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Ketopat Eye Drops 5 ml is used to treat allergic eye disease. It contains Ketorolac and Olopatadine, which works by blocking the release of several chemical messengers that cause inflammation (redness and swelling), and pain in the eye. It may cause side effects such as burning sensation, eye pain, eye discomfort, eye irritation, headache, dry nose, and taste change. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Drug-Drug Interactions

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Drug-Drug Interactions: Ketopat Eye Drops 5 ml may interact with anticancer (methotrexate), blood thinner (warfarin), antiallergic (prednisolone), and medicines for arthritis- swelling in joints (dexamethasone).

Drug-Food Interactions: Consumption of alcohol while using Ketopat Eye Drops 5 ml increases the risk of dizziness. Hence avoid or limit the intake of alcohol.

Drug-Disease Interactions: Brief your doctor if you have a medical history of eye infection, asthma, and allergic reactions to Ketopat Eye Drops 5 ml and its components.

Drug-Drug Interactions

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How does the drug interact with Ketopat Eye Drops 5 ml:
Taking Ketopat Eye Drops 5 ml with aspirin can increase the risk of inflammation, bleeding, and ulceration.

How to manage the interaction:
Although there is an interaction between aspirin and Ketopat Eye Drops 5 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, or weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ketopat Eye Drops 5 ml:
Taking Ketopat Eye Drops 5 ml with piroxicam may increase the risk of inflammation, bleeding, and ulceration.

How to manage the interaction:
Although there is an interaction between piroxicam and Ketopat Eye Drops 5 ml, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ketopat Eye Drops 5 ml:
Taking Ketopat Eye Drops 5 ml with flurbiprofen can increase the risk of inflammation, bleeding, and ulceration.

How to manage the interaction:
Although there is an interaction between flurbiprofen and Ketopat Eye Drops 5 ml, it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness contact a doctor immediately. Do not discontinue any medications without first consulting a doctor.
How does the drug interact with Ketopat Eye Drops 5 ml:
Taking Ketopat Eye Drops 5 ml with celecoxib can increase the risk of inflammation, bleeding, and ulceration.

How to manage the interaction:
Although there is an interaction between Ketopat Eye Drops 5 ml and celecoxib, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ketopat Eye Drops 5 ml:
Taking Ketopat Eye Drops 5 ml with citalopram can increase the risk of bleeding complications.

How to manage the interaction:
Although there is an interaction between Ketopat Eye Drops 5 ml and citalopram, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ketopat Eye Drops 5 ml:
Coadministration of Ketopat Eye Drops 5 ml and tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Ketopat Eye Drops 5 ml and tenofovir alafenamide, it can be taken if advised by a doctor. However, if you experience nausea, vomiting, less desire to eat, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, or confusion, contact with a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ketopat Eye Drops 5 ml:
Taking sodium oxybate with Ketopat Eye Drops 5 ml may increase the side effects.

How to manage the interaction:
Although there is an interaction between Ketopat Eye Drops 5 ml and sodium oxybate, they can be taken together if prescribed by a doctor. However, if you experience drowsiness, dizziness, lightheadedness, confusion, and impairment in thinking, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ketopat Eye Drops 5 ml:
Coadministration of Ketopat Eye Drops 5 ml and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Ketopat Eye Drops 5 ml and leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ketopat Eye Drops 5 ml:
Co-administration Ketopat Eye Drops 5 ml and apixaban may raise the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Ketopat Eye Drops 5 ml and apixaban, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, or weakness. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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KETOROLAC-0.4%W/V+OLOPATADINE-0.1%W/VFruit juices, Fruits
Moderate

Drug-Food Interactions

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KETOROLAC-0.4%W/V+OLOPATADINE-0.1%W/VFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Coadministration of Ketopat Eye Drops 5 ml along with grapefruit or grapefruit juice may increase the blood levels of Ketopat Eye Drops 5 ml. This may increase the risk and/or severity of side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, and yellowing of the skin or eyes. Avoid the consumption of grapefruit juice with Ketopat Eye Drops 5 ml, as it can increase the risk of side effects.

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