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సంఘటన :
మెథోట్రెక్సేట్-10ఎంజి
తయారీదారు/మార్కెటర్ :
రీజెనిక్స్ డ్రగ్స్ లిమిటెడ్
వినియోగ రకం :
నోటి ద్వారా
రిటర్న్ పాలసీ :
రిటర్న్ చేయబడదు
ఇప్పటి నుండి చెల్లుబాటు అవుతుంది :
జనవరి-27
Drug-Drug Interactions
MethotrexateEtretinate
Critical
Severe
Drug-Drug Interactions
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MethotrexateEtretinate
Critical
How does the drug interact with Trexodat 10mg Tablet:
Co-administration of Etretinate with Trexodat 10mg Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Trexodat 10mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Co-administration of Etretinate with Trexodat 10mg Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Trexodat 10mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Trexodat 10mg Tablet:
Co-administration of Trexodat 10mg Tablet with Indomethacin can increase the levels and side effects of Trexodat 10mg Tablet.
How to manage the interaction:
Although there is a possible interaction between Trexodat 10mg Tablet and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms like mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), infection, as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Co-administration of Trexodat 10mg Tablet with Indomethacin can increase the levels and side effects of Trexodat 10mg Tablet.
How to manage the interaction:
Although there is a possible interaction between Trexodat 10mg Tablet and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms like mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), infection, as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Severe
How does the drug interact with Trexodat 10mg Tablet:
Co-administration of Meloxicam with Trexodat 10mg Tablet may increase the levels and side effects of Meloxicam.
How to manage the interaction:
Although there is a possible interaction between meloxicam and Trexodat 10mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
Co-administration of Meloxicam with Trexodat 10mg Tablet may increase the levels and side effects of Meloxicam.
How to manage the interaction:
Although there is a possible interaction between meloxicam and Trexodat 10mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Trexodat 10mg Tablet:
Taking deferasirox with Trexodat 10mg Tablet may increase the risk of kidney damage.
How to manage the interaction:
Although there is a possible interaction between deferasirox and Trexodat 10mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Taking deferasirox with Trexodat 10mg Tablet may increase the risk of kidney damage.
How to manage the interaction:
Although there is a possible interaction between deferasirox and Trexodat 10mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Trexodat 10mg Tablet:
Co-administration of Trexodat 10mg Tablet with cloxacillin can increase the risk or severity of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between cloxacillin and Trexodat 10mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, Consult a doctor. Do not stop using any medications without consulting to a doctor.
Co-administration of Trexodat 10mg Tablet with cloxacillin can increase the risk or severity of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between cloxacillin and Trexodat 10mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, Consult a doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Trexodat 10mg Tablet:
Coadministration of Trexodat 10mg Tablet with piroxicam can increase the levels and side effects.
How to manage the interaction:
Although there is a possible interaction between piroxicam and Trexodat 10mg Tablet, it can be taken if prescribed by a doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
Coadministration of Trexodat 10mg Tablet with piroxicam can increase the levels and side effects.
How to manage the interaction:
Although there is a possible interaction between piroxicam and Trexodat 10mg Tablet, it can be taken if prescribed by a doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Trexodat 10mg Tablet:
Co-administration of Trexodat 10mg Tablet with etanercept can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between etanercept and Trexodat 10mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, and pain or burning during urination, Consult a doctor. Do not stop using any medications without consulting a doctor.
Co-administration of Trexodat 10mg Tablet with etanercept can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between etanercept and Trexodat 10mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, and pain or burning during urination, Consult a doctor. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Trexodat 10mg Tablet:
Coadministration of leflunomide with Trexodat 10mg Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Although there is an interaction between leflunomide and Trexodat 10mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of leflunomide with Trexodat 10mg Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Although there is an interaction between leflunomide and Trexodat 10mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MethotrexateNitrous oxide
Severe
How does the drug interact with Trexodat 10mg Tablet:
Combine use of nitrous oxide with Trexodat 10mg Tablet may increase the levels and side effects of nitrous oxide.
How to manage the interaction:
Although there is a possible interaction between nitrous oxide and Trexodat 10mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, pale skin, easy bruising or bleeding, unusual weakness, mouth sores, black or bloody stools, and decreased urine output, consult the doctor. Do not discontinue any medications without doctors advice.
Combine use of nitrous oxide with Trexodat 10mg Tablet may increase the levels and side effects of nitrous oxide.
How to manage the interaction:
Although there is a possible interaction between nitrous oxide and Trexodat 10mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, pale skin, easy bruising or bleeding, unusual weakness, mouth sores, black or bloody stools, and decreased urine output, consult the doctor. Do not discontinue any medications without doctors advice.
Severe
How does the drug interact with Trexodat 10mg Tablet:
Co-administration of Trexodat 10mg Tablet with aspirin can increase the levels and side effects of Trexodat 10mg Tablet.
How to manage the interaction:
Although there is a possible interaction between aspirin and Trexodat 10mg Tablet, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience symptoms such as nausea, vomiting, diarrhea, sore throat, chills, fever, rash, unusual bruising or bleeding, pale skin, dark urine, swelling of the legs and hands, breathing difficulty. Do not stop using any medications without consulting a doctor.
Co-administration of Trexodat 10mg Tablet with aspirin can increase the levels and side effects of Trexodat 10mg Tablet.
How to manage the interaction:
Although there is a possible interaction between aspirin and Trexodat 10mg Tablet, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience symptoms such as nausea, vomiting, diarrhea, sore throat, chills, fever, rash, unusual bruising or bleeding, pale skin, dark urine, swelling of the legs and hands, breathing difficulty. Do not stop using any medications without consulting a doctor.
Drug-Food Interactions
METHOTREXATE-10MGCaffeine containing foods/drinks
Moderate
Drug-Food Interactions
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METHOTREXATE-10MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Caffeine may reduce the effectiveness of Trexodat 10mg Tablet. Avoid taking caffeine while taking Trexodat 10mg Tablet. This can increase the risk or severity of side effects.
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Caffeine may reduce the effectiveness of Trexodat 10mg Tablet. Avoid taking caffeine while taking Trexodat 10mg Tablet. This can increase the risk or severity of side effects.
Product Substitutes
మద్యం
అసురక్షితం
ట్రెక్సోడాట్ 10ఎంజి టాబ్లెట్ తీసుకుంటున్నప్పుడు మద్యం సేవించకుండా ఉండాలని సిఫార్సు చేయబడింది.
గర్భం
అసురక్షితం
ట్రెక్సోడాట్ 10ఎంజి టాబ్లెట్ తీవ్రమైన పుట్టుకతో వచ్చే లోపాలకు కారణం కావచ్చు. మీరు గర్భవతిగా ఉన్నప్పుడు ట్రెక్సోడాట్ 10ఎంజి టాబ్లెట్ తీసుకోవాలని సిఫార్సు చేయబడలేదు.
తల్లిపాలు ఇవ్వడం
అసురక్షితం
ట్రెక్సోడాట్ 10ఎంజి టాబ్లెట్ తల్లిపాలలోకి వెళుతుంది. ట్రెక్సోడాట్ 10ఎంజి టాబ్లెట్తో చికిత్స పొందుతున్నప్పుడు తల్లిపాలు ఇవ్వడం మానుకోండి.
డ్రైవింగ్
జాగ్రత్త
ట్రెక్సోడాట్ 10ఎంజి టాబ్లెట్ మైకము మరియు అలసటకు కారణం కావచ్చు; మీరు ఈ లక్షణాలను అనుభవిస్తే డ్రైవ్ చేయవద్దు లేదా భారీ యంత్రాలను నడపవద్దు.
కాలేయం
జాగ్రత్త
మీకు దీర్ఘకాలిక కాలేయ వ్యాధి ఉంటే ట్రెక్సోడాట్ 10ఎంజి టాబ్లెట్ తీసుకోవద్దు. ట్రెక్సోడాట్ 10ఎంజి టాబ్లెట్ తీసుకునే ముందు మీకు కాలేయ బలహీనత ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
కిడ్నీ
జాగ్రత్త
ట్రెక్సోడాట్ 10ఎంజి టాబ్లెట్ తీసుకునే ముందు మీకు కిడ్నీ బలహీనత ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
పిల్లలు
జాగ్రత్త
వైద్యుడు సూచించినట్లయితే మాత్రమే పిల్లలలో ట్రెక్సోడాట్ 10ఎంజి టాబ్లెట్ జాగ్రత్తగా ఉపయోగించాలి.
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