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Zycolchin Tablet 10's
Zycolchin Tablet 10's
Zycolchin Tablet 10's
Zycolchin Tablet 10's
Zycolchin Tablet 10's

Zycolchin Tablet is used to prevent and treat gout attacks and relieve the pain of gout attacks. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, and cardiovascular death. The medicine helps control symptoms but does not cure the underlying condition, so it should be taken exactly as prescribed by a doctor.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Health Queries

My uric acid level is 7.3 mg/dL. I have not been taking any medication because I did not have gout attacks or pain earlier, but recently I have started experiencing foot pain. Can uric acid be lowered without medication, and is treatment lifelong once started?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

A uric acid level of 7.3 mg/dL is mildly elevated. Lifestyle changes such as reducing high-purine foods like red meat, alcohol, and sugary drinks, staying well hydrated, and maintaining a healthy weight may help lower it. If treatment is needed, it may have to be continued long-term depending on your risk of gout and recurrent high uric acid levels.

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Side effects of Zycolchin Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink plenty of fluids and stay hydrated.
  • Avoid foods containing sugars, salts and processed food.
  • Avoid consumption of alcohol.
  • Take healthy diet containing fiber, carbohydrates and lean proteins.
  • Exercise regularly and maintain a healthy lifestyle.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.

Drug-Drug Interactions

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ColchicineItraconazole
Critical
ColchicineDarunavir
Critical

Drug-Drug Interactions

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ColchicineItraconazole
Critical
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet with itraconazole may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Zycolchin Tablet with itraconazole can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ColchicineDarunavir
Critical
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet with darunavir may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Taking Zycolchin Tablet with Darunavir is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ColchicineClarithromycin
Critical
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet with clarithromycin may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Taking Zycolchin Tablet with Clarithromycin is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ColchicineKetoconazole
Critical
How does the drug interact with Zycolchin Tablet:
Using Zycolchin Tablet together with ketoconazole may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Ketoconazole with Zycolchin Tablet is not recommended as it can cause an interaction, they can be taken if prescribed by a doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without consulting a doctor
ColchicineAmiodarone
Severe
How does the drug interact with Zycolchin Tablet:
Coadministration of amiodarone with Zycolchin Tablet may increase the Zycolchin Tablet levels, leading to an increased risk or severity of side effects.

How to manage the interaction:
Taking amiodarone and Zycolchin Tablet together can lead to an interaction, but they can be taken together if your doctor has advised it. However, consult a doctor if you experience abdominal discomfort, diarrhoea, fever, muscle pain, tiredness, weakness, and numbness or tingling in your hands and feet. Do not discontinue any medications without consulting a doctor.
ColchicinePropafenone
Severe
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet and propafenone may increase the blood levels of Zycolchin Tablet, increasing the risk of side effects.

How to manage the interaction:
Although taking Zycolchin Tablet and Propafenone together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting your doctor.
ColchicineLomitapide
Severe
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet and lomitapide may increase the blood levels of Zycolchin Tablet to dangerous level, increasing the risk of serious side effects.

How to manage the interaction:
Although there is a possible interaction between Zycolchin Tablet and Lomitapide, you can take these medicines together if prescribed by your doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ColchicineCarvedilol
Severe
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet with Carvedilol increases Zycolchin Tablet levels in the blood, leading to increased side effects.

How to manage the interaction:
Although taking Zycolchin Tablet and Carvedilol together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, if you experience any symptoms like vomiting, stomach pain, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.
ColchicineAtorvastatin
Severe
How does the drug interact with Zycolchin Tablet:
coadministration of atorvastatin with Zycolchin Tablet can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of atorvastatin with Zycolchin Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, diarrhea, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet, consult the doctor. Do not stop using any medications without talking to a doctor.
ColchicineSaquinavir
Severe
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet and saquinavir may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Zycolchin Tablet and Saquinavir together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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COLCHICINE-0.5MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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COLCHICINE-0.5MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming excessive quantities of grapefruit juice can raise the levels of Zycolchin Tablet in your blood, increasing the risk of side effects. Avoid the consumption of grapefruit juice while taking Zycolchin Tablet.

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