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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Axepine MD 2 Tablet is an atypical antipsychotic medicine used to treat various mood disorders, including schizophrenia, acute manic and mixed episodes associated with Bipolar I disorder, irritability related to autism spectrum disorder, Tourette’s disorder, and as an add-on (adjunctive) treatment for major depressive disorder (MDD). Axepine MD 2 Tablet contains Aripiprazole, which works by restoring the balance of dopamine and serotonin in the brain that influences mood, behaviour, and thinking. By doing so, it helps relieve symptoms of various mood and behavioural disorders. Common side effects of Axepine MD 2 Tablet in adults may include nausea, dizziness, vomiting, anxiety, constipation, trouble sleeping, headache, restlessness, blurred vision, and cold-like symptoms. In children, common side effects can include sleepiness, insomnia, headache, nausea, vomiting, nasal congestion, tiredness, weight changes, changes in appetite, restlessness, tremors, drooling, and muscle stiffness. Most side effects are mild and go away over time, but consult your doctor if they persist or worsen.

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Side effects of Axepine MD 2 Tablet
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.

Drug-Drug Interactions

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AripiprazoleOxycodone
Severe

Drug-Drug Interactions

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How does the drug interact with Axepine MD 2 Tablet:
Co-administration of Metoclopramide with Axepine MD 2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Axepine MD 2 Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AripiprazoleOxycodone
Severe
How does the drug interact with Axepine MD 2 Tablet:
Using Axepine MD 2 Tablet together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Axepine MD 2 Tablet with Oxycodone together can result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
How does the drug interact with Axepine MD 2 Tablet:
Taking carbamazepine and Axepine MD 2 Tablet together can reduce the effects of Axepine MD 2 Tablet which may make the medication less effective.

How to manage the interaction:
Taking carbamazepine and Axepine MD 2 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Axepine MD 2 Tablet:
Coadministration of Axepine MD 2 Tablet and primidone may decrease the blood levels of Axepine MD 2 Tablet, which may make Axepine MD 2 Tablet less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between primidone and Axepine MD 2 Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AripiprazoleFosphenytoin
Severe
How does the drug interact with Axepine MD 2 Tablet:
When Axepine MD 2 Tablet and Fosphenytoin are taken together, can reduce the levels of Axepine MD 2 Tablet levels in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Axepine MD 2 Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Axepine MD 2 Tablet:
Using Morphine together with Axepine MD 2 Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Morphine with Axepine MD 2 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without consulting a doctor.
AripiprazoleHydromorphone
Severe
How does the drug interact with Axepine MD 2 Tablet:
Using Axepine MD 2 Tablet together with Hydromorphone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Axepine MD 2 Tablet and Hydromorphone together can cause an interaction, it can be taken if a doctor has suggested it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Axepine MD 2 Tablet:
Using Axepine MD 2 Tablet together with Fentanyl can cause central nervous system depression (a condition that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Axepine MD 2 Tablet with Fentanyl together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - trouble breathing, feeling tired, or difficulty concentrating - contact a doctor immediately. Do not stop using any medications without a doctor's advice.
AripiprazoleAlfentanil
Severe
How does the drug interact with Axepine MD 2 Tablet:
Using Axepine MD 2 Tablet together with Alfentanil can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Axepine MD 2 Tablet and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
AripiprazoleIopamidol
Severe
How does the drug interact with Axepine MD 2 Tablet:
Coadministration of Axepine MD 2 Tablet and Iopamidol may increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although taking Axepine MD 2 Tablet and Iopamidol together can cause an interaction, it can be taken if a doctor has suggested it. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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