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Ovral L Tablet is used for contraception and treating dysmenorrhea (irregular and painful periods). It contains Ethinylestradiol and Levonorgestrel, which maintains a normal menstrual cycle (periods) in women. It works by fulfilling the deficiency of estrogen hormone, thereby preventing symptoms like night sweats, hot flashes, and mood swings. Also, it prevents the release of an egg from the ovary (female reproductive cells) or prevents fertilization of an egg by sperm (male reproductive cells). It may also change the lining of the uterus to prevent the development of a pregnancy. It may cause side effects such as stomach pain, headache, nausea, breast pain, weight gain, and irregular uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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LevonorgestrelEtretinate
Critical

Drug-Drug Interactions

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LevonorgestrelEtretinate
Critical
How does the drug interact with Ovral L Tablet:
Using etretinate and Ovral L Tablet can cause severe birth defects.

How to manage the interaction:
Taking Etretinate with Ovral L Tablet can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ovral L Tablet:
Coadministration of Acitretin with Ovral L Tablet can increase the risk and severity of birth defects in unborn when taken by a pregnant woman.

How to manage the interaction:
Taking Acitretin with Ovral L Tablet together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Never use acitretin if you are pregnant. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ovral L Tablet:
Taking Ovral L Tablet with Tranexamic acid may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.

How to manage the interaction:
Taking Tranexamic acid with Ovral L Tablet may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ovral L Tablet:
Taking Ovral L Tablet with Tranexamic acid may increase the risk of blood clot formation.

How to manage the interaction:
Taking Ovral L Tablet with Tranexamic acid is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ovral L Tablet:
Topiramate may lower the blood levels and effects of Ovral L Tablet, making it less effective as a type of birth control.

How to manage the interaction:
Although taking Ovral L Tablet and topiramate can lead to an interaction, it can be taken if prescribed by a doctor. If you have been receiving hormone replacement therapy (Ovral L Tablet) for menopause, you should contact the doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not stop using any medications without talking to a doctor.
LevonorgestrelFosamprenavir
Severe
How does the drug interact with Ovral L Tablet:
Using Ovral L Tablet together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Although there is a possible interaction between Ovral L Tablet and Fosamprenavir, you can take these medicines together if prescribed by a doctor. If you notice any of these signs, make sure to contact a doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without talking to a doctor.
LevonorgestrelSugammadex
Severe
How does the drug interact with Ovral L Tablet:
Taking Ovral L Tablet and Sugammadex may reduce the blood levels and effects of Ovral L Tablet.

How to manage the interaction:
Although there is a possible interaction between Sugammadex and Ovral L Tablet, you can take these medicines together if prescribed by a doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ovral L Tablet:
Using Ovral L Tablet with griseofulvin may reduce Ovral L Tablet blood levels and effects.

How to manage the interaction:
Although taking Ovral L Tablet and griseofulvin together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment(Ovral L Tablet) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ovral L Tablet:
Taking Ovral L Tablet with eslicarbazepine may reduce the blood levels and effects of Ovral L Tablet. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Although taking Ovral L Tablet and eslicarbazepine results in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Ovral L Tablet:
Taking Ovral L Tablet and Phenobarbital may lower Ovral L Tablet blood levels and effects.

How to manage the interaction:
Although taking phenobarbital and Ovral L Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment (Ovral L Tablet) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ETHINYLESTRADIOL-0.03MG+LEVONORGESTREL-0.15MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ETHINYLESTRADIOL-0.03MG+LEVONORGESTREL-0.15MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Taking Grapefruit or Grapefruit juice while on the treatment with Ethinylestradiol, Levonorgestrel can lead to increase in blood levels of Ethinylestradiol, Levonorgestrel. Avoid or limit the consumption of grapefruit and grapefruit juice during treatment with Ethinylestradiol, Levonorgestrel.

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