL is usually used for a short period and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.

    Are there any specific contraindications while using TOLPERISONE+PARACETAMOL?

    TOLPERISONE+PARACETAMOL is to be carefully administered in patients with alcohol dependency, kidney or liver damage, myasthenia gravis (fatigue of muscles) and phenylketonuria (a genetic disorder that causes the build-up of an amino acid, phenylalanine). Please consult your doctor before starting TOLPERISONE+PARACETAMOL if you have a medical history.

    Will I become TOLPERISONE+PARACETAMOL addicted?

    No, there are no instances of any patient being TOLPERISONE+PARACETAMOL-addicted.

    Should I take TOLPERISONE+PARACETAMOL with or without food?

    TOLPERISONE+PARACETAMOL may cause stomach upset; hence taking it with food will prevent you from getting an upset stomach.

    Available Medicines for

    TOLPERISONE+PARACETAMOL