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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lexanox Plus Oral Paste is used to treat canker sores, also called aphthous ulcers in the mouth. Mouth ulcers are small, painful lesions that develop in the mouth or at the base of the gums. It contains Amlexanox and Lidocaine, which work by blocking the chemical messengers that cause pain, redness and inflammation due to mouth ulcers. It forms a protective film over the ulcer and fastens healing. This medicine may sometimes cause side effects such as reaction to the application site, such as a slight burning or stinging sensation.

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Side effects of Lexanox Plus Oral Paste, 5 gm
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.

Drug-Drug Interactions

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LidocaineArbutamine
Critical
LidocaineSaquinavir
Critical

Drug-Drug Interactions

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LidocaineArbutamine
Critical
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Lexanox Plus Oral Paste, 5 gm with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineSaquinavir
Critical
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with Saquinavir can increase the blood levels of Lexanox Plus Oral Paste, 5 gm and cause an irregular heart rhythm.

How to manage the interaction:
Taking Lexanox Plus Oral Paste, 5 gm with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Combination of chloroquine and Lexanox Plus Oral Paste, 5 gm can increase the risk of methemoglobinemia (an uncommon disease that can result in low oxygen levels in tissues and important organs).

How to manage the interaction:
Taking chloroquine and Lexanox Plus Oral Paste, 5 gm together can possibly result in an interaction, it can be taken if your doctor has advised it. If you experience any of the following symptoms: gray discoloration of the skin, abnormal blood coloring, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, rapid heartbeat, palpitations, anxiety, or confusion, consult your doctor
LidocaineIomeprol
Severe
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm and Iomeprol may increase the risk of causing seizures(fits).

How to manage the interaction:
There may be a possibility of interaction between Lexanox Plus Oral Paste, 5 gm and Iomeprol, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Combining Sulfasalazine with Lexanox Plus Oral Paste, 5 gm can increase the risk of methemoglobinemia (a rare red blood cell disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Co-administration of Sulfasalazine with Lexanox Plus Oral Paste, 5 gm can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with bupropion can increase the risk of seizures(fits).

How to manage the interaction:
Co-administration of bupropion along with Lexanox Plus Oral Paste, 5 gm can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Coadministration of Ifosfamide with Lexanox Plus Oral Paste, 5 gm can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Ifosfamide and Lexanox Plus Oral Paste, 5 gm, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with Nitrofurantoin may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Nitrofurantoin with Lexanox Plus Oral Paste, 5 gm together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with Trimethoprim may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Trimethoprim with Lexanox Plus Oral Paste, 5 gm can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience, gray skin color, feeling sick, having a headache, feeling dizzy or lightheaded, feeling tired, having trouble breathing, a fast or irregular heartbeat, feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking tramadol with Lexanox Plus Oral Paste, 5 gm can increase the risk of seizures(fits).

How to manage the interaction:
Taking Lexanox Plus Oral Paste, 5 gm with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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