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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Alkem Dexa 4 Injection 2 ml contains dexamethasone, which is used to treat severe allergic conditions, collagen diseases, pulmonary disorders, blood disorders, rheumatic diseases, skin diseases, gastrointestinal disorders, etc. This medicine belongs to the corticosteroid class, which works by inhibiting the production of certain chemical messengers in the body that cause inflammation. Thus, it helps reduce swelling, redness, and itching.

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Drug-Drug Interactions

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DexamethasoneRilpivirine
Critical

Drug-Drug Interactions

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How does the drug interact with Alkem Dexa 4 Injection 2 ml:
When Regorafenib is taken with Alkem Dexa 4 Injection 2 ml, may significantly reduce the blood levels of Regorafenib.

How to manage the interaction:
Co-administration of Regorafenib and Alkem Dexa 4 Injection 2 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
DexamethasoneRilpivirine
Critical
How does the drug interact with Alkem Dexa 4 Injection 2 ml:
When Rilpivirine is taken with Alkem Dexa 4 Injection 2 ml, may significantly reduce the blood levels of Rilpivirine.

How to manage the interaction:
Co-administration of Rilpivirine and Alkem Dexa 4 Injection 2 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Alkem Dexa 4 Injection 2 ml:
Co-administration of Desmopressin with Alkem Dexa 4 Injection 2 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Alkem Dexa 4 Injection 2 ml and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Alkem Dexa 4 Injection 2 ml:
When Alkem Dexa 4 Injection 2 ml is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine and Alkem Dexa 4 Injection 2 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Alkem Dexa 4 Injection 2 ml:
Taking lemborexant with Alkem Dexa 4 Injection 2 ml may reduce the blood levels of lemborexant, which may make the medication less effective in treating your condition.

How to manage the interaction:
Taking Lemborexant with Alkem Dexa 4 Injection 2 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Alkem Dexa 4 Injection 2 ml:
Taking Alkem Dexa 4 Injection 2 ml with Leflunomide may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Alkem Dexa 4 Injection 2 ml can be taken with Leflunomide if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Alkem Dexa 4 Injection 2 ml:
Taking Alkem Dexa 4 Injection 2 ml and Tolvaptan together may possibly reduce the effects of Tolvaptan.

How to manage the interaction:
Although taking Alkem Dexa 4 Injection 2 ml and tolvaptan together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue the medication without consulting a doctor.
DexamethasoneVoclosporin
Severe
How does the drug interact with Alkem Dexa 4 Injection 2 ml:
When Alkem Dexa 4 Injection 2 ml is taken with Voclosporin, may reduce the blood levels of Voclosporin.

How to manage the interaction:
Co-administration of Alkem Dexa 4 Injection 2 ml with Voclosporin can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having symptoms, let your doctor know right away. They can recommend other options that won't cause any problems. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Alkem Dexa 4 Injection 2 ml:
Alkem Dexa 4 Injection 2 ml and Ofloxacin co-administration can result in tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture.

How to manage the interaction:
Taking Ofloxacin with Alkem Dexa 4 Injection 2 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Alkem Dexa 4 Injection 2 ml:
Taking Ciprofloxacin with Alkem Dexa 4 Injection 2 ml may cause tendinitis(a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture(an injury that is usually painful and likely to affect your ability to walk).

How to manage the interaction:
Although there is an interaction between Alkem Dexa 4 Injection 2 ml and Ciprofloxacin, but can be taken together if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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DEXAMETHASONE-4MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEXAMETHASONE-4MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking Alkem Dexa 4 Injection 2 ml with Caffeine may increase the side effects of Alkem Dexa 4 Injection 2 ml. Avoid consuming caffeine while taking Alkem Dexa 4 Injection 2 ml.

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