Tedizolid
About Tedizolid
Tedizolid is used to treat bacterial infections of the skin and skin structures. It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections and linezolid-resistant infections, including methicillin-resistant Staphylococcus aureus. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body.
Tedizolid contains Tedizolid, which works by inhibiting the bacteria's ability to produce proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.
In some cases, you may experience common side effects, such as thrush (a fungal infection), headache, a metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take Tedizolid on your own, as self-medication may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections. Consult your doctor if you are pregnant or planning to become pregnant before taking Tedizolid. Tedizolid passes into breastmilk, so do not take Tedizolid if you are breastfeeding.
Medicinal Benefits
- Tedizolid is an antibiotic primarily used to treat skin infections.
- It is also effective in treating vancomycin-resistant enterococcal infections.
- Tedizolid does not work against infections caused by the virus, including cold and flu.
Directions for Use
- Tedizolid can be taken with or without food, as advised by your doctor.
- Your doctor will decide the appropriate dosage and timing based on your medical condition.
- Swallow Tedizolid as a whole with a glass of water.
- Do not crush or chew this medication.
Side Effects of Tedizolid
- Headache
- Metallic taste
- Diarrhoea
- Nausea
- Vomiting
- Dizziness
- Constipation
- Indigestion
Drug Warnings
- Do not take Tedizolid if you are allergic to any of its contents.
- Also avoid taking Tedizolid if you are taking or have taken monoamine oxidase (MAO) inhibitors in the last 14 days.
- Talk to your doctor if you have high blood pressure, an overactive thyroid, phaeochromocytoma (tumour of adrenal glands), carcinoid syndrome (tumours of the hormone system), manic depression, schizophrenia, confusion, or other mental problems.
- Inform your doctor if you bruise or bleed easily, have anaemia (low red blood cells), are prone to infections, have a history of seizures, are on dialysis, have diarrhoea, or kidney or liver problems.
- Consult your doctor immediately if you experience a throbbing headache after eating or drinking, vision problems, loss of sensation or tingling and prickling sensations in your arms and legs, persistent diarrhoea, nausea, vomiting, abdominal pain, or rapid breathing.
- Consult your doctor if you are pregnant before taking Tedizolid.
- Tedizolid passes into breastmilk, so do not take Tedizolid if you are breastfeeding.
- Tedizolid may cause dizziness and vision problems; therefore, exercise caution when driving and operating machinery.
- Avoid alcohol consumption while taking Tedizolid, as it may cause increased dizziness.
Drug Interactions
Drug-Drug Interactions: Tedizolid may interact with certain medications, such as antiasthma drugs (salbutamol, terbutaline), antidepressants (citalopram, amitriptyline, fluoxetine, imipramine), antimigraine medications (sumatriptan), decongestants (pseudoephedrine), antiallergics (epinephrine), drugs used to increase blood pressure (dopamine), opioid pain relievers (pethidine), antianxiety drugs (buspirone), antibiotics (rifampicin), and blood thinners (warfarin).
Drug-Food Interactions: Avoid foods and drinks containing tyramine, such as cheese, yeast extracts, soybean extracts, alcohol, beer, or wine while taking Tedizolid, as it may interact with tyramine and lead to an increase in blood pressure.
Drug-Disease Interactions: Inform your doctor before taking Tedizolid if you have colitis (inflammation in the lining of the colon), seizures, high blood pressure, acidosis (increased acidity in the blood), carcinoid syndrome (cancerous tumour which secretes chemicals into the bloodstream), hemodialysis, hypoglycaemia (low blood sugar levels), neuropathy, or kidney or liver disease.
Drug-Drug Interactions Checker List:
Safety Advice

Alcohol
unsafeAvoid consuming alcohol while taking Tedizolid, as it may cause increased dizziness.

Pregnancy
consult your doctorIf you are pregnant, please consult your doctor before using Tedizolid. Your doctor will prescribe it only if the potential benefits justify the possible risks.

Breast Feeding
consult your doctorIf you are a breastfeeding mother, please consult your doctor before using Tedizolid. Your doctor will prescribe it only if the potential benefits justify the possible risks.

Driving
cautionTedizolid may cause dizziness and vision problems. So, drive only if you are alert.

Liver
consult your doctorIf you have any liver problems, please consult your doctor to discuss any concerns regarding the use of Tedizolid.

Kidney
consult your doctorIf you have any kidney problems, please consult your doctor to discuss any concerns regarding the use of Tedizolid.

Children
unsafeTedizolid is not recommended for children below 18 years of age.
Habit Forming
Diet & Lifestyle Advise
- Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, take foods rich in probiotics, such as yogurt/curd, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
- Eat fibre-rich food like whole grains, lentils, berries, broccoli, peas, and bananas.
- Avoid foods rich in calcium, grapefruit, and grapefruit juice, as they might hinder the absorption of antibiotics.
- Avoid consuming tyramine-rich food or drinks, such as meat, cheese, fish, red wine, beer, certain beans, and fermented yeast products.
- Avoid consumption of alcohol and usage of tobacco.
Patients Concern
Disease/Condition Glossary
Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Infectious or harmful bacteria can make you sick and reproduce quickly in the body. These destructive bacteria produce toxins that can damage tissue and make you ill. Symptoms include fever, chills, and fatigue. Anyone can become infected with bacteria. However, people with a weakened immune system or those taking immunosuppressive medications are more prone to bacterial infections.
FAQs
Tedizolid is an antibiotic used to treat bacterial skin infections. It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections.
Tedizolid contains Tedizolid (an antibiotic) that works by preventing bacteria from making proteins necessary for their growth and multiplication, ultimately killing them. Thus, it helps treat the bacterial infection.
It is recommended to complete the course of Tedizolid even if you feel better, as it is an antibiotic, and leaving it in between may lead to even more severe infection. To treat your condition effectively, continue taking Tedizolid for as long as your doctor has prescribed it.
Diarrhoea might be a side effect of Tedizolid. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have prolonged diarrhoea with abdominal pain, stop taking Tedizolid and consult your doctor. Do not take anti-diarrheal medicine on your own.
You should avoid eating large amounts of foods that contain high levels of tyramine. Foods that are fermented, cured, aged or spoiled contain a high amount of tyramine, e.g. cheese, red wine, pickles, overripe fruits, etc. Consuming tyramine while taking Linezolid can result in an elevation of blood pressure, which may result in an emergency.
You should take it twice a day, every 12 hours, for example, at 8 a.m. and 8 p.m. You can take it before, with, or after food. Your doctor or clinician will determine the duration of the treatment course.
Common side effects of Tedizolid may include headache, metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

