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compositionComposition:AMLODIPINE-5MG+BISOPROLOL-2.5MG
prescriptionPrescription Medicine
Bisosafe AM 2.5 Tablet 10's

Bisosafe AM 2.5 Tablet 10's is used to treat high blood pressure. It contains Amlodipine and Bisoprolol, which act by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps in reducing the risk of having a stroke, heart attack, other heart problems, or kidney problems in the future. It may cause common side effects, such as headaches, fatigue, and swollen ankles. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMLODIPINE-5MG+BISOPROLOL-2.5MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Bisosafe AM 2.5 Tablet 10's

Bisosafe AM 2.5 Tablet 10's is used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications.

Bisosafe AM 2.5 Tablet 10's contains Amlodipine and Bisoprolol. Amlodipine reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol helps relax our blood vessels by blocking the action of certain natural substances in our bodies.

You may have common side effects like headaches, feeling exhausted, and swollen ankles, which usually resolve after some time. It is advised to continue taking this drug and not stop taking it suddenly without consulting your doctor.

It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Please inform your doctor if you have had an allergic reaction to Bisosafe AM 2.5 Tablet 10's, are pregnant or planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, diabetes, a heart valve problem or a heart attack.

Uses of Bisosafe AM 2.5 Tablet 10's

Bisosafe AM 2.5 Tablet 10's is used in the treatment of High blood pressure (hypertension). The detailed uses of Bisosafe AM 2.5 Tablet 10's are as follows:

  • Hypertension Treatment: Bisosafe AM 2.5 Tablet 10's is used to treat high blood pressure by relaxing blood vessels and reducing heart rate.
  • Cardiovascular Protection: Bisosafe AM 2.5 Tablet 10's helps to prevent strokes and heart attacks, reduces the risk of heart failure, and lowers cardiovascular complications.

Have a query?

Directions for Use

  • Bisosafe AM 2.5 Tablet 10's can be taken with or without food, but taking it with food may help reduce stomach upset.
  • It is usually taken once daily, preferably in the morning, or as prescribed by your doctor.
  • Swallow Bisosafe AM 2.5 Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

  • Bisosafe AM 2.5 Tablet 10's is a combination of two medicines: Amlodipine and Bisoprolol, which together help in lowering raised blood pressure effectively.
  • Amlodipine is a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. 
  • Bisoprolol (beta blocker) helps relax our blood vessels by blocking the action of certain natural substances in the body.
  • This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.
  • This medication must be taken regularly to be effective.

How Bisosafe AM 2.5 Tablet 10's Works

Bisosafe AM 2.5 Tablet 10's contains Amlodipine (calcium channel blocker) and Bisoprolol (beta blocker). Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol helps relax our blood vessels by blocking the action of certain natural substances in our bodies. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medication must be taken regularly to be effective.

Storage

Store in a cool and dry place away from sunlight
Side effects of Bisosafe AM 2.5 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Bisosafe AM 2.5 Tablet 10's

Do not take more than the prescribed dose of Bisosafe AM 2.5 Tablet 10's as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Don't stop taking Bisosafe AM 2.5 Tablet 10's without talking to your doctor first.
  • Stopping Bisosafe AM 2.5 Tablet 10's abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack.
  • Your doctor will lower your dose gradually over a period of time to help prevent these symptoms.
  • You should not use Bisosafe AM 2.5 Tablet 10's if you have a very slow heartbeat, asthma, a serious heart condition (sick sinus syndrome), or any heart blockage.
  • It should not be given to children under 12 years of age.
  • Before taking Bisosafe AM 2.5 Tablet 10's you should tell your doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problems (COPD, bronchitis, emphysema), low blood sugar level (hypoglycaemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome).

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineRifampicin
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Bisosafe AM 2.5 Tablet:
Using Bisosafe AM 2.5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Bisosafe AM 2.5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineRifampicin
Severe
How does the drug interact with Bisosafe AM 2.5 Tablet:
Coadministration of Bisosafe AM 2.5 Tablet and rifampicin together may lower Bisosafe AM 2.5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Bisosafe AM 2.5 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Bisosafe AM 2.5 Tablet:
Coadministration of Bisosafe AM 2.5 Tablet with itraconazole may significantly raise the blood levels and effects of Bisosafe AM 2.5 Tablet.

How to manage the interaction:
Bisosafe AM 2.5 Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineRifabutin
Severe
How does the drug interact with Bisosafe AM 2.5 Tablet:
Using Bisosafe AM 2.5 Tablet and rifabutin together may lower Bisosafe AM 2.5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Bisosafe AM 2.5 Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
AmlodipinePhenytoin
Severe
How does the drug interact with Bisosafe AM 2.5 Tablet:
Using Bisosafe AM 2.5 Tablet and phenytoin together may drastically lower Bisosafe AM 2.5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Bisosafe AM 2.5 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Bisosafe AM 2.5 Tablet:
Using Bisosafe AM 2.5 Tablet and primidone together may lower Bisosafe AM 2.5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Bisosafe AM 2.5 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePhenobarbital
Severe
How does the drug interact with Bisosafe AM 2.5 Tablet:
Using phenobarbital and Bisosafe AM 2.5 Tablet may drastically lower Bisosafe AM 2.5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Bisosafe AM 2.5 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineCeritinib
Severe
How does the drug interact with Bisosafe AM 2.5 Tablet:
Coadministration of Ceritinib together with Bisosafe AM 2.5 Tablet can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Bisosafe AM 2.5 Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Bisosafe AM 2.5 Tablet:
Coadministration of Bisosafe AM 2.5 Tablet and Rifapentine may significantly reduce the blood levels of Bisosafe AM 2.5 Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Bisosafe AM 2.5 Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Bisosafe AM 2.5 Tablet:
Using a combination of Bisosafe AM 2.5 Tablet and enzalutamide may drastically lower Bisosafe AM 2.5 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Bisosafe AM 2.5 Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+BISOPROLOL-2.5MGFruit juices, Fruits
Mild

Drug-Food Interactions

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AMLODIPINE-5MG+BISOPROLOL-2.5MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grapefruit or grapefruit juice with Bisosafe AM 2.5 Tablet can increase the blood levels of amlodipine. Avoid or limit consumption of grapefruit juice.

Diet & Lifestyle Advise

  • Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
  • Regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week, can help lower your raised blood pressure by about 5 mmHg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily, and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. Low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil can help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Bisosafe AM 2.5 Tablet 10's to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Bisosafe AM 2.5 Tablet 10's should not be taken until prescribed. Bisosafe AM 2.5 Tablet 10's can have some harmful effects on the baby (foetus), Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Consult your doctor

Bisosafe AM 2.5 Tablet 10's is usually not recommended in breastfeeding mothers. Limited human data available suggests that the drug does not do any significant harm to the baby. Consume only if benefits outweigh risks.

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Driving

Unsafe

It is not recommended to drive after taking Bisosafe AM 2.5 Tablet 10's as it may occasionally cause drowsiness or fatigue.

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Liver

Caution

Bisosafe AM 2.5 Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Bisosafe AM 2.5 Tablet 10's to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Bisosafe AM 2.5 Tablet 10's is not recommended in children. The safety and efficacy of Bisosafe AM 2.5 Tablet 10's in children have not yet been established.

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Heart

Caution

Bisosafe AM 2.5 Tablet 10's is often prescribed to patients with heart problems to treat hypertension. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.

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Geriatrics

Caution

Bisosafe AM 2.5 Tablet 10's should be administered with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Bisosafe AM 2.5 Tablet 10's.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 INDIA
Other Info - BIS0430

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