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సంఘటన :
మెథోట్రెక్సేట్-10ఎంజి
తయారీదారు/మార్కెటర్ :
రీజెనిక్స్ డ్రగ్స్ లిమిటెడ్
వినియోగ రకం :
నోటి ద్వారా
రిటర్న్ పాలసీ :
రిటర్న్ చేయబడదు
ఇప్పటి నుండి చెల్లుబాటు అవుతుంది :
Jan-27
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Drug-Drug Interactions
MethotrexateEtretinate
Critical
Severe
Drug-Drug Interactions
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MethotrexateEtretinate
Critical
How does the drug interact with Metrotrex 5 Tablet:
Co-administration of Etretinate with Metrotrex 5 Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Metrotrex 5 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Co-administration of Etretinate with Metrotrex 5 Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Metrotrex 5 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Metrotrex 5 Tablet:
Coadministration of leflunomide with Metrotrex 5 Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Although there is an interaction between leflunomide and Metrotrex 5 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of leflunomide with Metrotrex 5 Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Although there is an interaction between leflunomide and Metrotrex 5 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Metrotrex 5 Tablet:
Taking deferasirox with Metrotrex 5 Tablet may increase the risk of kidney damage.
How to manage the interaction:
Although there is a possible interaction between deferasirox and Metrotrex 5 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Taking deferasirox with Metrotrex 5 Tablet may increase the risk of kidney damage.
How to manage the interaction:
Although there is a possible interaction between deferasirox and Metrotrex 5 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Metrotrex 5 Tablet:
Coadministration of Metrotrex 5 Tablet with ibuprofen can increase the effect and side effects of Metrotrex 5 Tablet.
How to manage the interaction:
Although there is a possible interaction between Metrotrex 5 Tablet and ibuprofen, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Coadministration of Metrotrex 5 Tablet with ibuprofen can increase the effect and side effects of Metrotrex 5 Tablet.
How to manage the interaction:
Although there is a possible interaction between Metrotrex 5 Tablet and ibuprofen, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateNitrous oxide
Severe
How does the drug interact with Metrotrex 5 Tablet:
Combine use of nitrous oxide with Metrotrex 5 Tablet may increase the levels and side effects of nitrous oxide.
How to manage the interaction:
Although there is a possible interaction between nitrous oxide and Metrotrex 5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, pale skin, easy bruising or bleeding, unusual weakness, mouth sores, black or bloody stools, and decreased urine output, consult the doctor. Do not discontinue any medications without doctors advice.
Combine use of nitrous oxide with Metrotrex 5 Tablet may increase the levels and side effects of nitrous oxide.
How to manage the interaction:
Although there is a possible interaction between nitrous oxide and Metrotrex 5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, pale skin, easy bruising or bleeding, unusual weakness, mouth sores, black or bloody stools, and decreased urine output, consult the doctor. Do not discontinue any medications without doctors advice.
Severe
How does the drug interact with Metrotrex 5 Tablet:
Taking tacrolimus with Metrotrex 5 Tablet may increase the risk of kidney problems.
How to manage the interaction:
Although there is a possible interaction between tacrolimus and Metrotrex 5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting to a doctor.
Taking tacrolimus with Metrotrex 5 Tablet may increase the risk of kidney problems.
How to manage the interaction:
Although there is a possible interaction between tacrolimus and Metrotrex 5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting to a doctor.
How does the drug interact with Metrotrex 5 Tablet:
Coadministration of Tenofovir disoproxil with Metrotrex 5 Tablet may increase the levels and side effects of Tenofovir disoproxil.
How to manage the interaction:
Although there is a possible interaction between tenofovir disoproxil and Metrotrex 5 Tablet, you can take these medicines when prescribed by your doctor. However, if you experience any symptoms such as vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, breathing difficulty, or dizziness, consult your doctor. Do not stop using any medications without consulting a doctor.
Coadministration of Tenofovir disoproxil with Metrotrex 5 Tablet may increase the levels and side effects of Tenofovir disoproxil.
How to manage the interaction:
Although there is a possible interaction between tenofovir disoproxil and Metrotrex 5 Tablet, you can take these medicines when prescribed by your doctor. However, if you experience any symptoms such as vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, breathing difficulty, or dizziness, consult your doctor. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Metrotrex 5 Tablet:
Coadministration of trimethoprim with Metrotrex 5 Tablet can increase the risk or severity of blood disorders.
How to manage the interaction:
Although there is a possible interaction between trimethoprim and Metrotrex 5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
Coadministration of trimethoprim with Metrotrex 5 Tablet can increase the risk or severity of blood disorders.
How to manage the interaction:
Although there is a possible interaction between trimethoprim and Metrotrex 5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
MethotrexateNafcillin
Severe
How does the drug interact with Metrotrex 5 Tablet:
Coadministration of Metrotrex 5 Tablet with nafcillin can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between nafcillin and Metrotrex 5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, nausea, vomiting, mouth ulcers, sore throat, body aches, or other flu-like symptoms, consult the doctor.
Coadministration of Metrotrex 5 Tablet with nafcillin can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between nafcillin and Metrotrex 5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, nausea, vomiting, mouth ulcers, sore throat, body aches, or other flu-like symptoms, consult the doctor.
How does the drug interact with Metrotrex 5 Tablet:
Taking Human immunoglobulin with Metrotrex 5 Tablet may increase the risk or severity of kidney problems.
How to manage the interaction:
Taking Human immunoglobulin with Metrotrex 5 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Taking Human immunoglobulin with Metrotrex 5 Tablet may increase the risk or severity of kidney problems.
How to manage the interaction:
Taking Human immunoglobulin with Metrotrex 5 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
METHOTREXATE-5MGCaffeine containing foods/drinks
Moderate
Drug-Food Interactions
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METHOTREXATE-5MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Caffeine may reduce the effectiveness of Metrotrex 5 Tablet. Avoid taking caffeine while taking Metrotrex 5 Tablet. This can increase the risk or severity of side effects.
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Caffeine may reduce the effectiveness of Metrotrex 5 Tablet. Avoid taking caffeine while taking Metrotrex 5 Tablet. This can increase the risk or severity of side effects.
మద్యం
అసురక్షితం
Metrotrex 5 Tablet 10's తీసుకుంటున్నప్పుడు మద్యం సేవించకుండా ఉండాలని సిఫార్సు చేయబడింది.
గర్భం
అసురక్షితం
Metrotrex 5 Tablet 10's తీవ్రమైన పుట్టుకతో వచ్చే లోపాలకు కారణం కావచ్చు. మీరు గర్భవతిగా ఉన్నప్పుడు Metrotrex 5 Tablet 10's తీసుకోవాలని సిఫార్సు చేయబడలేదు.
తల్లిపాలు ఇవ్వడం
అసురక్షితం
Metrotrex 5 Tablet 10's తల్లిపాలలోకి వెళుతుంది. Metrotrex 5 Tablet 10'sతో చికిత్స పొందుతున్నప్పుడు తల్లిపాలు ఇవ్వడం మానుకోండి.
డ్రైవింగ్
జాగ్రత్త
Metrotrex 5 Tablet 10's మైకము మరియు అలసటకు కారణం కావచ్చు; మీరు ఈ లక్షణాలను అనుభవిస్తే డ్రైవ్ చేయవద్దు లేదా భారీ యంత్రాలను నడపవద్దు.
కాలేయం
జాగ్రత్త
మీకు దీర్ఘకాలిక కాలేయ వ్యాధి ఉంటే Metrotrex 5 Tablet 10's తీసుకోవద్దు. Metrotrex 5 Tablet 10's తీసుకునే ముందు మీకు కాలేయ బలహీనత ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
కిడ్నీ
జాగ్రత్త
Metrotrex 5 Tablet 10's తీసుకునే ముందు మీకు కిడ్నీ బలహీనత ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
పిల్లలు
జాగ్రత్త
వైద్యుడు సూచించినట్లయితే మాత్రమే పిల్లలలో Metrotrex 5 Tablet 10's జాగ్రత్తగా ఉపయోగించాలి.
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