TRETINOIN+CLINDAMYCIN belongs to the class of dermatological preparations called 'antiacne' used to treat acne (pimples). Acne is a common skin condition and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feeds on sebum (natural oil produced by skin) causing redness and swelling.
TRETINOIN+CLINDAMYCIN is a combination of two medicines, namely: Tretinoin (vitamin A) and Clindamycin (antibiotic). Tretinoin is a form of vitamin A that reduces oil production in the skin, replenishes the skin, and helps keep your pores open. Clindamycin belongs to the class of antibiotics that inhibits the production of essential proteins that are necessary for bacteria to grow, multiply, and increase in numbers. Altogether it stops or slows down the growth of bacteria and prevents the growth of acne.
Take TRETINOIN+CLINDAMYCIN as prescribed by your doctor. You are advised to take TRETINOIN+CLINDAMYCIN for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience application site reactions (burning, irritation, itching, and redness), dermatitis, skin peeling, and dryness. Most of these side effects of TRETINOIN+CLINDAMYCIN do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
If you are known to be allergic to TRETINOIN+CLINDAMYCIN or any other medicines, please tell your doctor. If you have a chronic inflammatory bowel disease (e.g. Crohn’s disease or ulcerative colitis). If you are suffering from other acute inflammatory conditions of the skin (e.g. folliculitis), especially around the mouth (perioral dermatitis). If you have a history of colitis with past antibiotic use which is characterized by prolonged or significant diarrhoea or abdominal cramps. Do not apply TRETINOIN+CLINDAMYCIN to cuts, open wounds, broken, sunburnt, or sensitive skin areas. Avoid sun exposure while using TRETINOIN+CLINDAMYCIN as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you have intestine problems or eczema, please inform your doctor before taking TRETINOIN+CLINDAMYCIN. If you are pregnant or breastfeeding, please inform your doctor before taking TRETINOIN+CLINDAMYCIN.
Acne (pimple)
TRETINOIN+CLINDAMYCIN is a combination of two medicines, namely: Tretinoin (vitamin A) and Clindamycin (antibiotic) primarily used to treat acne (pimples). Tretinoin is a form of vitamin A that reduces oil production in the skin, replenishes the skin, and helps keep your pores open. Clindamycin belongs to the class of antibiotics that inhibits the production of essential proteins that are necessary for bacteria to grow, multiply, and increase in numbers. Altogether it stops or slows down the growth of bacteria and prevents the growth of acne.
If you are known to be allergic to TRETINOIN+CLINDAMYCIN or any other medicines, please tell your doctor. If you have a chronic inflammatory bowel disease (e.g. Crohn’s disease or ulcerative colitis). If you are suffering from other acute inflammatory conditions of the skin (e.g. folliculitis), especially around the mouth (perioral dermatitis). Avoid sun exposure while using TRETINOIN+CLINDAMYCIN as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you have a history of colitis (chronic digestive disease) with past antibiotic use which is characterized by prolonged or significant diarrhoea or abdominal cramps. Do not apply TRETINOIN+CLINDAMYCIN to cuts, open wounds, broken, sunburnt, or sensitive skin areas. Avoid sun exposure while using TRETINOIN+CLINDAMYCIN as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you have intestine problems or eczema, please inform your doctor before taking TRETINOIN+CLINDAMYCIN. If you are pregnant or breastfeeding, please inform your doctor before taking TRETINOIN+CLINDAMYCIN.
Drug-Drug Interactions: TRETINOIN+CLINDAMYCIN may interact with antibiotics (erythromycin, metronidazole), blood thinner (warfarin), keratolytic agents (benzoyl peroxide, salicylic acid), and skeletal muscle relaxants (atracurium, cisatracurium).
Drug-Food Interactions: If you are taking grapefruit juice or alcohol, please inform your doctor before taking TRETINOIN+CLINDAMYCIN.
Drug-Disease Interactions: If you have intestine problems or eczema, please inform your doctor before taking TRETINOIN+CLINDAMYCIN.
The interaction of TRETINOIN+CLINDAMYCIN with alcohol is unknown. Please consult a doctor before consuming alcohol while using TRETINOIN+CLINDAMYCIN.
Do not use TRETINOIN+CLINDAMYCIN if you are pregnant or thinking of becoming pregnant. Your doctor can give you more information.
The safety of TRETINOIN+CLINDAMYCIN in breastfeeding mothers is unknown. Therefore, you should not use it if you are breastfeeding.
TRETINOIN+CLINDAMYCIN usually does not affect your ability to drive or operate machinery.
If you have any concerns regarding the use of TRETINOIN+CLINDAMYCIN in patients with Liver problems, please consult a doctor.
If you have any concerns regarding the use of TRETINOIN+CLINDAMYCIN in patients with kidney problems, please consult a doctor.
TRETINOIN+CLINDAMYCIN is not recommended for children below 12 years as the safety and effectiveness were not established.
Acne (pimple): It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages but is most common among teenagers. Acne symptoms include pus-filled pimples, uninflamed (not swollen) blackheads, red, large, and tender bumps. The treatment for acne includes certain creams, cleansers, and antibiotics.