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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lexanox Plus Oral Paste is used to treat canker sores, also called aphthous ulcers in the mouth. Mouth ulcers are small, painful lesions that develop in the mouth or at the base of the gums. It contains Amlexanox and Lidocaine, which work by blocking the chemical messengers that cause pain, redness and inflammation due to mouth ulcers. It forms a protective film over the ulcer and fastens healing. This medicine may sometimes cause side effects such as reaction to the application site, such as a slight burning or stinging sensation.

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Drug-Drug Interactions

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LidocaineArbutamine
Critical
LidocaineSaquinavir
Critical

Drug-Drug Interactions

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LidocaineArbutamine
Critical
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Lexanox Plus Oral Paste, 5 gm with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineSaquinavir
Critical
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with Saquinavir can increase the blood levels of Lexanox Plus Oral Paste, 5 gm and cause an irregular heart rhythm.

How to manage the interaction:
Taking Lexanox Plus Oral Paste, 5 gm with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
LidocaineNitroprusside
Severe
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Co-administration of Lexanox Plus Oral Paste, 5 gm with Nitroprusside may rarely cause methemoglobinemia (a blood disorder in which little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Lexanox Plus Oral Paste, 5 gm and Nitroprusside can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like discoloration of the skin, headache, dizziness, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with Cyclophosphamide may increase the risk of methemoglobinemia (a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Although there is a possible interaction, cyclophosphamide can be taken with Lexanox Plus Oral Paste, 5 gm if prescribed by the doctor. However, consult the doctor if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue the medication without consulting a doctor.
LidocaineAmyl nitrite
Severe
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with Amyl nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Lexanox Plus Oral Paste, 5 gm and Amyl nitrite, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineAmprenavir
Severe
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with Amprenavir may increase the blood levels of Lexanox Plus Oral Paste, 5 gm, which increases severe side effects.

How to manage the interaction:
There may be a possibility of interaction between Lexanox Plus Oral Paste, 5 gm and Amprenavir, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with Bupivacaine may cause serious side effects including methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells), brain related problems and heart problems.

How to manage the interaction:
There may be a possibility of interaction between Lexanox Plus Oral Paste, 5 gm and Bupivacaine, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop pale, gray, or blue colored skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Taking Lexanox Plus Oral Paste, 5 gm with bupropion can increase the risk of seizures(fits).

How to manage the interaction:
Co-administration of bupropion along with Lexanox Plus Oral Paste, 5 gm can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Coadministration of metoclopramide with Lexanox Plus Oral Paste, 5 gm may increase the risk of methemoglobinemia(a blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between metoclopramide and Lexanox Plus Oral Paste, 5 gm, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as grey discolouration of the skin, nausea, headache, dizziness, weakness, breathing difficulty, rapid or shallow breathing, palpitation, anxiety, and confusion, consult a doctor. Do not stop using medications without a doctor's advice.
How does the drug interact with Lexanox Plus Oral Paste, 5 gm:
Coadministration of Ifosfamide with Lexanox Plus Oral Paste, 5 gm can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Ifosfamide and Lexanox Plus Oral Paste, 5 gm, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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