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Cardivas IN 12.5/5 mg Tablet is an antihypertensive medicine used to treat hypertension (high blood pressure). It is also effective in treating moderate to severe heart failure and angina (heart-related chest pain), thereby reducing the risk of heart attack or stroke in adults. It contains Carvedilol and Ivabradine. Carvedilol acts by relaxing blood vessels by blocking the action of certain natural substances like epinephrine or adrenaline. Ivabradine works by reducing the heart rate by a few beats per minute.  In this way, it lowers the heart's oxygen requirement, especially when an angina attack can happen. Thus, it lowers the raised blood pressure and keeps the heartbeat slowly and with less force, reducing the risk of having a stroke, a heart attack, or other heart problems.
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Cardivas IN 12.5 mg/5 mg Tablet:
Coadministration of Cardivas IN 12.5 mg/5 mg Tablet with Imatinib can increase the levels of Cardivas IN 12.5 mg/5 mg Tablet in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Cardivas IN 12.5 mg/5 mg Tablet with Bosutinib together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cardivas IN 12.5 mg/5 mg Tablet:
Using Cardivas IN 12.5 mg/5 mg Tablet together with posaconazole may significantly increase the blood levels and effects of Cardivas IN 12.5 mg/5 mg Tablet.

How to manage the interaction:
Taking Cardivas IN 12.5 mg/5 mg Tablet with Posaconazole together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cardivas IN 12.5 mg/5 mg Tablet:
Coadministration of Cardivas IN 12.5 mg/5 mg Tablet with Ketoconazole can increase the risk or severity of side effects.

How to manage the interaction:
Taking Cardivas IN 12.5 mg/5 mg Tablet with Ketoconazole is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cardivas IN 12.5 mg/5 mg Tablet:
Coadministration of Cardivas IN 12.5 mg/5 mg Tablet with ceritinib can increase the levels and effects of Cardivas IN 12.5 mg/5 mg Tablet.

How to manage the interaction:
Taking Cardivas IN 12.5 mg/5 mg Tablet with Ceritinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cardivas IN 12.5 mg/5 mg Tablet:
Using Cardivas IN 12.5 mg/5 mg Tablet together with voriconazole may significantly increase the blood levels and effects of Cardivas IN 12.5 mg/5 mg Tablet.

How to manage the interaction:
Taking Cardivas IN 12.5 mg/5 mg Tablet with Voriconazole together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cardivas IN 12.5 mg/5 mg Tablet:
Coadministration of thioridazine with Cardivas IN 12.5 mg/5 mg Tablet can increase the risk of low blood pressure especially when standing up.

How to manage the interaction:
Taking Thioridazine with Cardivas IN 12.5 mg/5 mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any excessive sweating, palpitations, chest discomfort, or shortness of breath. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Cardivas IN 12.5 mg/5 mg Tablet:
Co-administration of Cardivas IN 12.5 mg/5 mg Tablet with clofazimine can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Taking Cardivas IN 12.5 mg/5 mg Tablet with Clofazimine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
IvabradineEnzalutamide
Severe
How does the drug interact with Cardivas IN 12.5 mg/5 mg Tablet:
Taking Enzalutamide with Cardivas IN 12.5 mg/5 mg Tablet may decrease the blood levels of Cardivas IN 12.5 mg/5 mg Tablet, which may make Cardivas IN 12.5 mg/5 mg Tablet less effective in treating your condition.

How to manage the interaction:
Although taking Enzalutamide and Cardivas IN 12.5 mg/5 mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Cardivas IN 12.5 mg/5 mg Tablet:
Coadministration of Cardivas IN 12.5 mg/5 mg Tablet with Mirtazapine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Cardivas IN 12.5 mg/5 mg Tablet with Mirtazapine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cardivas IN 12.5 mg/5 mg Tablet:
Coadministration of Cardivas IN 12.5 mg/5 mg Tablet with Darunavir can reduce the metabolism and increase the levels of Cardivas IN 12.5 mg/5 mg Tablet in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Cardivas IN 12.5 mg/5 mg Tablet with Darunavir together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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