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compositionComposition:GLIMEPIRIDE-1MG
prescriptionPrescription Medicine

Glymepiz 1mg Tablet is used to lower raised blood sugar levels in Type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus - NIDDM). It contains Glimepiride which acts on insulin-secreting cells called beta cells inside the pancreas and activates calcium channels on cells which lets insulin pass out of the cell. This insulin then makes each cell in the body take up glucose and utilize it, thus lowering raised blood glucose. It may cause side effects such as allergic reaction (skin rash, hives, sensitivity to sun rays), liver dysfunction (jaundice, bile duct blockage, and hepatitis), seizures, or low glucose levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

GLIMEPIRIDE-1MG

Manufacturer/Marketer :

Apostle Remedies

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Glymepiz 1mg Tablet

Glymepiz 1mg Tablet is used to lower raised blood sugar levels in Type 2 diabetes mellitus. Type 2 diabetes develops if the body does not produce enough insulin or when the body's insulin does not work as well as it should.

Glymepiz 1mg Tablet contains glimepiride, which helps the pancreas release more insulin, thereby lowering blood sugar levels. Therefore, it prevents symptoms of type 2 diabetes.

Some people may experience an allergic reaction (skin rash, hives & sensitivity to sun rays), low glucose levels, nausea, headache, and shock. Most of these side effects of Glymepiz 1mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to Glymepiz 1mg Tablet. Glymepiz 1mg Tablet should not be stopped even if you feel better without consulting your doctor as the sugar level keeps changing. Glymepiz 1mg Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease or plan to get pregnant or breastfeed.

Uses of Glymepiz 1mg Tablet

Glymepiz 1mg Tablet is used in the treatment of type 2 diabetes mellitus. The detailed uses of Glymepiz 1mg Tablet are as follows:

  • Management of Type 2 Diabetes: Glymepiz 1mg Tablet helps lower blood sugar levels in individuals diagnosed with type 2 diabetes.
  • Improvement of Insulin Sensitivity: Glymepiz 1mg Tablet enhances the action of insulin, making the body's tissues more responsive to it.
  • Reduction of Cardiovascular Risks: Regular use of Glymepiz 1mg Tablet can help reduce the risk of cardiovascular diseases in diabetic patients.
  • Control of Blood Sugar Levels Post Meals: Glymepiz 1mg Tablet assists in lowering postprandial blood sugar spikes, which is beneficial for overall diabetes management.

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Directions for Use

  • Glymepiz 1mg Tablet should be taken with food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Glymepiz 1mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Key Benefits

  • Glymepiz 1mg Tablet is indicated as an adjunct to diet and exercise to improve glycaemic control in patients with type 2 diabetes.
  • It helps manage blood glucose levels in patients with diabetes and prevents diabetes-related complications like kidney damage, eye problems, and nerve issues.
  • Glimepiride stimulates cells in the pancreas that produce insulin, which helps remove sugar from the blood.

How Glymepiz 1mg Tablet Works

The Glymepiz 1mg Tablet contains Glimepiride, which acts on insulin-secreting cells called beta cells inside the pancreas and activates calcium channels on cells, allowing insulin to exit the cell. This insulin then makes each cell in the body take up glucose and utilise it, thus lowering the blood glucose. Therefore, it prevents symptoms of type 2 diabetes.

Storage

Store in a cool and dry place away from sunlight
Side effects of Glymepiz 1mg Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Glymepiz 1mg Tablet

Do not take more than the prescribed dose of Glymepiz 1mg Tablet as it may cause an overdose, leading to low blood sugar. Early signs of low blood sugar include sweating, feeling hungry, trembling or shaking, feeling confused, or having problems concentrating. If you suspect you have low blood sugar, eat or drink something that quickly increases blood sugar levels, such as fruit juice or sugar cubes. However, if your condition does not improve, please consult a doctor immediately.

Drug Warnings

  • Do not take Glymepiz 1mg Tablet if you are allergic to any of its components, if you have type 1 diabetes mellitus, diabetic ketoacidosis or diabetic coma.
  • Inform the doctor if you have liver or kidney problems, low blood sugar, or circulation problems.
  • Glymepiz 1mg Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning to become pregnant. This medicine may pass into breast milk; therefore, it should be avoided in nursing mothers.
  • Glymepiz 1mg Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Glymepiz 1mg Tablet.
  • Avoid alcohol consumption with Glymepiz 1mg Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
  • Beware of symptoms of hypoglycemia (low blood sugar), which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume candies, glucose biscuits, or honey/sugar. Make sure to carry these with you at all times, especially during long travels

Drug-Drug Interactions

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GlimepirideCinoxacin
Severe

Drug-Drug Interactions

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How does the drug interact with Glymepiz 1mg Tablet:
Co-administration of Fluconazole may increase the blood levels and effects of Glymepiz 1mg Tablet may cause low blood glucose.

How to manage the interaction:
Although there is a possible interaction, Glymepiz 1mg Tablet can be taken with fluconazole if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideCinoxacin
Severe
How does the drug interact with Glymepiz 1mg Tablet:
Co-administration of Glymepiz 1mg Tablet with Cinoxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Although there is an interaction between Glymepiz 1mg Tablet and Cinoxacin can lead to an interaction. However, consult a doctor immediately if you experience any symptoms of hyperglycemia such as increased thirst, increased hunger, and increased urination of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Glymepiz 1mg Tablet:
Co-administration of Glymepiz 1mg Tablet with Levofloxacin can affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Co-administration of Levofloxacin with Glymepiz 1mg Tablet can result in an interaction, it can be taken if a doctor has advised it. Consult the prescriber if you experience dizziness, drowsiness, headache, nervousness, confusion, tremors, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, increased urination, increased thirst, or increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Glymepiz 1mg Tablet:
Co-administration of Leflunomide may increase the blood levels and effects of Glymepiz 1mg Tablet.

How to manage the interaction:
Although there is a possible interaction, Glymepiz 1mg Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideBumetanide
Severe
How does the drug interact with Glymepiz 1mg Tablet:
Bumetanide may interfere with blood glucose control and reduce the effectiveness of Glymepiz 1mg Tablet.

How to manage the interaction:
Although there is a possible interaction, Glymepiz 1mg Tablet can be taken with bumetanide if prescribed by the doctor. Monitoring of blood glucose levels is advised.
How does the drug interact with Glymepiz 1mg Tablet:
Taking indomethacin with Glymepiz 1mg Tablet may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Glymepiz 1mg Tablet can be taken with indomethacin if prescribed by the doctor. Consult the doctor if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat.
How does the drug interact with Glymepiz 1mg Tablet:
Co-administration of Furosemide may interfere with blood glucose control and lower the effectiveness of Glymepiz 1mg Tablet.

How to manage the interaction:
Although there is a possible interaction, Glymepiz 1mg Tablet can be taken with furosemide if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Glymepiz 1mg Tablet:
Taking Glymepiz 1mg Tablet with Paroxetine may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Glymepiz 1mg Tablet can be taken with paroxetine if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideGrepafloxacin
Severe
How does the drug interact with Glymepiz 1mg Tablet:
Co-administration of Glymepiz 1mg Tablet with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Although there is a possible interaction between Glymepiz 1mg Tablet and Grepafloxacin, you can take these medicines together if prescribed by a doctor. If you experience any of these symptoms - low blood sugar, headache, dizziness, sleepiness, confusion, shaking, feeling hungry, weak, heart racing, high blood sugar, low blood sugar, serious infections, bleeding, feeling anxious, feeling sick or very thirsty - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Glymepiz 1mg Tablet:
Taking Glymepiz 1mg Tablet with sunitinib may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Glymepiz 1mg Tablet can be taken with sunitinib if prescribed by the doctor. Consult the prescriber if you experience symptoms if low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.
  • Maintain healthy body weight as obesity is also related to the onset of diabetes.
  • Maintain a low fat and a low sugar diet. Replace carbohydrates-containing foods with whole grains, fruits and vegetables, as carbohydrates turn to sugars, leading to high blood sugar.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

[ANTIDIABETICS AND ANTIHYPERGLYCEMICS]

All Substitutes & Brand Comparisons

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Alcohol

Caution

Not recommended to take Glymepiz 1mg Tablet with alcohol. Alcohol intake may increase or decrease the blood sugar lowering action of Glymepiz 1mg Tablet in an unpredictable way resulting in a harmful event.

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Pregnancy

Caution

Glymepiz 1mg Tablet is a pregnancy Category C medicine which means that there are no well-controlled studies that have been done in pregnant women. However, if you are taking Glymepiz 1mg Tablet during pregnancy, stop taking it at least 2 weeks before your due date or as prescribed by your doctor.

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Breast Feeding

Caution

Not recommended to be taken by breastfeeding mothers. Glymepiz 1mg Tablet may pass into breast milk and may cause the risk of low blood sugar in the infant. Consult your doctor for further advice.

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Driving

Caution

Not recommended in patients with fluctuating glucose levels. Glymepiz 1mg Tablet can reduce the ability to concentrate or react, if your blood sugar is lowered (hypoglycemia) or raised (hyperglycemia) or if you develop visual problems as a result of such conditions. Thus not recommended as the patient can endanger himself or others (e.g. when driving a car or using machines).

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Liver

Consult your doctor

Take Glymepiz 1mg Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

Take Glymepiz 1mg Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Glymepiz 1mg Tablet is not approved for use by a person less than 18 years old.

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Heart

Consult your doctor

Please consult your doctor before using Glymepiz 1mg Tablet if you have pre-existing heart problems. Your doctor will prescribe Glymepiz 1mg Tablet if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Glymepiz 1mg Tablet to geriatric patients. Your doctor will prescribe Glymepiz 1mg Tablet if the benefits outweigh the risks.

Country of origin

India
Other Info - GL34634

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