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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Colchimap Tablet 10's is used to prevent and treat gout attacks and relieve the pain of gout attacks. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, and cardiovascular death. It works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever. This medicine may cause side effects such as diarrhoea, nausea, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Side effects of Colchimap Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink plenty of fluids and stay hydrated.
  • Avoid foods containing sugars, salts and processed food.
  • Avoid consumption of alcohol.
  • Take healthy diet containing fiber, carbohydrates and lean proteins.
  • Exercise regularly and maintain a healthy lifestyle.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Colchimap Tablet:
Coadministration of Colchimap Tablet with clarithromycin may increase the blood levels of Colchimap Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchimap Tablet with Clarithromycin is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Colchimap Tablet:
Using Colchimap Tablet together with ketoconazole may increase the blood levels of Colchimap Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Ketoconazole with Colchimap Tablet is not recommended as it can cause an interaction, they can be taken if prescribed by a doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without consulting a doctor
How does the drug interact with Colchimap Tablet:
Coadministration of Colchimap Tablet with darunavir may increase the blood levels of Colchimap Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchimap Tablet with Darunavir is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Colchimap Tablet:
Coadministration of Colchimap Tablet with itraconazole may increase the blood levels of Colchimap Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Colchimap Tablet with itraconazole can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Colchimap Tablet:
Coadministration of Colchimap Tablet and propafenone may increase the blood levels of Colchimap Tablet, increasing the risk of side effects.

How to manage the interaction:
Although taking Colchimap Tablet and Propafenone together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Colchimap Tablet:
Coadministration of amiodarone with Colchimap Tablet may increase the Colchimap Tablet levels, leading to an increased risk or severity of side effects.

How to manage the interaction:
Taking amiodarone and Colchimap Tablet together can lead to an interaction, but they can be taken together if your doctor has advised it. However, consult a doctor if you experience abdominal discomfort, diarrhoea, fever, muscle pain, tiredness, weakness, and numbness or tingling in your hands and feet. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Colchimap Tablet:
Co-administration of Aprepitant with Colchimap Tablet may raise blood levels of Colchimap Tablet, which can have an effect on the neurological system and other organs such as the liver and kidneys.

How to manage the interaction:
Although taking Aprepitant with Colchimap Tablet may cause an interaction, it is safe to do so if advised by your doctor. Consult a doctor if you have abdominal discomfort, nausea, vomiting, diarrhea, fever, muscle pain, fatigue, weakness, or numbness or tingling in your hands or feet. Do not discontinue any medications without consulting a doctor.
ColchicineVenetoclax
Severe
How does the drug interact with Colchimap Tablet:
When Colchimap Tablet is taken with Venetoclax, the amount of Colchimap Tablet in the blood can go up.

How to manage the interaction:
Co-administration of Colchimap Tablet with Venetoclax can result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience Stomach pain, diarrhea, nausea, and vomiting. Do not stop using any medications without a doctor's advice.
How does the drug interact with Colchimap Tablet:
Coadministration of Colchimap Tablet and Tacrolimus increases Colchimap Tablet levels in the blood.

How to manage the interaction:
Although taking Colchimap Tablet and Tacrolimus together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, if you experience any symptoms like nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Colchimap Tablet:
Coadministration of Colchimap Tablet with daclatasvir may increase the blood levels of Colchimap Tablet, increasing the risk of side effects.

How to manage the interaction:
Although taking Colchimap Tablet and Daclatasvir together may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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COLCHICINE-0.5MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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COLCHICINE-0.5MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming excessive quantities of grapefruit juice can raise the levels of Colchimap Tablet in your blood, increasing the risk of side effects. Avoid the consumption of grapefruit juice while taking Colchimap Tablet.

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