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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Azafect Injection 100 ml is used to treat Myelodysplastic syndrome, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. It contains Azacitidine, a nucleoside metabolic inhibitor which works by preventing cancer cells from growing. It incorporates into the genetic material of the cells and interferes with the production of new DNA and RNA. This helps correct problems with the maturation and growth of young blood cells in the bone marrow, which causes myelodysplastic disorders.

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Whats That

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निर्माता/विपणक :

मेट्टा लाइफ साइंसेज प्राइवेट लिमिटेड

उपभोग प्रकार :

आंत्रेतर

वापसी नीति :

वापसी योग्य नहीं

Azafect Injection 100 ml के बारे में

Azafect Injection 100 ml एंटी-मेटाबोलाइट्स नामक दवाओं के समूह से संबंधित है, जिसका उपयोग उच्च जोखिम वाले मायेलोडिस्प्लास्टिक सिंड्रोम, क्रोनिक मायलोमोनोसाइटिक ल्यूकेमिया और तीव्र मायलोइड ल्यूकेमिया वाले वयस्कों में किया जाता है। ये स्थितियाँ अस्थि मज्जा को प्रभावित करती हैं और सामान्य रक्त कोशिका उत्पादन में समस्याएँ पैदा कर सकती हैं। 
 
Azafect Injection 100 ml में एज़ासिटिडाइन होता है, जो कैंसर कोशिकाओं को बढ़ने से रोककर काम करता है। यह अस्थि मज्जा को सामान्य रक्त कोशिकाओं के उत्पादन में मदद करता है और अस्थि मज्जा में असामान्य कोशिकाओं को मारता है।
 
कुछ मामलों में, Azafect Injection 100 ml मतली, उल्टी, दस्त, कब्ज, कमजोरी, सिरदर्द और इंजेक्शन साइट प्रतिक्रियाओं जैसे दुष्प्रभावों का कारण बन सकता है। इनमें से अधिकांश दुष्प्रभावों के लिए चिकित्सा ध्यान देने की आवश्यकता नहीं हो सकती है और समय के साथ धीरे-धीरे ठीक हो सकते हैं। यदि कोई भी दुष्प्रभाव बना रहता है या बिगड़ जाता है, तो अपने डॉक्टर से बात करने में संकोच न करें।
 
यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो Azafect Injection 100 ml का उपयोग न करें। यदि आप Azafect Injection 100 ml से उपचार के दौरान गर्भवती हो जाती हैं, तो तुरंत डॉक्टर से परामर्श करें। यह दवा बच्चों के लिए अनुशंसित नहीं है क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई है। किसी भी दुष्प्रभाव/अंतःक्रिया से बचने के लिए अपने डॉक्टर को अपनी स्वास्थ्य स्थिति और दवाओं के बारे में बताएं।

Azafect Injection 100 ml का उपयोग

मायेलोडाइस्प्लास्टिक सिंड्रोम, क्रोनिक मायेलोमोनोसाइटिक ल्यूकेमिया और तीव्र मायलोइड ल्यूकेमिया का उपचार

इस्तेमाल केलिए निर्देश

Azafect Injection 100 ml एक योग्य चिकित्सक द्वारा प्रशासित किया जाएगा; स्वयं प्रशासित न करें।

औषधीय लाभ

Azafect Injection 100 ml एंटी-मेटाबोलाइट्स नामक दवाओं के समूह से संबंधित है जिसका उपयोग मायलोडिस्प्लास्टिक सिंड्रोम, क्रोनिक मायलोमोनोसाइटिक ल्यूकेमिया और एक्यूट मायलोइड ल्यूकेमिया के इलाज के लिए किया जाता है। Azafect Injection 100 ml में एज़ासिटिडाइन होता है, जो एक न्यूक्लियोसाइड मेटाबोलिक अवरोधक है जो कैंसर कोशिकाओं को बढ़ने से रोककर काम करता है। यह कोशिकाओं की आनुवंशिक सामग्री में शामिल हो जाता है और नए डीएनए और आरएनए के उत्पादन में हस्तक्षेप करता है। यह अस्थि मज्जा में युवा रक्त कोशिकाओं की परिपक्वता और वृद्धि के साथ समस्याओं को ठीक करने में मदद करता है, जो मायलोडिस्प्लास्टिक विकारों का कारण बनता है।

भंडारण

धूप से दूर ठंडी और सूखी जगह पर रखें
Side effects of Azafect Injection 100 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

दवा चेतावनियाँ

यदि आपको इसके किसी घटक से एलर्जी है, आपको उन्नत लिवर कैंसर है, या आप स्तनपान करा रही हैं, तो Azafect Injection 100 ml का उपयोग न करें। यदि आपको प्लेटलेट्स, लाल या सफेद रक्त कोशिकाओं की संख्या कम है, हृदय की स्थिति या दिल का दौरा, फेफड़े, गुर्दे या यकृत रोग हैं, तो डॉक्टर को सूचित करें। यदि आपको लिवर फेलियर (पीलिया, पेट में सूजन, कंपकंपी, उनींदापन और आसानी से चोट लगना), किडनी फेलियर (पीठ दर्द, प्यास में वृद्धि, पैरों और पैरों में सूजन, पेशाब कम होना, चक्कर आना, नाड़ी का तेज़ होना, मतली, उल्टी, भूख कम लगना, भ्रम, थकान या बेचैनी), बुखार, निमोनिया (बुखार के साथ सांस लेने में तकलीफ या सीने में दर्द), प्लेटलेट्स का कम स्तर (पेट में रक्तस्राव के कारण मल में खून आना), या एलर्जिक प्रतिक्रिया (चकत्ते, सांस लेने में कठिनाई, खुजली या होठों की सूजन) के लक्षण दिखाई देते हैं, तो तुरंत चिकित्सा सहायता लें।

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
How does the drug interact with Azafect Injection 100 ml:
Taking Yellow fever vaccine with Azafect Injection 100 ml can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Azafect Injection 100 ml and the Yellow fever vaccine, you can take these medicines together if prescribed by a doctor. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
How does the drug interact with Azafect Injection 100 ml:
Taking Azafect Injection 100 ml with Deferiprone can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Azafect Injection 100 ml with Deferiprone can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without talking to a doctor.
AzacitidineBCG vaccine
Severe
How does the drug interact with Azafect Injection 100 ml:
Taking BCG vaccine with Azafect Injection 100 ml can increase the risk of infection.

How to manage the interaction:
Co-administration of Azafect Injection 100 ml with BCG vaccine can result in an interaction, but it can be taken if a doctor has advised it. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
How does the drug interact with Azafect Injection 100 ml:
The use of cladribine with Azafect Injection 100 ml can increase the risk of infections.

How to manage the interaction:
Taking Azafect Injection 100 ml with Cladribine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience a fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Azafect Injection 100 ml:
Taking Adalimumab with Azafect Injection 100 ml may raise the risk of severe infections.

How to manage the interaction:
Taking Azafect Injection 100 ml with Adalimumab together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azafect Injection 100 ml:
Taking Infliximab with Azafect Injection 100 ml can increase the risk or severity of developing infection.

How to manage the interaction:
Although taking Azafect Injection 100 ml and Infliximab together can cause an interaction, it can be taken if a doctor has suggested it. If you experience symptoms like fever, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, and pain or burning during urination, it is recommended to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azafect Injection 100 ml:
Taking Azafect Injection 100 ml with tofacitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Azafect Injection 100 ml and Tofacitinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azafect Injection 100 ml:
Taking Azafect Injection 100 ml with Natalizumab can raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Azafect Injection 100 ml and Natalizumab, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm(a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, progressive weakness on one side of the body, clumsiness of limbs, disturbance of vision, confusion, or changes in thinking, memory and personality, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azafect Injection 100 ml:
Taking Azafect Injection 100 ml and leflunomide together may increase the chances of developing severe infections.

How to manage the interaction:
Although there is an interaction between leflunomide and Azafect Injection 100 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azafect Injection 100 ml:
Taking thalidomide together with Azafect Injection 100 ml may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Azafect Injection 100 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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  • धूम्रपान और शराब के सेवन से बचें।
  • अपने आहार में सब्जियां और फल शामिल करें।
  • फास्ट फूड, तला हुआ भोजन, प्रोसेस्ड मीट, रिफाइंड कार्बोहाइड्रेट और अतिरिक्त चीनी से बचें।
  • इष्टतम नींद लें; अच्छी तरह आराम करें।
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आदत बनाना

नहीं
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शराब

Consult your doctor

यह ज्ञात नहीं है कि शराब Azafect Injection 100 ml को प्रभावित करती है या नहीं। कृपया अपने डॉक्टर से परामर्श करें।

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गर्भावस्था

Unsafe

एज़ैसिटिडाइन गर्भावस्था श्रेणी डी से संबंधित है। Azafect Injection 100 ml का उपयोग गर्भावस्था के दौरान नहीं किया जाना चाहिए क्योंकि यह बच्चे को नुकसान पहुंचा सकता है। यदि आप Azafect Injection 100 ml के साथ उपचार के दौरान गर्भवती हो जाती हैं, तो तुरंत डॉक्टर से परामर्श करें।

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स्तनपान

Unsafe

यह अज्ञात है कि एज़ासिटिडाइन स्तन के दूध में जाता है या नहीं। Azafect Injection 100 ml के साथ उपचार के दौरान स्तनपान की अनुशंसा नहीं की जाती है।

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ड्राइविंग

Caution

Azafect Injection 100 ml चक्कर आना और थकान का कारण बन सकता है। यदि आपको कोई साइड इफ़ेक्ट महसूस होता है जिससे आपकी ऐसा करने की क्षमता कम हो सकती है, तो गाड़ी चलाने या मशीनरी चलाने से बचें।

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जिगर

Caution

यदि आपको लीवर की बीमारी का इतिहास है, तो Azafect Injection 100 ml लेने से पहले अपने डॉक्टर को सूचित करें। इस दवा का उपयोग गंभीर रूप से पहले से मौजूद लीवर की कमी वाले रोगियों में सावधानी के साथ किया जाना चाहिए।

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किडनी

Caution

यदि आपको किडनी की बीमारी का इतिहास है, तो Azafect Injection 100 ml लेने से पहले अपने डॉक्टर को सूचित करें। किडनी की खराबी वाले रोगियों की निगरानी करने की सलाह दी जाती है।

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बच्चे

Unsafe

Azafect Injection 100 ml की सिफारिश 18 वर्ष से कम उम्र के बच्चों के लिए नहीं की जाती है क्योंकि इसकी सुरक्षा और प्रभावशीलता स्थापित नहीं की गई है।

Have a query?

FAQs

Azafect Injection 100 ml कैंसर कोशिकाओं को बढ़ने से रोककर काम करता है। इस प्रकार, यह कैंसर के इलाज में मदद करता है।

पुरुषों को Azafect Injection 100 ml के साथ उपचार के दौरान बच्चे पैदा करने से बचना चाहिए। यदि आप उपचार शुरू करने से पहले अपने शुक्राणु को संरक्षित करना चाहते हैं तो डॉक्टर से परामर्श करें। Azafect Injection 100 ml के साथ उपचार के दौरान और उपचार बंद करने के तीन महीने बाद तक प्रभावी गर्भनिरोधक का उपयोग करें।

Azafect Injection 100 ml एक गंभीर प्रतिरक्षा प्रतिक्रिया का कारण बन सकता है जिसे भेदभाव सिंड्रोम के रूप में जाना जाता है। यदि आपको बुखार, दाने, सांस लेने में कठिनाई, खांसी, पेशाब में कमी, तेजी से वजन बढ़ना, निम्न रक्तचाप या पैरों या बाहों में सूजन का अनुभव होता है, तो तुरंत डॉक्टर से परामर्श करें।

उद्गम देश

भारत
Other Info - AZA0141

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