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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Apiza 0.5 Md Tablet is used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. It may also be used to treat restless leg syndrome. It contains clonazepam, which works by increasing the level of a calming chemical in the brain. This helps relieve anxiety and seizures (fits). It also helps relax the tense muscles. Thereby, it aids in the treatment of seizures, panic disorder, and involuntary muscle spasms. In some cases, it may cause side effects such as drowsiness, dizziness, fatigue, and problems with memory, walking, and coordination. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Side effects of Apiza 0.5 Md Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
ClonazepamHydrocodone
Severe

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
How does the drug interact with Apiza 0.5 Md Tablet:
Taking Apiza 0.5 Md Tablet with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Apiza 0.5 Md Tablet and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamHydrocodone
Severe
How does the drug interact with Apiza 0.5 Md Tablet:
Co-administration of Apiza 0.5 Md Tablet with Hydrocodone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Apiza 0.5 Md Tablet with Hydrocodone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Apiza 0.5 Md Tablet:
Co-administration of Apiza 0.5 Md Tablet with Tramadol may significantly lead to adverse effects such as respiratory difficulties (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Apiza 0.5 Md Tablet and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamPethidine
Severe
How does the drug interact with Apiza 0.5 Md Tablet:
Combining Meperidine with Apiza 0.5 Md Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Pethidine with Apiza 0.5 Md Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Apiza 0.5 Md Tablet:
When Apiza 0.5 Md Tablet and Ketamine are taken together, may increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Ketamine and Apiza 0.5 Md Tablet, but it can be taken if prescribed by a doctor. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamRemifentanil
Severe
How does the drug interact with Apiza 0.5 Md Tablet:
Co-administration of Remifentanil with Apiza 0.5 Md Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Apiza 0.5 Md Tablet with Remifentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Apiza 0.5 Md Tablet:
Co-administration of Butorphanol with Apiza 0.5 Md Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking Apiza 0.5 Md Tablet and Butorphanol together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamHydromorphone
Severe
How does the drug interact with Apiza 0.5 Md Tablet:
Co-administration of Apiza 0.5 Md Tablet with Hydromorphone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Apiza 0.5 Md Tablet with Hydromorphone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Apiza 0.5 Md Tablet:
Using Morphine together with Apiza 0.5 Md Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Morphine with Apiza 0.5 Md Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like shortness of breath, feeling tired, having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Apiza 0.5 Md Tablet:
Co-administration of fentanyl and Apiza 0.5 Md Tablet can increase the risk of side effects.

How to manage the interaction:
Although combining Fentanyl and Apiza 0.5 Md Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you feel sleepiness, loss of balance, or confusion. Do not stop taking any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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