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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dexamethasone Tablet 100's is used to treat inflammatory conditions such as allergic disorders and skin conditions. It is also used to treat ulcerative colitis, arthritis, lupus, psoriasis and breathing disorders. Furthermore, it is approved for the treatment of coronavirus disease 2019 (COVID-19) in adult and adolescent patients (aged 12 years and older with a body weight of at least 40 kg) who require supplemental oxygen therapy. It contains Dexamethasone, which works by blocking the release of substances that cause inflammation. Some people may experience side effects like weight gain, indigestion, headache, dizziness, rash, fluid retention (swelling in your hands or ankles), sleep problems, mild mood changes and nausea. Inform the doctor if you have an infection that affects the whole body or if you need to have a vaccination, particularly live virus vaccines.

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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dexamethasone Tablet Tablet:
When Dexamethasone Tablet is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine and Dexamethasone Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexamethasone Tablet Tablet:
When Regorafenib is taken with Dexamethasone Tablet, may significantly reduce the blood levels of Regorafenib.

How to manage the interaction:
Co-administration of Regorafenib and Dexamethasone Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexamethasone Tablet Tablet:
Co-administration of Desmopressin with Dexamethasone Tablet may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Dexamethasone Tablet and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DexamethasoneRilpivirine
Critical
How does the drug interact with Dexamethasone Tablet Tablet:
When Rilpivirine is taken with Dexamethasone Tablet, may significantly reduce the blood levels of Rilpivirine.

How to manage the interaction:
Co-administration of Rilpivirine and Dexamethasone Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexamethasone Tablet Tablet:
Taking Cladribine with Dexamethasone Tablet can increase the chances of serious infections.

How to manage the interaction:
Although there is a possible interaction between Cladribine and Dexamethasone Tablet, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexamethasone Tablet Tablet:
Dexamethasone Tablet and Ofloxacin co-administration can result in tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture.

How to manage the interaction:
Taking Ofloxacin with Dexamethasone Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DexamethasoneToremifene
Severe
How does the drug interact with Dexamethasone Tablet Tablet:
When Toremifene is taken with Dexamethasone Tablet, may reduce the effectiveness of Toremifene.

How to manage the interaction:
There may be a possibility of interaction between Dexamethasone Tablet and Toremifene, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dexamethasone Tablet Tablet:
Taking Dexamethasone Tablet with Bosutinib can decrease the blood levels of Bosutinib, reducing its effectiveness in treating your condition.

How to manage the interaction:
Although there is an interaction between Bosutinib and Dexamethasone Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dexamethasone Tablet Tablet:
Taking Dexamethasone Tablet with Leflunomide may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dexamethasone Tablet Tablet:
Taking Dexamethasone Tablet may lower the blood levels of Sunitinib in some patients, making the medication less effective.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone Tablet can be taken with Sunitinib if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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DEXAMETHASONE-0.5MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEXAMETHASONE-0.5MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking Dexamethasone Tablet with Caffeine may increase the side effects of Dexamethasone Tablet. Avoid consuming caffeine while taking Dexamethasone Tablet.

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