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Dexon 4 mg Injection contains dexamethasone, which is used to treat severe allergic conditions, collagen diseases, pulmonary disorders, blood disorders, rheumatic diseases, skin diseases, gastrointestinal disorders, etc. This medicine belongs to the corticosteroid class, which works by inhibiting the production of certain chemical messengers in the body that cause inflammation. Thus, it helps reduce swelling, redness, and itching.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions: Dexon 4 mg Injection may interact with nonsteroidal anti-inflammatory drugs (e.g. aspirin), anticonvulsants (e.g. phenytoin), sedative-hypnotic medications (e.g. phenobarbital, primidone), antibiotics (e.g. rifampicin, rifabutin), anticancer (e.g. aminoglutethimide), anticoagulant (e.g. warfarin), antiretroviral drugs (e.g. ritonavir, darunavir), and medicines used to treat epilepsy, pain and manic depression (e.g. carbamazepine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: If you ever had fungal infections, epilepsy, schizophrenia, amoebiasis, myasthenia gravis, peptic ulcer, osteoporosis, psychoses, eye infections, glaucoma, mental conditions, diabetes, TB, bacteraemia (viable bacteria in the bloodstream), joint, liver, kidney, or heart conditions and septic arthritis resulting from gonorrhoea or tuberculosis or have or had a recent vaccination inform your doctor before taking Dexon 4 mg Injection.

DexamethasoneRilpivirine
Critical

Drug-Drug Interactions

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DexamethasoneRilpivirine
Critical
How does the drug interact with Dexon 4 mg Injection 30 ml:
When Rilpivirine is taken with Dexon 4 mg Injection 30 ml, may significantly reduce the blood levels of Rilpivirine.

How to manage the interaction:
Co-administration of Rilpivirine and Dexon 4 mg Injection 30 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexon 4 mg Injection 30 ml:
When Dexon 4 mg Injection 30 ml is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine and Dexon 4 mg Injection 30 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexon 4 mg Injection 30 ml:
When Regorafenib is taken with Dexon 4 mg Injection 30 ml, may significantly reduce the blood levels of Regorafenib.

How to manage the interaction:
Co-administration of Regorafenib and Dexon 4 mg Injection 30 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexon 4 mg Injection 30 ml:
Co-administration of Desmopressin with Dexon 4 mg Injection 30 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Dexon 4 mg Injection 30 ml and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexon 4 mg Injection 30 ml:
Taking Dexon 4 mg Injection 30 ml may reduce the blood levels of Dasatinib, making the medication less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction, Dexon 4 mg Injection 30 ml can be taken with Dasatinib if prescribed by the doctor. In case of any unusual side effects, consult a doctor. Do not discontinue the medication without consulting a doctor.
DexamethasoneToremifene
Severe
How does the drug interact with Dexon 4 mg Injection 30 ml:
When Toremifene is taken with Dexon 4 mg Injection 30 ml, may reduce the effectiveness of Toremifene.

How to manage the interaction:
There may be a possibility of interaction between Dexon 4 mg Injection 30 ml and Toremifene, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dexon 4 mg Injection 30 ml:
Co-administration of Bempedoic acid with Dexon 4 mg Injection 30 ml can result in tendinitis (a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although there is an interaction, Bempedoic acid can be taken with Dexon 4 mg Injection 30 ml if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb, stop taking bempedoic acid and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dexon 4 mg Injection 30 ml:
Taking Ciprofloxacin with Dexon 4 mg Injection 30 ml may cause tendinitis(a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture(an injury that is usually painful and likely to affect your ability to walk).

How to manage the interaction:
Although there is an interaction between Dexon 4 mg Injection 30 ml and Ciprofloxacin, but can be taken together if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb. Do not discontinue the medication without consulting a doctor.
DexamethasoneVoclosporin
Severe
How does the drug interact with Dexon 4 mg Injection 30 ml:
When Dexon 4 mg Injection 30 ml is taken with Voclosporin, may reduce the blood levels of Voclosporin.

How to manage the interaction:
Co-administration of Dexon 4 mg Injection 30 ml with Voclosporin can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having symptoms, let your doctor know right away. They can recommend other options that won't cause any problems. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dexon 4 mg Injection 30 ml:
Taking Dexon 4 mg Injection 30 ml with Mifepristone may significantly reduce the levels of Dexon 4 mg Injection 30 ml, which may make Dexon 4 mg Injection 30 ml less effective in treating your condition.

How to manage the interaction:
Co-administration of Dexon 4 mg Injection 30 ml with mifepristone can cause an interaction. However, they can be taken together if prescribed by the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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DEXAMETHASONE-4MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEXAMETHASONE-4MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking Dexon 4 mg Injection 30 ml with Caffeine may increase the side effects of Dexon 4 mg Injection 30 ml. Avoid consuming caffeine while taking Dexon 4 mg Injection 30 ml.

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