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Coflam MR 400mg/325mg/250mg Tablet
Coflam MR 400mg/325mg/250mg Tablet is used in the reduction of musculoskeletal pain and muscle spasm due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid). It works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Also, it helps by blocking nerve impulses or pain sensations sent by the brain and causes the relaxation of muscles. It may cause side effects such as nausea, indigestion, diarrhoea, drowsiness, dizziness, heartburn, stomach pain and restlessness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Coflam MR 400mg/325mg/250mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Eosinophil levels can be lowered by eating fruits and vegetables, avoiding smoking, and consuming alcohol in moderation.
  • Several foods, such as ginger, garlic, pepper, turmeric, and honey, might boost immunity.
  • Avoid dairy products, including cheese, yoghurt, and milk.
  • Drink water and keep yourself hydrated.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Low levels of protein in the blood could be due to underlying kidney or liver disease, malnutrition or any medication.
  • Intake of healthy and nutritious food that can enhance your blood protein level can be helpful.
  • Regularly practising yoga or meditation can improve your health and absorption of nutrients.
  • Avoid hair loss by taking protein that can improve hair growth.
  • Establish a consistent sleep schedule.
  • Limit or avoid alcohol and recreational substances.

Have a query?

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Coflam MR 400mg/325mg/250mg Tablet is shown to interact with various drugs. Some of them include pain killers (naproxen, aspirin, ibuprofen, tramadol, hydrocodone, oxycodone), lithium, anticancer/antimetabolites (methotrexate), blood thinner or anticoagulant (warfarin, coumadin, jantoven), blood pressure or heart medicine, nausea medicine (metoclopramide, domperidone), diuretic/water pills (thiazides, furosemide), a steroid medicine (prednisone), quinolones antibiotics (ciprofloxacin), respiratory medicines (theophyllines, ephedrine), cholesterol-reducing medicine (colestyramine) and antidepressants (duloxetine). These drugs may affect the working of Coflam MR 400mg/325mg/250mg Tablet and may alter its efficacy.

Drug-Food Interaction: Excessive intake of caffeine-containing food or drinks like coffee, tea, chocolate and some fizzy drinks should be avoided while taking Coflam MR 400mg/325mg/250mg Tablet. Taking them together may lead to drowsiness and dizziness and sleepiness. And also, consuming alcohol along with Coflam MR 400mg/325mg/250mg Tablet can cause excessive ingestion of alcohol and potentiate liver damage action of paracetamol. 

Drug-Disease Interaction: Coflam MR 400mg/325mg/250mg Tablet should not recommend for people having bleeding disorders, like haemophilia, von Willebrand disease or low blood platelets. Besides this, it should not be given to children suffering from influenza (flu) or chickenpox. It should also be avoided in case of the presence of gastric or duodenal ulcers.

Ibuprofen + Paracetamol + ChlorzoxazoneKetorolac
Critical
Ibuprofen + Paracetamol + ChlorzoxazoneMeloxicam
Critical

Drug-Drug Interactions

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Ibuprofen + Paracetamol + ChlorzoxazoneKetorolac
Critical
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Combining Coflam MR 400mg/325mg/250mg Tablet with ketorolac can increase the risk of such as inflammation(redness and swelling) bleeding and ulceration in the stomach.

How to manage the interaction:
Taking Coflam MR 400mg/325mg/250mg Tablet together with ketorolac is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Ibuprofen + Paracetamol + ChlorzoxazoneMeloxicam
Critical
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Combining Coflam MR 400mg/325mg/250mg Tablet and Meloxicam can increase the risk of such as inflammation(redness and swelling) bleeding and ulceration in the stomach.

How to manage the interaction:
Taking Coflam MR 400mg/325mg/250mg Tablet together with Meloxicam is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

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