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Jakura 5 Tablet 60's
Jakura 5 Tablet 60's
Jakura 5 Tablet 60's
Jakura 5 Tablet 60's
Jakura 5 Tablet 60's
Jakura 5 Tablet 60's

Jakura 5 Tablet is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It contains Tofacitinib which works by lowering inflammation and symptoms associated with arthritis. In some cases, this medicine may cause side effects such as diarrhoea, headache, upper respiratory tract infection, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Health Queries

I got this 60 unit box at rs. 700 from a shop in sector 11, chandigarh. My doctor prescribed me this tablet for controlling contact dermatosis.

Ask Apollo

Ask Apollo

AI powered Health Chatbot

Jakura 5 Tablet (Tofacitinib 5mg) is prescribed to help control immune-related skin conditions like contact dermatosis by modulating the immune system’s activity.

🩺 Uses of Jakura 5 Tablet

  • It is primarily used for autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and can be used off-label for inflammatory skin conditions like contact dermatosis.
  • It works by regulating the immune response to reduce inflammation and skin symptoms.

⚕️ Mechanism of Action

  • The active ingredient, Tofacitinib, blocks Janus kinase (JAK) enzymes involved in the immune signaling pathways.
  • This inhibition reduces inflammation and immune system overactivity causing the skin condition.

🩺 Common Side Effects

  • Possible side effects include headache, diarrhea, nausea, upper respiratory tract infections (common colds), and vomiting.
  • Most side effects are mild and tend to improve with time, but persistent symptoms should be discussed with your doctor.

⚠️ Precautions and Warnings

  • Avoid if you have active infections or conditions that increase infection risk. Inform your doctor about any other immunosuppressive drugs or corticosteroids you are taking.
  • Not recommended during pregnancy, breastfeeding, or for children under 18 years due to limited safety data.
  • Regular monitoring by a specialist doctor is advised to watch for side effects or infections.

⚠️ When to Seek Medical Attention

  • Seek urgent medical care if you develop high fever, severe infections, unexplained bruising, or allergic reactions such as rash, swelling, or difficulty breathing.

Please follow your specialist doctor’s instructions closely for dosing and monitoring while taking Jakura 5 Tablet. If you experience troubling symptoms or have concerns, promptly consult your specialist.

Is there a permanent remedy for arthritis?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

There is currently no permanent cure for arthritis. Treatment focuses on relieving pain, reducing inflammation, and preserving joint function through medications, exercise, weight management, and physiotherapy. In severe cases, surgery, such as joint replacement, may improve mobility and quality of life. Early treatment can help slow disease progression and improve daily functioning.

Have a query?

Side effects of Jakura 5 Tablet
  • Practice good hygiene by washing hands frequently when touching any wounds.
  • Apply creams or lotions to the dry skin and moisturize it.
  • Wear the proper clothing and footwear when working outside.
  • Cover the wounds with bandage and change it daily.
  • Avoid baths at swimming pools, lakes and rivers.
  • Drink a lot of water to control diarrhoea and prevent dehydration.
  • Avoid spicy, fatty, or high-fiber foods that may irritate the colon.
  • Reduce stress through methods such as deep breathing or meditation.
  • Include probiotics or supplements containing live bacteria to maintain the health of the gut.
  • Quit smoking since smoking makes colitis symptoms worse.
  • See your doctor right away if you experience extreme inflammation, bleeding stools, or abdominal pain.
  • To promote overall health, drink plenty of water and consume hydrating foods like watermelon and leafy greens.
  • Support gut health with probiotic-rich foods such as yoghurt and sauerkraut.
  • Eat antioxidant-rich foods like berries and green tea, while limiting sugary drinks, alcohol, and processed foods.
  • Additionally, reduce stress through relaxation techniques like deep breathing and meditation.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.

Drug-Drug Interactions

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TofacitinibLenalidomide
Severe
TofacitinibIrinotecan
Severe

Drug-Drug Interactions

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TofacitinibLenalidomide
Severe
How does the drug interact with Jakura 5 Tablet:
Taking Jakura 5 Tablet together with lenalidomide may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction between lenalidomide and Jakura 5 Tablet, it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TofacitinibIrinotecan
Severe
How does the drug interact with Jakura 5 Tablet:
Taking Jakura 5 Tablet with Irinotecan may increase the risk of serious infection.

How to manage the interaction:
Co-administration of Jakura 5 Tablet with Irinotecan can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TofacitinibDaratumumab
Severe
How does the drug interact with Jakura 5 Tablet:
Using Jakura 5 Tablet together with daratumumab may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Jakura 5 Tablet and Daratumumab, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
TofacitinibBelimumab
Severe
How does the drug interact with Jakura 5 Tablet:
Taking Belimumab with Jakura 5 Tablet may increase the risk of infections.

How to manage the interaction:
Taking Jakura 5 Tablet with Belimumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TofacitinibAtazanavir
Severe
How does the drug interact with Jakura 5 Tablet:
Taking Jakura 5 Tablet with atazanavir may increase the blood levels of Jakura 5 Tablet. This may lead to cause severe infections.

How to manage the interaction:
Co-administration of Jakura 5 Tablet with Atazanavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
TofacitinibPemetrexed
Severe
How does the drug interact with Jakura 5 Tablet:
Taking Jakura 5 Tablet with Pemetrexed may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Pemetrexed and Jakura 5 Tablet, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
TofacitinibNilotinib
Severe
How does the drug interact with Jakura 5 Tablet:
Taking Jakura 5 Tablet with Nilotinib may increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Jakura 5 Tablet and Nilotinib, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TofacitinibInfliximab
Severe
How does the drug interact with Jakura 5 Tablet:
Combining Infliximab with Jakura 5 Tablet can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Although taking Jakura 5 Tablet and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TofacitinibSirolimus
Severe
How does the drug interact with Jakura 5 Tablet:
Coadministration of Jakura 5 Tablet with Sirolimus may increase the risk or severity of developing infection.

How to manage the interaction:
Although there is a possible interaction between Sirolimus and Jakura 5 Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TofacitinibAntithymocyte Globulin
Severe
How does the drug interact with Jakura 5 Tablet:
Using Jakura 5 Tablet together with antithymocyte globulin can increase the risk of serious infections.

How to manage the interaction:
Taking Antithymocyte Globulin with Jakura 5 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact your doctor. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consuming grapefruit products while taking Jakura 5 Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Jakura 5 Tablet, as it can lead to an interaction.

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