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Carloc I 6.25 Tablet is an antihypertensive medicine used to treat hypertension (high blood pressure). It is also effective in treating moderate to severe heart failure and angina (heart-related chest pain), thereby reducing the risk of heart attack or stroke in adults. It contains Carvedilol and Ivabradine. Carvedilol acts by relaxing blood vessels by blocking the action of certain natural substances like epinephrine or adrenaline. Ivabradine works by reducing the heart rate by a few beats per minute.  In this way, it lowers the heart's oxygen requirement, especially when an angina attack can happen. Thus, it lowers the raised blood pressure and keeps the heartbeat slowly and with less force, reducing the risk of having a stroke, a heart attack, or other heart problems.
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Carloc I 6.25 Tablet:
Coadministration of Carloc I 6.25 Tablet with ceritinib can increase the levels and effects of Carloc I 6.25 Tablet.

How to manage the interaction:
Taking Carloc I 6.25 Tablet with Ceritinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Carloc I 6.25 Tablet:
Coadministration of Carloc I 6.25 Tablet with Imatinib can increase the levels of Carloc I 6.25 Tablet in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Carloc I 6.25 Tablet with Bosutinib together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Carloc I 6.25 Tablet:
Using Carloc I 6.25 Tablet together with voriconazole may significantly increase the blood levels and effects of Carloc I 6.25 Tablet.

How to manage the interaction:
Taking Carloc I 6.25 Tablet with Voriconazole together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Carloc I 6.25 Tablet:
Using Carloc I 6.25 Tablet together with posaconazole may significantly increase the blood levels and effects of Carloc I 6.25 Tablet.

How to manage the interaction:
Taking Carloc I 6.25 Tablet with Posaconazole together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Carloc I 6.25 Tablet:
Coadministration of Carloc I 6.25 Tablet with Ketoconazole can increase the risk or severity of side effects.

How to manage the interaction:
Taking Carloc I 6.25 Tablet with Ketoconazole is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Carloc I 6.25 Tablet:
Coadministration of thioridazine with Carloc I 6.25 Tablet can increase the risk of low blood pressure especially when standing up.

How to manage the interaction:
Taking Thioridazine with Carloc I 6.25 Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any excessive sweating, palpitations, chest discomfort, or shortness of breath. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Carloc I 6.25 Tablet:
Coadministration of Carloc I 6.25 Tablet with clotrimazole may increase the blood levels of Carloc I 6.25 Tablet, which may result in an excessive slowing of the heart rate.

How to manage the interaction:
Although taking Clotrimazole with Carloc I 6.25 Tablet may result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience dizziness, fatigue, or low blood pressure. irregular heartbeat, or shortness of breath, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Carloc I 6.25 Tablet:
Coadministration of Carloc I 6.25 Tablet with Promethazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Carloc I 6.25 Tablet with Promethazine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Carloc I 6.25 Tablet:
Coadministration of Carloc I 6.25 Tablet with Sorafenib can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Carloc I 6.25 Tablet with Sorafenib together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IvabradineFosphenytoin
Severe
How does the drug interact with Carloc I 6.25 Tablet:
Coadministration of Carloc I 6.25 Tablet with Fosphenytoin can induce the metabolism and decrease the levels of Carloc I 6.25 Tablet in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Carloc I 6.25 Tablet with Fosphenytoin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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