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Barinat 4 Tablet belongs to the class of immunomodulators used in the treatment of rheumatoid arthritis, atopic dermatitis and coronavirus infection. This medicine works by stopping the viral entry into body cells, limits viral replication, and thereby controls the release of cytokines. Common side effects include throat infection, fatigue and high blood cholesterol.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Barinat 4 Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • To improve liver health and aid in the removal of toxins, drink lots of water.
  • Alcohol consumption should be reduced or stopped because it can raise ALT levels and impair liver function.
  • Consume a well-rounded diet full of whole grains, fruits, and vegetables. Limit items that strain the liver, such as processed, fatty, or fried foods.
  • You can monitor your ALT levels and make treatment modifications with the support of routine blood tests.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
  • If you experience symptoms like difficulty breathing, stridor (high-pitched whistling sound when breathing), high fever or chest pain, consult a doctor immediately.
  • Use a nebulizer or a cool-mist humidifier to help loosen mucus and soothe inflamed airway.
  • Drink lots of water to thin mucus and help with coughing.
  • Get enough sleep to allow the body to heal.
  • Suck on lozenges to soothe sore throat.
  • Quit smoking and alcohol consumption.

Drug-Drug Interactions

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BaricitinibAlemtuzumab
Severe

Drug-Drug Interactions

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How does the drug interact with Barinat 4 Tablet:
Co-administration of Barinat 4 Tablet with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Ciclosporin with Barinat 4 Tablet is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
BaricitinibAlemtuzumab
Severe
How does the drug interact with Barinat 4 Tablet:
Combining Alemtuzumab with Barinat 4 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Barinat 4 Tablet with Alemtuzumab can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
BaricitinibAntithymocyte Globulin
Severe
How does the drug interact with Barinat 4 Tablet:
Taking Antithymocyte Globulin with Barinat 4 Tablet can increase the risk of developing serious infections as well as some cancers over time.

How to manage the interaction:
Taking Antithymocyte Globulin with Barinat 4 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Barinat 4 Tablet:
Coadministration of Vedolizumab with Barinat 4 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Barinat 4 Tablet and Vedolizumab, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.
How does the drug interact with Barinat 4 Tablet:
Coadministration of Clofarabine with Barinat 4 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Taking Barinat 4 Tablet with Clofarabine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Barinat 4 Tablet:
Coadministration of Barinat 4 Tablet and Busulfan can increase the risk of developing infections.

How to manage the interaction:
Although Barinat 4 Tablet with Busulfan can lead to an interaction, it can be taken if advised by the doctor. However, if you experience fever, sore throat, shortness of breath, body sores, or burning on urination, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Barinat 4 Tablet:
Coadministration of Abemaciclib with Barinat 4 Tablet can lead to or increase the risk of developing serious infections.

How to manage the interaction:
Taking Abemaciclib with Barinat 4 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in phlegm, red or inflamed skin, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Barinat 4 Tablet:
Coadministration of Idarubicin and Barinat 4 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Idarubicin can be taken with Barinat 4 Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Barinat 4 Tablet:
Taking Dimethyl fumarate with Barinat 4 Tablet may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Dimethyl fumarate can be taken with Barinat 4 Tablet if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of infection like muscle aches, shortness of breath, blood in phlegm, fever, chills, diarrhea, sore throat, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Barinat 4 Tablet:
Using deferiprone with Barinat 4 Tablet causes a reduction of white blood cell count, which may increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Barinat 4 Tablet can be taken with deferiprone if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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BARICITINIB-4MGHigh fat foods
Mild

Drug-Food Interactions

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BARICITINIB-4MGHigh fat foods
Mild
Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Coadministration of Barinat 4 Tablet and high-fat meals can decrease the absorption of Barinat 4 Tablet. Avoid fatty food and oily food while being treated with Barinat 4 Tablet.

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