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COBIX 100MG CAPSULE

COBIX 100MG CAPSULE is used to reduce pain and swelling in muscles and joints. It treats painful conditions of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck), and menstrual pain. It contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme that causes pain and inflammation in the body. Thereby, it helps relieve pain and swelling. It may cause side effects such as indigestion, stomach pain, diarrhoea, oedema, and flatulence.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Cobix 100mg Capsule
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

Drug-Drug Interactions

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CelecoxibEliglustat
Critical
CelecoxibKetorolac
Critical

Drug-Drug Interactions

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CelecoxibEliglustat
Critical
How does the drug interact with Cobix 100mg Capsule:
Taking eliglustat with Cobix 100mg Capsule can significantly increase the blood levels of eliglustat. This may increase the risk of serious side effects.

How to manage the interaction:
Taking Cobix 100mg Capsule with Eliglustat is not recommended, but can be taken together if prescribed by a doctor. However, consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate and weak pulse. Do not discontinue any medications without consulting a doctor.
CelecoxibKetorolac
Critical
How does the drug interact with Cobix 100mg Capsule:
Taking Ketorolac with Cobix 100mg Capsule can increase the risk of side effects such as gastrointestinal bleeding and ulcers.

How to manage the interaction:
Taking Cobix 100mg Capsule with Ketorolac is not recommended, but can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
CelecoxibKetorolac tromethamine
Critical
How does the drug interact with Cobix 100mg Capsule:
Taking Ketorolac with Cobix 100mg Capsule can increase the risk of gastrointestinal bleeding and ulcers,

How to manage the interaction:
Taking Ketorolac tromethamine with Cobix 100mg Capsule is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
CelecoxibCidofovir
Critical
How does the drug interact with Cobix 100mg Capsule:
Co-administration of Cidofovir with Cobix 100mg Capsule can increase the risk of kidney problems.

How to manage the interaction:
Taking Cobix 100mg Capsule with Cidofovir is not recommended, please consult your doctor before taking it. However, consult the doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to a doctor.
CelecoxibMeloxicam
Critical
How does the drug interact with Cobix 100mg Capsule:
Co-administration of Cobix 100mg Capsule with Meloxicam can increase the risk or severity of bleeding and ulcers of the stomach lining leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Cobix 100mg Capsule is not recommended, but can be taken together if prescribed by a doctor. However, consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a dcovct
CelecoxibThioridazine
Critical
How does the drug interact with Cobix 100mg Capsule:
Taking thioridazine and Cobix 100mg Capsule may increases the blood levels of thioridazine which may cause irregular heart rhythm.

How to manage the interaction:
Taking Cobix 100mg Capsule with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without first talking to your doctor.
CelecoxibTeriflunomide
Severe
How does the drug interact with Cobix 100mg Capsule:
Taking Teriflunomide with Cobix 100mg Capsule affects the liver and may increase the risk of liver problems.

How to manage the interaction:
Although taking Cobix 100mg Capsule and Teriflunomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
CelecoxibPiroxicam
Severe
How does the drug interact with Cobix 100mg Capsule:
Coadministration of Cobix 100mg Capsule with piroxicam can increase the risk and severity of gastrointestinal toxicity.

How to manage the interaction:
Although there is a interaction between Piroxicam and Cobix 100mg Capsule, but it can be taken if your doctor has advised it. However, consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
CelecoxibLeflunomide
Severe
How does the drug interact with Cobix 100mg Capsule:
Taking leflunomide with Cobix 100mg Capsule affects the liver and may increase the risk of liver problems.

How to manage the interaction:
Although taking Cobix 100mg Capsule and leflunomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
CelecoxibMefenamic acid
Severe
How does the drug interact with Cobix 100mg Capsule:
Coadministration of Mefenamic acid with Cobix 100mg Capsule can increase the risk or severity of bleeding and ulcers of the stomach.

How to manage the interaction:
Taking Mefenamic acid with Cobix 100mg Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, loos stools, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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