FLOXIP TZ TABLET

Manufacturer : PIR-PIRAMAL I LTD.
Composition : CIPROFLOXACIN-500MG+TINIDAZOLE-600MG
Dose Form : TABLET
Description : FLOXIP TZ TAB
Route Of Administration : ORAL
Pack : 10
₹26.73
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SKU
FLO0045

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Manufacturer : PIR-PIRAMAL I LTD.
Composition : CIPROFLOXACIN-500MG+TINIDAZOLE-600MG
Dose Form : TABLET
Description : FLOXIP TZ TAB
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information

CIPROFLOXACIN-500MG+TINIDAZOLE-600MG

CIPROFLOXACIN

Information for patients
Drug Information Ciprofloxacin is an antibiotic belonging to the fluoroquinolone family. The active substance is ciprofloxacin. Ciprofloxacin works by killing bacteria that cause infections. It only works with specific strains of bacteria. Adults Ciprofloxacin is used in adults to treat the following bacterial infections: respiratory tract infections long lasting or recurring ear or sinus infections urinary tract infections infections of the testicles genital organ infections in women gastro-intestinal tract infections and intra-abdominal infections skin and soft tissue infections bone and joint infections to treat infections in patients with a very low white blood cell count (neutropenia) to prevent infections in patients with a very low white blood cell count (neutropenia) to prevent infections due to the bacterium Neisseria meningitidis anthrax inhalation exposure If you have a severe infection or one that is caused by more than one type of bacterium, you may be given additional antibiotic treatment in addition to Ciprofloxacin. Children and adolescents Ciprofloxacin is used in children and adolescents, under specialist medical supervision, to treat the following bacterial infections: lung and bronchial infections in children and adolescents suffering from cystic fibrosis complicated urinary tract infections, including infections that have reached the kidneys (pyelonephritis) anthrax inhalation exposure Ciprofloxacin may also be used to treat other specific severe infections in children and adolescents when your doctor considered this necessary
Drug Alert
Alert allergic (hypersensitive) to the active substance, to other quinolone drugs or to any of the other ingredients of Ciprofloxacin (see section 6) taking tizanidine
Before Consuming the Medicine
Avoid Drug allergic (hypersensitive) to the active substance, to other quinolone drugs or to any of the other ingredients of Ciprofloxacin (see section 6) taking tizanidine
Drug Special Care Tell your doctor if you: have ever had kidney problems because your treatment may need to be adjusted suffer from epilepsy or other neurological conditions have a history of tendon problems during previous treatment with antibiotics such as Ciprofloxacin have myasthenia gravis (a type of muscle weakness) have a history of abnormal heart rhythms (arrythmias)
Drug Drug Interactions Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including any that you obtained without a prescription. Do not take Ciprofloxacin together with tizanidine, because this may cause side effects such as low blood pressure and sleepiness (see Section 2: "Do not take Ciprofloxacin"). The following medicines are known to interact with Ciprofloxacin in your body. Taking Ciprofloxacin together with these medicines can influence the therapeutic effect of those medicines. It can also increase the probability of experiencing side effects. Tell your doctor if you are taking: warfarin or other oral anti-coagulants (to thin the blood) probenecid (for gout) methotrexate (for certain types of cancer, psoriasis, rheumatoid arthritis) theophylline (for breathing problems) tizanidine (for muscle spasticity in multiple sclerosis) clozapine (an antipsychotic) ropinirole (for Parkinson’s disease) phenytoin (for epilepsy) Ciprofloxacin may increase the levels of the following medicines in your blood: pentoxifylline (for circulatory disorders) caffeine Some medicines reduce the effect of Ciprofloxacin. Tell your doctor if you take or wish to take: antacids mineral supplements sucralfate a polymeric phosphate binder (e.g. sevelamer) medicines or supplements containing calcium, magnesium, aluminium or iron If these preparations are essential, take Ciprofloxacin about two hours before or no sooner than four hours after them.
Drug Pregnancy Interaction It is preferable to avoid the use of Ciprofloxacin during pregnancy. Tell your doctor if you are planning to get pregnant
Drug Breast feeding Interaction Do not take Ciprofloxacin during breast feeding because ciprofloxacin is excreted in breast milk and can be harmful for your child
Drug Machinery Interaction Ciprofloxacin may make you feel less alert. Some neurological adverse events can occur. Therefore, make sure you know how you react to Ciprofloxacin before driving a vehicle or operating machinery. If in doubt, talk to your doctor
Drug More Information Unless you take Ciprofloxacin during meals, do not eat or drink any dairy products (such as milk or yoghurt) or drinks with added calcium when you take the tablets, as they may affect the absorption of the active substance
How to take the Medicine
Consumption Info Your doctor will explain to you exactly how much Ciprofloxacin you will have to take as well as how often and for how long. This will depend on the type of infection you have and how bad it is. Tell your doctor if you suffer from kidney problems because your dose may need to be adjusted
Drug quanitty The treatment usually lasts from 5 to 21 days, but may take longer for severe infections. Take the tablets exactly as your doctor has told you. Ask your doctor or pharmacist if you are not sure how many tablets to take and how to take Ciprofloxacin
Drug Dose The treatment usually lasts from 5 to 21 days, but may take longer for severe infections. Take the tablets exactly as your doctor has told you. Ask your doctor or pharmacist if you are not sure how many tablets to take and how to take Ciprofloxacin
Excess Drug Consumption If you take more than the prescribed dose, get medical help immediately. If possible, take your tablets or the box with you to show the doctor
Forgot Drug Consumption Take the normal dose as soon as possible and then continue as prescribed. However, if it is almost time for your next dose, do not take the missed dose and continue as usual. Do not take a double dose to make up for a forgotten dose. Be sure to complete your course of treatment
Stop Drug Consumption It is important that you finish the course of treatment even if you begin to feel better after a few days. If you stop taking this medicine too soon, your infection may not be completely cured and the symptoms of the infection may return or get worse. You might also develop resistance to the antibiotic
Possible Side Effects
General Information Like all medicines, Ciprofloxacin can cause side effects, although not everybody gets them. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, tell your doctor or pharmacist
Common Drug Side Effects nausea, diarrhoea joint pains in children
Rare Drug Side Effects inflammation of the bowel (colitis) linked to antibiotic use (can be fatal in very rare cases) (see Section 2: Take special care with Ciprofloxacin) changes to the blood count (leukopenia, leukocytosis, neutropenia, anaemia), increased or decreased amounts of a blood clotting factor (thrombocytes) allergic reaction, swelling (oedema), or rapid swelling of the skin and mucous membranes (angio- oedema) increased blood sugar (hyperglycaemia) confusion, disorientation, anxiety reactions, strange dreams, depression, or hallucinations pins and needles, unusual sensitivity to stimuli of the senses, decreased skin sensitivity, tremors, seizures (see Section 2: Take special care with Ciprofloxacin), or giddiness eyesight problems tinnitus, loss of hearing, impaired hearing rapid heartbeat (tachycardia) expansion of blood vessels (vasodilation), low blood pressure, or fainting shortness of breath, including asthmatic symptoms liver disorders, jaundice (cholestatic icterus), or hepatitis sensitivity to light (see Section 2: Take special care with Ciprofloxacin) muscle pain, inflammation of the joints, increased muscle tone, or cramp kidney failure, blood or crystals in the urine (see Section 2: Take special care with Ciprofloxacin), urinary tract inflammation fluid retention or excessive sweating abnormal levels of a clotting factor (prothrombin) or increased levels of the enzyme amylase
Very Rare Drug Side Effects a special type of reduced red blood cell count (haemolytic anaemia); a dangerous drop in a type of white blood cells (agranulocytosis ); a drop in the number of red and white blood cells and platelets (pancytopenia), which may be fatal; and bone marrow depression, which may also be fatal (see Section 2: Take special care with Ciprofloxacin) severe allergic reactions (anaphylactic reaction or anaphylactic shock, which can be fatal - serum sickness) (see Section 2: Take special care with Ciprofloxacin) mental disturbances (psychotic reactions) (see Section 2: Take special care with Ciprofloxacin) migraine, disturbed coordination, unsteady walk (gait disturbance), disorder of sense of smell (olfactory disorders), pressure on the brain (intracranial pressure) visual colour distortions inflammation of the wall of the blood vessels (vasculitis) pancreatitis death of liver cells (liver necrosis) very rarely leading to life-threatening liver failure small, pin-point bleeding under the skin (petechiae); various skin eruptions or rashes (for example, the potentially fatal Stevens-Johnson syndrome or toxic epidermal necrolysis) muscle weakness, tendon inflammation, tendon rupture – especially of the large tendon at the back of the ankle (Achilles tendon) (see Section 2: Take special care with Ciprofloxacin); worsening of the symptoms of myasthenia gravis (see Section 2: Take special care with Ciprofloxacin) troubles associated with the nervous system such as pain, burning, tingling, numbness and/or weakness in extremities severe cardiac rhythm abnormalities, irregular heart beat (Torsades de Pointes)
Drug Side Effects Symptoms fungal superinfections a high concentration of eosinophils, a type of white blood cell loss of appetite (anorexia) hyperactivity or agitation headache, dizziness, sleeping problems, or taste disorders vomiting, abdominal pain, digestive problems such as stomach upset (indigestion/heartburn), or wind increased amounts of certain substances in the blood (transaminases and/or bilirubin) rash, itching, or hives joint pain in adults poor kidney function pains in your muscles and bones, feeling unwell (asthenia), or fever increase in blood alkaline phosphatase (a certain substance in the blood)
How to Store the Medicine
How to Store the Medicine Keep out of the reach and sight of children. Do not use Ciprofloxacin after the expiry date, which is stated on the blister and carton after “EXP”: The expiry date refers to the last day of that month. This medicinal product does not require any special storage conditions. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

TINIDAZOLE

Information for patients
Drug Information Tinidazole is an anti-infective agent. It is used to treat a variety of bacterial infections including: infections of the skin, blood, chest, lung, genitals or womb lining.an infection associated with stomach ulcers in combination with other drugs. infections caused by organisms called protozoa, such as amoebiasis and giardiasis (stomach infections) and trichomoniasis (a genital infection). vaginal infections (vaginitis) and gum infections (gingivitis). It is also used before certain surgical operations to prevent bacterial infections developing. You should ask your doctor if you are unsure why you have been given Tinidazole.
Drug Alert
Alert you are allergic (hypersensitive) to tinidazole or any similar drugs or to any of the other ingredients listed in section 6. An allergic reaction could cause itching, a skin rash or wheezing. you are in the first 13 weeks of pregnancy or trying to become pregnant. you are breast feeding. you have a blood disorder or a history of blood disorders. you have central nervous system (CNS) disease, including epilepsy.
Before Consuming the Medicine
Avoid Drug you are allergic (hypersensitive) to tinidazole or any similar drugs or to any of the other ingredients listed in section 6. An allergic reaction could cause itching, a skin rash or wheezing. you are in the first 13 weeks of pregnancy or trying to become pregnant. you are breast feeding. you have a blood disorder or a history of blood disorders. you have central nervous system (CNS) disease, including epilepsy.
Drug Special Care You should not drink wine, beer or spirits during treatment and for 3 days after stopping treatment with Tinidazole. The combination may cause flushing, stomach cramps, vomiting (being sick) and palpitations (pounding heart). You should take Tinidazole during or after a meal.
Drug Drug Interactions You should always tell your doctor if you are taking or have recently taken any other medicines including those obtained without a prescription. You should tell your doctor if you are currently taking blood thinners such as warfarin to prevent blood clots as your doctor may wish to monitor you more closely
Drug Pregnancy Interaction You should not take Tinidazole if you are in the first 13 weeks of pregnancy or are trying to become pregnant. Always ask your doctor or pharmacist for advice before taking Tinidazole or any other medicine.
Drug Breast feeding Interaction You should not take Tinidazole if you are breast feeding as small amounts can pass into your milk. If you stop breast-feeding during treatment you should not start again until atleast 3 days after stopping Tinidazole.
Drug Machinery Interaction Do not drive or use machinery if Tinidazole makes you feel drowsy or gives you problems with co-ordination or sensation (e.g. numbness or weakness).
Drug More Information no data available
How to take the Medicine
Consumption Info Children under 12 years For bacterial infections, Tinidazole is not recommended for use in children less than 12 years as it has not been tested in this age group. For protozoal infections, Tinidazole can be used in children and has not been shown to cause any different side effects or more problems than it does in adults. The dose and length of treatment depends upon the infection being treated. If you are on dialysis, your doctor may prescribe a different dose. The doses most commonly used for the different infections are shown in the table below: For treating the infection associated with stomach ulcers: The usual dose is 1 tablet (500mg) taken twice a day. Your doctor will probably prescribe two other medicines to be taken with Tinidazole. Treatment with the three medicines together will usually be for 1 week. For treating most bacterial infections: The usual dose is 4 tablets (2g) on the first day then 2 tablets (1g) once a day or 1 tablet (500mg) twice a day. The usual length of treatment is 5 to 6 days. For treating bacterial vaginitis (a vaginal infection) and acute ulcerative gingivitis (a gum infection): The usual dose is 4 tablets (2g) given as a single dose. For vaginitis you may be given 4 tablets (2g) on two consecutive days. For preventing bacterial infections after surgery: Usually 4 tablets (2g) are given as a single dose about 12 hours before surgery. For treating protozoal infections: For treating intestinal amoebiasis (a stomach infection) Adult The usual dose is 4 tablets (2g) once a day for 2 to 3 days. Child The usual dose is 50 to 60mg/kg of body weight once a day for 3 days. For treating amoebic involvement of the liver (a liver infection): Adult The usual dose is 3 to 4 tablets (1.5 to 2g) once a day for 3 to 6 days. Child The usual dose is 50 to 60mg/kg of body weight once a day for 5 days. For treating giardiasis (an abdominal infection) and trichomoniasis (an infection of the sex organs in males and females): Adult The usual dose is 4 tablets (2g) given as a single dose. Child The usual dose is 50 to-75mg/kg of body weight given as a single dose.
Drug quanitty Always take your tablets exactly as your doctor has told you and as written on the label on the pack. Check with your doctor or pharmacist if you are not sure.
Drug Dose Take Tinidazole with a glass of water during or after a meal. Swallow the tablets whole. It is best to take the medicine at the same time each day. Your doctor will calculate the dose required for a child and may repeat the dose once if the infection has not cleared up completely
Excess Drug Consumption If you take too much Tinidazole tell your doctor or contact your nearest hospital casualty department immediately. Take any remaining tablets with you.
Forgot Drug Consumption If you forget to take Tinidazole take it as soon as you can. Take your next dose at the right time. Do not take a double dose to make up for a forgotten dose.
Stop Drug Consumption If you stop taking Tinidazole too soon, the infection may return. Take Tinidazole for the full time of treatment, even when you begin to feel better. If you have any further questions about the use of this product, ask your doctor or pharmacist for advice.
Possible Side Effects
General Information Like all medicines Tinidazole may cause side effects, although not everybody gets them. Tell your doctor immediately if you experience any of the following symptoms after taking this medicine.
Common Drug Side Effects The most common side effects that occur in people taking Tinidazole are listed below. These may go away during treatment as your body adjusts to the medicine. Tell your doctor if any of these side effects continue to bother you. nausea (feeling sick) or vomiting, loss of appetite, diarrhoea, stomach pain or cramps headache or tiredness furry tongue or unpleasant metallic taste dark urine Tinidazole can sometimes cause a temporary reduction in white blood cells which does not usually give you any symptoms.
Rare Drug Side Effects dizziness or vertigo numbness, tingling, pain or weakness in hands or feet clumsiness or unsteadiness fits or seizures fever or chills and painful ulcers in the mouth or bottom (rectum) sore or swollen mouth redness of the face or neck.
Very Rare Drug Side Effects Sudden wheeziness, difficulty in breathing, swelling of eyelids, face or lips or tongue, rash or itching (especially affecting the whole body).
Drug Side Effects Symptoms If any of the side effects gets serious or you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
How to Store the Medicine
How to Store the Medicine Keep all medicines out of the reach and sight of children. Do not take this medicine after the expiry date stamped on the pack after EXP. The expiry date refers to the last day of that month. Do not store above 25°C. Store in the original package to protect from light. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

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