Advagraf 0.5 mg Capsule का उपयोग, फायदे ,साइड इफेक्ट,कीमत in Hindi

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Composition:टैक्रोलिमस-5एमजी

Prescription Medicine

Advagraf 0.5 mg Capsule is used to prevent rejection of a transplanted organ, such as a liver, kidney, or heart. It contains Tacrolimus, which works by suppressing the activity of T and B lymphocytes (cells in the immune system) that usually attack foreign invaders and defend the body against foreign cells and infection. Thus, it prevents organ rejection in transplanted patients and helps the body to accept the new organ.

Written By Veda Maddala , M Pharmacy

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

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More about the Product

``` :संरचना :

टैक्रोलिमस-5एमजी

निर्माता/विपणनकर्ता :

मायलन फार्मास्युटिकल्स प्राइवेट लिमिटेड

सेवन का प्रकार :

मौखिक

वापसी नीति :

वापसी योग्य नहीं

Advagraf 0.5 mg Capsule 10's के बारे में

Advagraf 0.5 mg Capsule 10's का उपयोग लीवर, किडनी या हृदय जैसे प्रत्यारोपित अंग की अस्वीकृति को रोकने के लिए किया जाता है। अंग अस्वीकृति तब होती है जब रोगी की प्रतिरक्षा प्रणाली दाता अंग को विदेशी के रूप में पहचानती है और उसे खत्म करने की कोशिश करती है।

Advagraf 0.5 mg Capsule 10's में टैक्रोलिमस होता है, जो टी और बी लिम्फोसाइट्स (प्रतिरक्षा प्रणाली में कोशिकाएं) की गतिविधि को दबाकर काम करता है जो आम तौर पर विदेशी आक्रमणकारियों पर हमला करते हैं और विदेशी कोशिकाओं और संक्रमण से शरीर की रक्षा करते हैं। इस प्रकार, यह प्रत्यारोपित रोगियों में अंग अस्वीकृति को रोकता है और शरीर को नया अंग स्वीकार करने में मदद करता है।

Advagraf 0.5 mg Capsule 10's को डॉक्टर के बताए अनुसार लें। आपको सलाह दी जाती है कि Advagraf 0.5 mg Capsule 10's का उपयोग तब तक करें जब तक आपके डॉक्टर ने आपकी चिकित्सा स्थिति के आधार पर आपके लिए इसकी सिफारिश की है। कुछ लोगों को मतली, दस्त, सिरदर्द, गुर्दे की समस्या, संक्रमण, बुखार, कब्ज या उच्च रक्तचाप का अनुभव हो सकता है। Advagraf 0.5 mg Capsule 10's के इन दुष्प्रभावों में से अधिकांश को चिकित्सीय ध्यान देने की आवश्यकता नहीं होती है और धीरे-धीरे समय के साथ हल हो जाते हैं। हालांकि, अगर साइड इफेक्ट बने रहते हैं या बिगड़ते हैं, तो कृपया अपने डॉक्टर से सलाह लें।

यदि आपको टैक्रोलिमस या किसी अन्य दवा से एलर्जी है, तो कृपया अपने डॉक्टर को बताएं। यदि आप गर्भवती हैं या स्तनपान कराने वाली माँ हैं, तो Advagraf 0.5 mg Capsule 10's का उपयोग करने से पहले डॉक्टर से परामर्श करने की सलाह दी जाती है। Advagraf 0.5 mg Capsule 10's के साथ शराब के सेवन से बचें। केवल तभी गाड़ी चलाएँ जब आप सतर्क हों, क्योंकि Advagraf 0.5 mg Capsule 10's कुछ लोगों में दृष्टि समस्याओं या तंत्रिका संबंधी गड़बड़ी पैदा कर सकता है। यदि आप टीका लगवाने वाली हैं, तो Advagraf 0.5 mg Capsule 10's लेने से पहले अपने डॉक्टर को सूचित करें। Advagraf 0.5 mg Capsule 10's संक्रमण या त्वचा कैंसर के खतरे को बढ़ा सकता है क्योंकि यह शरीर की प्रतिरक्षा रक्षा प्रणाली को कम करता है।

Advagraf 0.5 mg Capsule 10's के उपयोग

Advagraf 0.5 mg Capsule 10's का उपयोग प्रत्यारोपित अंग अस्वीकृति की रोकथाम के लिए किया जाता है

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उपयोग के लिए निर्देश

कैप्सूल: कैप्सूल को डॉक्टर की सलाह के अनुसार लें। इसे पूरा पानी के साथ निगल लें; इसे कुचलें, तोड़ें या चबाएं नहीं। दाने: दानेदार बनाने के लिए दानों को पानी में मिलाना चाहिए। तैयार सस्पेंशन तुरंत पिएं। बाद में उपयोग के लिए निलंबन को न बचाएं।

औषधीय लाभ

Advagraf 0.5 mg Capsule 10's में टैक्रोलिमस होता है, जो एक इम्यूनोसप्रेसेन्ट है जिसका उपयोग प्रत्यारोपण के बाद अंग अस्वीकृति को रोकने के लिए किया जाता है। Advagraf 0.5 mg Capsule 10's टी और बी लिम्फोसाइट्स (प्रतिरक्षा प्रणाली में कोशिकाएं) की गतिविधि को दबा देता है जो आम तौर पर विदेशी आक्रमणकारियों पर हमला करते हैं और विदेशी कोशिकाओं और संक्रमण से शरीर की रक्षा करते हैं। नतीजतन, यह शरीर को नया अंग स्वीकार करने में मदद करता है और उन रोगियों में अंग अस्वीकृति को रोकता है जिनके अंग प्रत्यारोपण हुए हैं।

भंडारण

धूप से दूर ठंडी और सूखी जगह पर रखें

Side effects of Advagraf 0.5 mg Capsule

Swelling In The Feet And Ankles

Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
Gently massage the swollen area with firm but not painful pressure.
Keep the swollen area clean and moisturized to prevent injury and infection.
Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.

Chest Pain

Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
Take rest and refrain from doing physical activity for a while, and restart after a few days.
Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

दवा चेतावनी

कृपया अपने डॉक्टर को बताएं कि क्या आपको टैक्रोलिमस या अन्य दवाओं से एलर्जी है। यदि आप गर्भवती हैं या स्तनपान कराने वाली माँ हैं, तो Advagraf 0.5 mg Capsule 10's का उपयोग करने से पहले डॉक्टर से परामर्श करने की सलाह दी जाती है। Advagraf 0.5 mg Capsule 10's के साथ शराब के सेवन से बचें। केवल तभी गाड़ी चलाएँ जब आप सतर्क हों, क्योंकि Advagraf 0.5 mg Capsule 10's कुछ लोगों में दृष्टि समस्याओं या तंत्रिका संबंधी गड़बड़ी पैदा कर सकता है। यदि आप टीका लगवाने वाली हैं, तो Advagraf 0.5 mg Capsule 10's लेने से पहले अपने डॉक्टर को सूचित करें। Advagraf 0.5 mg Capsule 10's संक्रमण या त्वचा कैंसर के खतरे को बढ़ा सकता है क्योंकि यह शरीर की प्रतिरक्षा रक्षा प्रणाली को कम करता है। Advagraf 0.5 mg Capsule 10's लेते समय, आपको सलाह दी जाती है कि बाहर जाते समय सुरक्षात्मक कपड़े और सनस्क्रीन पहनें। आपको मौखिक निलंबन तैयार करने के लिए कांच या धातु सामग्री का उपयोग करने की अनुशंसा की जाती है। निलंबन तैयार करने के लिए प्लास्टिक (पीवीसी) सामग्री का उपयोग करने से बचें, क्योंकि दाने प्लास्टिक के कंटेनर से चिपक जाएंगे, और हो सकता है कि आपके बच्चे को उसकी पूरी खुराक न मिले। साँस न लें या दानों या तैयार मौखिक निलंबन को अपनी त्वचा या आँखों के संपर्क में न आने दें। त्वचा के आकस्मिक संपर्क के मामले में, क्षेत्र को साबुन और पानी से अच्छी तरह धो लें, और अगर यह आंखों के संपर्क में आता है, तो सादे पानी से धो लें।

Drug-Drug Interactions

TacrolimusMifepristone

Critical

TacrolimusZiprasidone

Critical

Drug-Drug Interactions

TacrolimusMifepristone

Critical

How does the drug interact with Advagraf 0.5 mg Capsule:
Taking Advagraf 0.5 mg Capsule with Mifepristone may significantly increase the blood levels of Advagraf 0.5 mg Capsule, which may increase the risk and/or severity of side effects.

How to manage the interaction:
Taking Advagraf 0.5 mg Capsule with Mifepristone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.

TacrolimusZiprasidone

Critical

How does the drug interact with Advagraf 0.5 mg Capsule:
Taking Advagraf 0.5 mg Capsule with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Advagraf 0.5 mg Capsule with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

TacrolimusSaquinavir

Critical

How does the drug interact with Advagraf 0.5 mg Capsule:
Taking Advagraf 0.5 mg Capsule with saquinavir can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Advagraf 0.5 mg Capsule with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

TacrolimusCidofovir

Critical

How does the drug interact with Advagraf 0.5 mg Capsule:
Taking cidofovir with Advagraf 0.5 mg Capsule can increase the risk of kidney problems.

How to manage the interaction:
Taking Advagraf 0.5 mg Capsule with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor immediately if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.

TacrolimusThioridazine

Critical

How does the drug interact with Advagraf 0.5 mg Capsule:
Combining Advagraf 0.5 mg Capsule with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Advagraf 0.5 mg Capsule with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

TacrolimusDronedarone

Critical

How does the drug interact with Advagraf 0.5 mg Capsule:
Taking Advagraf 0.5 mg Capsule with dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Advagraf 0.5 mg Capsule with Dronedarone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

TacrolimusNelfinavir

Severe

How does the drug interact with Advagraf 0.5 mg Capsule:
Taking Advagraf 0.5 mg Capsule with nelfinavir may significantly increase the blood levels of Advagraf 0.5 mg Capsule, which may lead to severe side effects such as infections, high sugars, kidney problems, high blood pressure, heart problems and hyperkalemia(high potassium levels in blood).

How to manage the interaction:
Although taking Advagraf 0.5 mg Capsule and nelfinavir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

TacrolimusGatifloxacin

Severe

How does the drug interact with Advagraf 0.5 mg Capsule:
Taking Advagraf 0.5 mg Capsule together with gatifloxacin can increase the risk of an irregular heart rhythm and can lead to other side effects.

How to manage the interaction:
Although taking Advagraf 0.5 mg Capsule and gatifloxacin together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.

TacrolimusAmiodarone

Severe

How does the drug interact with Advagraf 0.5 mg Capsule:
Coadministration of Amiodarone with Advagraf 0.5 mg Capsule can lead to or increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Amiodarone with Advagraf 0.5 mg Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without first consulting a doctor.

TacrolimusIbuprofen

Severe

How does the drug interact with Advagraf 0.5 mg Capsule:
Taking Advagraf 0.5 mg Capsule and ibuprofen can cause kidney problems.

How to manage the interaction:
Co-administration of Advagraf 0.5 mg Capsule and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

TACROLIMUS-0.5MGGrapefruit and Grapefruit Juice

Moderate

Drug-Food Interactions

TACROLIMUS-0.5MGGrapefruit and Grapefruit Juice

Moderate

Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking of grapefruit or grapefruit juice while on Advagraf 0.5 mg Capsule treatment may lead to increased Advagraf 0.5 mg Capsule levels in blood. Avoid or limit grapefruit or grapefruit juice intake during treatment with Advagraf 0.5 mg Capsule.

आहार और जीवनशैली सलाह```

OUTPUT:

Include fruits and vegetables in your daily routine.
Follow a vitamin-C-rich diet.
Reduce salt intake.
Eat a handful of walnuts and almonds every day.
Reduce intake of unhealthy cholesterol and fats.
Consume dark chocolate with at least 70% cocoa.

Liver and Heart transplant:

Eat whole-grain bread, cereals and other grains, fruits and vegetables, lean meats, fish and poultry.
Maintain a low-fat and low-salt diet.
Drink low-fat milk or eat other low-fat dairy products to maintain adequate calcium.
Stay hydrated by drinking sufficient water and other fluids.
Avoid alcohol consumption.
Avoid grapefruit and grapefruit juice.

आदत बनाने वाला

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शराब

असुरक्षित

Advagraf 0.5 mg Capsule 10's के साथ शराब के सेवन से बचें क्योंकि इससे साइड इफेक्ट का खतरा बढ़ सकता है। Advagraf 0.5 mg Capsule 10's के साथ शराब का सेवन करने से पहले कृपया डॉक्टर से सलाह लें।

गर्भावस्था

सावधानी

गर्भावस्था के दौरान टैक्रोलिमस का उपयोग करने से किडनी की शिथिलता या नवजात हाइपरकेलेमिया (रक्त में पोटेशियम का उच्च स्तर) हो सकता है। इसलिए, कृपया डॉक्टर से सलाह लें यदि आप गर्भवती हैं Advagraf 0.5 mg Capsule 10's लेने से पहले और यदि आप प्रसव उम्र की महिला हैं, तो Advagraf 0.5 mg Capsule 10's का उपयोग करते समय प्रभावी गर्भनिरोधक विधियों का उपयोग करें।

स्तनपान

अपने डॉक्टर से सलाह लें

Advagraf 0.5 mg Capsule 10's स्तन के दूध में उत्सर्जित हो सकता है। इसलिए, कृपया अपने डॉक्टर को सूचित करें यदि आप Advagraf 0.5 mg Capsule 10's लेने से पहले स्तनपान कराने वाली माँ हैं। Advagraf 0.5 mg Capsule 10's के साथ इलाज के दौरान आपको स्तनपान कराने से बचना चाहिए या स्तनपान कराने से बचना चाहिए।

ड्राइविंग

सावधानी

Advagraf 0.5 mg Capsule 10's कुछ लोगों में दृष्टि समस्याओं या तंत्रिका संबंधी गड़बड़ का कारण बन सकता है। इसलिए, Advagraf 0.5 mg Capsule 10's लेने के बाद यदि आपको इनमें से कोई भी लक्षण दिखाई दे तो गाड़ी चलाने से बचें।

लीवर

अपने डॉक्टर से सलाह लें

Advagraf 0.5 mg Capsule 10's लेने से पहले कृपया डॉक्टर से सलाह लें यदि आपको लीवर की बीमारियाँ/स्थितियाँ हैं।

गुर्दा

अपने डॉक्टर से सलाह लें

Advagraf 0.5 mg Capsule 10's लेने से पहले कृपया डॉक्टर से सलाह लें यदि आपको किडनी की बीमारियाँ/स्थितियाँ हैं।

बच्चे

निर्धारित होने पर सुरक्षित

बच्चों में Advagraf 0.5 mg Capsule 10's का उपयोग केवल डॉक्टर द्वारा बताई गई खुराक में ही किया जाना चाहिए।

उत्पत्ति देश

भारत

निर्माता/विपणनकर्ता पता

Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7Th To 12Th Floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103.

Other Info - ADV0042

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Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Oct 14, 2025 | 1:05 PM IST

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Advagraf 0.5 mg Capsule 10's