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  3. Hertrust 440 Powder For Solution Combipack Injection 1's

Hertrust 440 Powder For Solution Combipack Injection 1's, Pack of 1
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Hertrust 440 Powder For Solution Combipack Injection 1's is used to treat Breast Cancer and Stomach Cancer. Hertrust 440 Powder For Solution Combipack Injection 1's contains Trastuzumab, which works by attaching itself to the HER2 proteins so that the cancer cells are no longer stimulated to grow. It also helps the body's immune system to destroy breast cancer cells. It should not be taken during pregnancy as it might cause fetal harm. Inform your doctor immediately if you are conceiving while on therapy. Advise women not to breastfeed while taking Hertrust 440 Powder For Solution Combipack Injection 1's.

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Side effects of Hertrust 440 Powder For Solution Combipack Injection
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.

Drug-Drug Interactions

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TrastuzumabBaricitinib
Severe
TrastuzumabThalidomide
Severe

Drug-Drug Interactions

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TrastuzumabBaricitinib
Severe
How does the drug interact with Hertrust 440 Powder For Solution Combipack Injection:
Coadministration of Hertrust 440 Powder For Solution Combipack Injection with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Hertrust 440 Powder For Solution Combipack Injection and Baricitinib, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.
TrastuzumabThalidomide
Severe
How does the drug interact with Hertrust 440 Powder For Solution Combipack Injection:
Taking thalidomide together with Hertrust 440 Powder For Solution Combipack Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Hertrust 440 Powder For Solution Combipack Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
TrastuzumabClozapine
Severe
How does the drug interact with Hertrust 440 Powder For Solution Combipack Injection:
Co-administration of Hertrust 440 Powder For Solution Combipack Injection and clozapine can increase the risk of toxicity.

How to manage the interaction:
Although taking Hertrust 440 Powder For Solution Combipack Injection and Clozapine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not stop using any medications without first talking to your doctor.
TrastuzumabTofacitinib
Severe
How does the drug interact with Hertrust 440 Powder For Solution Combipack Injection:
Combining Hertrust 440 Powder For Solution Combipack Injection with Tofacitinib can increase the risk of neutropenia.

How to manage the interaction:
Although there is a possible interaction between Hertrust 440 Powder For Solution Combipack Injection and Tofacitinib, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TrastuzumabInfliximab
Severe
How does the drug interact with Hertrust 440 Powder For Solution Combipack Injection:
Combining Hertrust 440 Powder For Solution Combipack Injection with Infliximab can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Hertrust 440 Powder For Solution Combipack Injection with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TrastuzumabCladribine
Severe
How does the drug interact with Hertrust 440 Powder For Solution Combipack Injection:
Combining Hertrust 440 Powder For Solution Combipack Injection with Cladribine can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Hertrust 440 Powder For Solution Combipack Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
TrastuzumabIdarubicin
Severe
How does the drug interact with Hertrust 440 Powder For Solution Combipack Injection:
Taking Hertrust 440 Powder For Solution Combipack Injection with Idarubicin can increase the risk of heart problems.

How to manage the interaction:
Co-administration of Hertrust 440 Powder For Solution Combipack Injection with Idarubicin can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience difficulty breathing, fluid retention, or chest pain, consult a doctor. Do not discontinue any medications without a doctor's advice.
TrastuzumabEtanercept
Severe
How does the drug interact with Hertrust 440 Powder For Solution Combipack Injection:
When Etanercept is used with Hertrust 440 Powder For Solution Combipack Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Hertrust 440 Powder For Solution Combipack Injection and Etanercept, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:05 AM IST

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