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Adipin Plus 5mg/50mg Tablet

Adipin Plus 5mg/50mg Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Atenolol, which relax and widen the constricted blood vessels. This ultimately reduces the heart's workload and makes the heart more efficient in pumping blood throughout the body. Also, it blocks stress hormones like adrenaline and epinephrine, thereby slowing down the increased heart rate. Thus, it helps lower high blood pressure, reduces the chances of a heart attack or stroke in the future. It may cause common side effects such as nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth in the ears, face, neck, and trunk), slow heart rate, oedema (swelling), constipation, and tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Adipin Plus 5mg/50mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Reducing the amount of time you spend outside and indoors in the cold.
  • keeping your hands warm by donning mittens, gloves, or other protective clothing.
  • Observing a skincare regimen that safeguards your fingers and hands.
  • To improve circulation, give your hands and feet a little massage.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineRifampicin
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Adipin Plus 5mg/50mg Tablet:
Using Adipin Plus 5mg/50mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Adipin Plus 5mg/50mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineRifampicin
Severe
How does the drug interact with Adipin Plus 5mg/50mg Tablet:
Coadministration of Adipin Plus 5mg/50mg Tablet and rifampicin together may lower Adipin Plus 5mg/50mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Adipin Plus 5mg/50mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Adipin Plus 5mg/50mg Tablet:
Coadministration of Adipin Plus 5mg/50mg Tablet with itraconazole may significantly raise the blood levels and effects of Adipin Plus 5mg/50mg Tablet.

How to manage the interaction:
Adipin Plus 5mg/50mg Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineRifabutin
Severe
How does the drug interact with Adipin Plus 5mg/50mg Tablet:
Using Adipin Plus 5mg/50mg Tablet and rifabutin together may lower Adipin Plus 5mg/50mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Adipin Plus 5mg/50mg Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
AmlodipinePhenytoin
Severe
How does the drug interact with Adipin Plus 5mg/50mg Tablet:
Using Adipin Plus 5mg/50mg Tablet and phenytoin together may drastically lower Adipin Plus 5mg/50mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Adipin Plus 5mg/50mg Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Adipin Plus 5mg/50mg Tablet:
Using Adipin Plus 5mg/50mg Tablet and primidone together may lower Adipin Plus 5mg/50mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Adipin Plus 5mg/50mg Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePhenobarbital
Severe
How does the drug interact with Adipin Plus 5mg/50mg Tablet:
Using phenobarbital and Adipin Plus 5mg/50mg Tablet may drastically lower Adipin Plus 5mg/50mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Adipin Plus 5mg/50mg Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineCeritinib
Severe
How does the drug interact with Adipin Plus 5mg/50mg Tablet:
Coadministration of Ceritinib together with Adipin Plus 5mg/50mg Tablet can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Adipin Plus 5mg/50mg Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Adipin Plus 5mg/50mg Tablet:
Coadministration of Adipin Plus 5mg/50mg Tablet and Rifapentine may significantly reduce the blood levels of Adipin Plus 5mg/50mg Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Adipin Plus 5mg/50mg Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Adipin Plus 5mg/50mg Tablet:
Using a combination of Adipin Plus 5mg/50mg Tablet and enzalutamide may drastically lower Adipin Plus 5mg/50mg Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Adipin Plus 5mg/50mg Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+ATENOLOL-50MGFruit juices, Fruits
Mild

Drug-Food Interactions

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AMLODIPINE-5MG+ATENOLOL-50MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
The consumption of grapefruit juice may slightly increase plasma concentrations of amlodipine. Avoid consumption of grapefruit juice while being treated with Adipin Plus 5mg/50mg Tablet.

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