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Atortrue F 10mg/145mg Tablet is used in the treatment of high lipid levels (cholesterol and triglycerides levels) and prevention of heart diseases and blood vessel blockage. It contains Atorvastatin and Fenofibrate, which lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). In some cases, you may experience allergic reactions, hyperglycemia (excess of glucose in the bloodstream), headache, blurred vision, stomach pain, constipation, headaches, joint swelling (oedema), joint pain, muscle pain, back pain, slow heart rate, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Side effects of Atortrue F 10mg/145mg Tablet
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Abnormal liver function requires immediate medical attention. Your doctor may recommend lifestyle modifications along with needed medication.
  • Avoid intake of alcohol as it has a direct impact on liver functioning.
  • Prevent medications like paracetamol, over-the-counter painkillers or those mentioned by your doctor, as they may have issues getting metabolised in your body.
  • If you have overweight issues, losing weight can be a good thing to manage abnormal liver function.
  • Cut down the number of fatty foods that are taken daily.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Atortrue F 10mg/145mg Tablet:
Taking Atortrue F 10mg/145mg Tablet with Posaconazole can increase the blood levels of Atortrue F 10mg/145mg Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Atortrue F 10mg/145mg Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atortrue F 10mg/145mg Tablet:
Co- administration of Atortrue F 10mg/145mg Tablet with Leflunomide can cause liver issues and taking it with other medications that might harm the liver, such as Atortrue F 10mg/145mg Tablet, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Atortrue F 10mg/145mg Tablet, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibrateMipomersen
Severe
How does the drug interact with Atortrue F 10mg/145mg Tablet:
Mipomersen may cause liver problems and using it with Atortrue F 10mg/145mg Tablet may increase that risk.

How to manage the interaction:
There may be a possibility of interaction between Atortrue F 10mg/145mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.
How does the drug interact with Atortrue F 10mg/145mg Tablet:
Taking Atortrue F 10mg/145mg Tablet with Pitavastatin can increase the risk of muscle problems like liver damage and rhabdomyolysis (the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is a possible interaction between Pitavastatin and Atortrue F 10mg/145mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience unexpected bruising or bleeding, skin rash, itching, exhaustion, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without consulting a doctor.
FenofibrateCerivastatin
Severe
How does the drug interact with Atortrue F 10mg/145mg Tablet:
When Atortrue F 10mg/145mg Tablet is used with cerivastatin, the risk of adverse effects such as liver damage and rhabdomyolysis, an uncommon but serious illness involving the breakdown of skeletal muscle tissue, increases. Rhabdomyolysis can cause kidney damage.

How to manage the interaction:
Although taking Atortrue F 10mg/145mg Tablet and Cerivastatin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience unexplained muscular pain, soreness, or weakness while taking these drugs, inform a doctor immediately, especially if these symptoms are accompanied by fever or dark-colored urine. Furthermore, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibrateLomitapide
Severe
How does the drug interact with Atortrue F 10mg/145mg Tablet:
Co-administration of Lomitapide with Atortrue F 10mg/145mg Tablet may cause liver damage and using it with other drugs that might adversely impact the liver, such as Atortrue F 10mg/145mg Tablet, may enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Atortrue F 10mg/145mg Tablet and Lomitapide, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
FenofibratePravastatin
Severe
How does the drug interact with Atortrue F 10mg/145mg Tablet:
When Atortrue F 10mg/145mg Tablet is used with pravastatin, it increases the chance of adverse effects such as liver damage and rhabdomyolysis, an uncommon but deadly illness characterised by the destruction of skeletal muscle tissue. Rhabdomyolysis can cause kidney damage.

How to manage the interaction:
Co-administration of Atortrue F 10mg/145mg Tablet with Pravastatin can result in an interaction, but it can be taken if a doctor has advised it. Inform a doctor immediately, if you have unexplained muscular pain, soreness, or weakness while taking these medications, especially if these symptoms are accompanied by fever or dark-colored urine. Furthermore, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, or yellowing of the skin or eyes, consult the doctor immediately.
FenofibrateDicoumarol
Severe
How does the drug interact with Atortrue F 10mg/145mg Tablet:
co-administration of Atortrue F 10mg/145mg Tablet with dicoumarol can enhance the effects of dicumarol, causing you to bleed more readily.

How to manage the interaction:
Taking Atortrue F 10mg/145mg Tablet with Dicoumarol together can result in an interaction, but it can be taken if a doctor has advised it. If you notice unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these medications, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atortrue F 10mg/145mg Tablet:
Taking Warfarin together with Atortrue F 10mg/145mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Although taking Atortrue F 10mg/145mg Tablet and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness consult a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Atortrue F 10mg/145mg Tablet:
Coadministration of Atortrue F 10mg/145mg Tablet with Atorvastatin can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although taking Atortrue F 10mg/145mg Tablet and atorvastatin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ATORVASTATIN-10MG+FENOFIBRATE-145MGFruit juices
Moderate

Drug-Food Interactions

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ATORVASTATIN-10MG+FENOFIBRATE-145MGFruit juices
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Blood levels of atorvastatin can rise after consuming grapefruit juice. Before quitting the drug, speak to a doctor even though there may be an interaction. Additionally, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, or yellowing of the skin or eyes, you should consult a doctor. Without first consulting your doctor, never stop taking the medication.

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