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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lexanox Plus Oral Paste is used to treat canker sores, also called aphthous ulcers in the mouth. Mouth ulcers are small, painful lesions that develop in the mouth or at the base of the gums. It contains Amlexanox and Lidocaine, which work by blocking the chemical messengers that cause pain, redness and inflammation due to mouth ulcers. It forms a protective film over the ulcer and fastens healing. This medicine may sometimes cause side effects such as reaction to the application site, such as a slight burning or stinging sensation.

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Drug-Drug Interactions

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LidocaineSaquinavir
Critical
LidocaineArbutamine
Critical

Drug-Drug Interactions

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LidocaineSaquinavir
Critical
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with Saquinavir can increase the blood levels of Lexanox Plus Oral Paste, 5 gm and cause an irregular heart rhythm.

How to manage the interaction:
Taking Lexanox Plus Oral Paste, 5 gm with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
LidocaineArbutamine
Critical
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Lexanox Plus Oral Paste, 5 gm with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineNitroprusside
Severe
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Co-administration of Lexanox Plus Oral Paste, 5 gm with Nitroprusside may rarely cause methemoglobinemia (a blood disorder in which little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Lexanox Plus Oral Paste, 5 gm and Nitroprusside can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like discoloration of the skin, headache, dizziness, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting your doctor.
LidocaineIopamidol
Severe
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm and Iopamidol may increase the risk of causing seizures(fits).

How to manage the interaction:
Although taking Lexanox Plus Oral Paste, 5 gm and Iopamidol together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Rasburicase with Lexanox Plus Oral Paste, 5 gm can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasburicase with Lexanox Plus Oral Paste, 5 gm can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Flutamide with Lexanox Plus Oral Paste, 5 gm can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Lexanox Plus Oral Paste, 5 gm and Flutamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking isosorbide dinitrate with Lexanox Plus Oral Paste, 5 gm may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide dinitrate and Lexanox Plus Oral Paste, 5 gm together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineDofetilide
Severe
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm together with Dofetilide can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
There may be a possibility of interaction between Lexanox Plus Oral Paste, 5 gm and Dofetilide, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without first consulting your doctor.
LidocaineMetrizamide
Severe
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm and Metrizamide may increase the risk of causing seizures(fits).

How to manage the interaction:
Although taking Lexanox Plus Oral Paste, 5 gm and Metrizamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LidocaineAmprenavir
Severe
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with Amprenavir may increase the blood levels of Lexanox Plus Oral Paste, 5 gm, which increases severe side effects.

How to manage the interaction:
There may be a possibility of interaction between Lexanox Plus Oral Paste, 5 gm and Amprenavir, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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