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compositionComposition:HYDROXYUREA-500MG
prescriptionPrescription Medicine
Cytodrox Capsule 10's
Cytodrox Capsule 10's

Cytodrox Capsule is used to treat head and neck cancer and sickle cell anaemia (blocking the flow of blood that causes pain and organ damage). It works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) (haemoglobin of the unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, restores the flow of blood, and protects against problems like painful sickle cell attacks. It may cause side effects such as loss of appetite (feeling unwell and stomach upset), increased bleeding tendency, nausea, upset stomach, and vomiting.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

HYDROXYUREA-500MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Cytodrox Capsule

Cytodrox Capsule is an anticancer medicine used to treat head and neck cancer and sickle cell anaemia (blocking the flow of blood that causes pain and organ damage). Head and neck cancer is a disease including abnormal growth of the tissues of the neck and head that may also have the ability to attack or spread to other portions of the body.

In cancer, Cytodrox Capsule works by blocking an enzyme that is required for growing cells. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) (haemoglobin of the unborn baby) levels in red blood cells (RBCs).

You may experience loss of appetite (feeling unwell and stomach upset), increased bleeding tendency, nausea, upset stomach, and vomiting. Most of these side effects of Cytodrox Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take Cytodrox Capsule as prescribed by your doctor. You are advised to take Cytodrox Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. Do not chew, break, or crush the medicine. Swallow the medicine as a whole with a glass of water.

Before starting Cytodrox Capsule , please inform your doctor if you have any allergies, kidney disease, liver disease, injury to your legs, HIV or AIDS, high levels of uric acid in your blood, or treatment with chemotherapy or radiation. Cytodrox Capsule may increase the chances of other cancer. Inform your doctor about this risk. Immediately contact your doctor if you are pregnant because this Cytodrox Capsule can cause harmful effects on the unborn baby.

Uses of Cytodrox Capsule

Cytodrox Capsule is used in the treatment of head and neck cancer, blood cancer, and sickle cell anaemia. The detailed uses of Cytodrox Capsule are as follows:

  • Treats Head and Neck Cancer:Cytodrox Capsule is used alone or in combination with radiotherapy to treat squamous cell carcinoma (skin cancer) of the head and neck by preventing the cancer cells from growing and multiplying.
  • Treats Blood Cancer: Cytodrox Capsule helps slow the progression of chronic myeloid leukaemia by reducing the number of abnormal white blood cells in the bone marrow and blood.
  • Manages Ovarian Cancer: Cytodrox Capsule is used as part of a chemotherapy treatment to help control the growth and spread of ovarian cancer cells.
  • Manages Sickle Cell Anaemia: Cytodrox Capsule increases the level of fetal haemoglobin, which helps reduce the frequency of painful sickle cell attacks, the need for blood transfusion, and complications such as acute chest syndrome.

Health Queries

My mother has blood cancer and recently had her first induction chemotherapy. In her CBC test, immature myeloid cells are at 18 percent. What does this indicate, and is it serious?

Veda Maddala

Veda Maddala

M Pharmacy

After induction chemotherapy, some immature myeloid cells (18 percent) may still appear while the bone marrow is healing. It does not always mean the cancer is worsening, but the doctor will compare this with blast percentage in the bone marrow, which is what truly indicates remission or persistence. Regular follow-up tests are crucial.

What is T-cell all, and what treatment is needed? My mother's report shows less than 5 percent blast after 1 month of treatment.

Veda Maddala

Veda Maddala

M Pharmacy

T-cell ALL is an aggressive blood cancer where immature T-cells (blasts) grow uncontrollably. Treatment usually includes intensive chemotherapy, sometimes targeted therapy, and possibly a stem cell transplant. Having less than 5 percent blasts after 1 month is a good response, often called remission or near-remission.

The smear shows metastatic mucinous adenocarcinoma. My mom had stomach pain, and ultrasound showed a neoplasm in the stomach pylorus. Is there any treatment for this?

Veda Maddala

Veda Maddala

M Pharmacy

Yes, treatment for metastatic mucinous adenocarcinoma is possible, but it depends on the stage and spread. Options usually include chemotherapy, targeted therapy, and sometimes surgery if feasible. Her oncologist will plan treatment based on full scan and biopsy results.

My 4-year-old son has sickle cell disease. Is there a permanent cure, and how can it be achieved?

Veda Maddala

Veda Maddala

M Pharmacy

Yes, a permanent cure is possible through a bone marrow (stem cell) transplant from a matched donor. Additionally, new options for gene therapy are being developed. These options are not suitable for everyone, but they are the only treatments that can fully eliminate the disease.

My friends say my reports indicate leukemia. Can you help and suggest what medicine to take if it's not leukemia?

Veda Maddala

Veda Maddala

M Pharmacy

Only a doctor can confirm leukemia by checking your bone marrow report, blood counts, and smear. Treatment depends entirely on the confirmed diagnosis, so don't start any medicine until a specialist has reviewed it. However, you can share the exact report wording if you want help understanding it.

Have a query?

Directions for Use

  • Take Cytodrox Capsule with or without food as advised by your doctor.
  • Cytodrox Capsule is generally taken once a day or as directed by the doctor.
  • Swallow Cytodrox Capsule as a whole with a glass of water.
  • Do not chew, crush, or break it.

Key Benefits

  • Cytodrox Capsule belongs to a group of the class known as an antimetabolite.
  • It is used to treat head and neck cancer and sickle cell anaemia (blocking the flow of blood that causes pain and organ damage).
  • In cancer, Cytodrox Capsule works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing.
  • In sickle cell disease, it works by increasing fetal haemoglobin (HbF) (haemoglobin of the unborn baby) levels in red blood cells (RBCs).
  • This helps the RBCs assume a normal shape, restores blood flow, and protects against problems like painful sickle cell attacks.

How Cytodrox Capsule Works

Cytodrox Capsule works by blocking an enzyme required for cell growth. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) (haemoglobin of the unborn baby) levels in red blood cells (RBCs). This helps the RBCs assume a normal shape, restores blood flow, and protects against problems like painful sickle cell attacks.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Cytodrox Capsule

Do not take more than the prescribed dose of Cytodrox Capsule as it may cause an overdose. The symptoms of overdose include darkening of the skin, sores in the mouth and throat and pain, redness, swelling, and scaling on the hands and feet. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Before taking Cytodrox Capsule inform your doctor if you have any kind of infection because Cytodrox Capsule may worsen the infections.
  • Consult your doctor if you experience any allergy symptoms.
  • Inform your doctor if you have any history of kidney disease, liver disease, injury to your legs, HIV or AIDS, high levels of uric acid in your blood, or treatment with chemotherapy or radiation.
  • Cytodrox Capsule may increase the chances of other cancers. Inform your doctor about this risk.
  • Immediately contact your doctor if you are pregnant because this Cytodrox Capsule can cause harmful effects on the unborn baby.
  • Both women and men using this Cytodrox Capsule should use birth control to avoid pregnancy. 
  • The use of this Cytodrox Capsule by either parent may result in birth defects.
  • You should not take this Cytodrox Capsule during breastfeeding; inform your doctor if you take Cytodrox Capsule .
  • If any powder from a damaged pill is leaked, wash it up immediately with a wet paper towel and dispose of the towel in a closed plastic bag out of reach of children.

Drug-Drug Interactions

verifiedApollotooltip
HydroxycarbamideBaricitinib
Severe
HydroxycarbamideBacitracin
Severe

Drug-Drug Interactions

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HydroxycarbamideBaricitinib
Severe
How does the drug interact with Cytodrox Capsule:
Taking Baricitinib with Cytodrox Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Although Baricitinib and Cytodrox Capsule together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
HydroxycarbamideBacitracin
Severe
How does the drug interact with Cytodrox Capsule:
Cytodrox Capsule when used in conjunction with bacitracin may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Cytodrox Capsule with bacitracin, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideLeflunomide
Severe
How does the drug interact with Cytodrox Capsule:
Cytodrox Capsule when used with leflunomide may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Cytodrox Capsule with leflunomide, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideRopivacaine
Severe
How does the drug interact with Cytodrox Capsule:
Ropivacaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Cytodrox Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Cytodrox Capsule and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideLevobupivacaine
Severe
How does the drug interact with Cytodrox Capsule:
Levobupivacaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Cytodrox Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficit may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Cytodrox Capsule and levobupivacaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideBupivacaine
Severe
How does the drug interact with Cytodrox Capsule:
Taking Bupivacaine and Cytodrox Capsule may cause methemoglobinemia (a rare disorder in which the iron in the hemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately).

How to manage the interaction:
Although taking Cytodrox Capsule and bupivacaine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideInfliximab
Severe
How does the drug interact with Cytodrox Capsule:
Cytodrox Capsule when used together with infliximab may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Cytodrox Capsule with infliximab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideNatalizumab
Severe
How does the drug interact with Cytodrox Capsule:
Taking Cytodrox Capsule with natalizumab, especially taking both simultaneously, may raise the risk of serious infections, which may lead to infections like progressive multifocal leukoencephalopathy (PML), an uncommon but dangerous viral infection of the brain that can result in impairment.

How to manage the interaction:
Co-administration of Cytodrox Capsule with natalizumab can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor immediately if you are experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. If you have growing weakness on one side of your body, awkwardness of limbs, visual disruption, disorientation, or changes in thinking, memory, or personality, inform your doctor.
HydroxycarbamidePrilocaine
Severe
How does the drug interact with Cytodrox Capsule:
Prilocaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Cytodrox Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Cytodrox Capsule and Prilocaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideEtanercept
Severe
How does the drug interact with Cytodrox Capsule:
Cytodrox Capsule when used in conjunction with etanercept may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Cytodrox Capsule with etanercept, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take Cytodrox Capsule at the same time daily, either with or without a meal.
  • It is recommended to remain hydrated and drink a lot of fluids while taking Cytodrox Capsule .
  • Do not miss any dose and finish the course as recommended by your doctor.
  • Use an efficient method of birth control to prevent pregnancy while taking this Cytodrox Capsule .
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count.

Habit Forming

No

Therapeutic Class

[ANTIMETABOLITES]

All Substitutes & Brand Comparisons

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Alcohol

Consult your doctor

The drinking of alcohol (in small amounts) does not appear to affect the safety or usefulness of Cytodrox Capsule . Taking alcohol in larger amounts causes dizziness.

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Pregnancy

Unsafe

Cytodrox Capsule is not safe during pregnancy because it may cause harmful effects to the baby.

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Breast Feeding

Consult your doctor

It is unknown whether Cytodrox Capsule is excreted in human milk. Please consult a doctor before using Cytodrox Capsule while breastfeeding.

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Driving

Caution

Cytodrox Capsule may cause dizziness or a severe headache. Therefore, drive only if you are alert after taking Cytodrox Capsule .

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Liver

Consult your doctor

If you have any concerns regarding the use of Cytodrox Capsule in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Cytodrox Capsule in patients with kidney problems, please consult a doctor.

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Children

Unsafe

The safety and efficacy of Cytodrox Capsule have not been established in children. Therefore, it is not recommended for children.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Cytodrox Capsule in elderly patients. Please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - CYT0063

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