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Heplock Injection 2 ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Drug-Drug Interactions

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Drug-Drug Interaction: Heplock Injection 2 ml may have interaction with pain killers (salicylic acid, ibuprofen, indomethacin, phenylbutazone, and celecoxib), dextran, anti-malarial (hydroxychloroquine), blood thinner (abciximab, eptifibatide, dipyridamole), heart medicines (digitalis), antibiotic (tetracycline), nicotine, antiallergics, or blood pressure-lowering pills (nitroglycerin)

Drug-Food Interaction: Heplock Injection 2 ml may interact with alcohol. Avoid foods rich in vitamin K like coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, brussels sprouts as they may affect the working of Heplock Injection 2 ml. It is advisable to avoid smoking and use of tobacco products and nicotine as they may reduce the effectiveness of Heplock Injection 2 ml.

Drug-Disease Interaction: Use with caution in patients with bleeding problems, low platelet count (thrombocytopenia) and thrombosis (blood clot in veins).

Drug-Drug Interactions

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How does the drug interact with Heplock Injection 2 ml:
Taking Ticlopidine with Heplock Injection 2 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Heplock Injection 2 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Taking Alteplase with Heplock Injection 2 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Heplock Injection 2 ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Heplock Injection 2 ml:
When Heplock Injection 2 ml is taken with bazedoxifene the effects of Heplock Injection 2 ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Heplock Injection 2 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Taking Tenecteplase with Heplock Injection 2 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Heplock Injection 2 ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Taking Mifepristone with Heplock Injection 2 ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Heplock Injection 2 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Heplock Injection 2 ml:
Using Heplock Injection 2 ml with Oritavancin can make Heplock Injection 2 ml less effective as a therapy.

How to manage the interaction:
Heplock Injection 2 ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Heplock Injection 2 ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Taking cefdinir with Heplock Injection 2 ml may enhance the effects of Heplock Injection 2 ml by anticoagulation(preventing blood from clotting).

How to manage the interaction:
Although taking Cefdinir and Heplock Injection 2 ml can cause an interaction, it can be taken if a doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Sulfadiazine enhances the effects of Heplock Injection 2 ml by slowing its breakdown.

How to manage the interaction:
Co-administration of Sulfadiazine with Heplock Injection 2 ml can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Heplock Injection 2 ml:
Co-administration of Cangrelor with Heplock Injection 2 ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although there is a possible interaction between Heplock Injection 2 ml and Cangrelor, you can take these medicines together if prescribed by a doctor. However, if you have any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, you should seek immediate medical attention. Do not stop using any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Taking Heplock Injection 2 ml with Urokinase can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Heplock Injection 2 ml with Urokinase can result in an interaction, but it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-10IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-10IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Heplock Injection 2 ml along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Heplock Injection 2 ml.

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