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Defstead 6 Tablet 10's
Defstead 6 Tablet 10's

Defstead 6 mg Tablet is used to treat Duchenne muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which inhibits the production of chemicals called cytokines responsible for inflammation. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Defstead 6 Tablet
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink six to eight glasses of water per day to be healthy.
  • Healthy urinary habits can help minimize pollakiuria (frequent urinating).
  • Avoid liquids containing caffeine, artificial sweeteners, and soda, as they might cause bladder discomfort.
  • Add bladder-friendly foods such as omega-3 fatty acids, blueberries, and cranberries.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Regular cleansing will help get rid of dead skin cells and stop ingrown hairs.
  • Keep your hormones in balance by managing your stress, eating well and exercising regularly.
  • Shaving, waxing, and bleaching are ways to get rid of extra hair.

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Drug-Drug Interactions

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Drug-Drug Interaction: Defstead 6 mg Tablet interacts with anti-tuberculosis (anti-TB) drugs like rifampicin and rifabutin, pain-relieving drugs like carbamazepine, Anti-seizure drugs like phenobarbital, phenytoin, and pyrimethamine, and antifungals like ketoconazole.

Drug-Food interaction: Not advised to be taken with grapefruit or its juice.

Drug-Disease interaction: Care should be exercised when Defstead 6 mg Tablet is administered in patients with diabetes, cataracts, Thyroid, blood pressure, kidney diseases, glaucoma, and herpes.

DeflazacortDesmopressin
Critical
DeflazacortFluconazole
Severe

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
How does the drug interact with Defstead 6 Tablet:
Co-administration of Defstead 6 Tablet and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
DeflazacortFluconazole
Severe
How does the drug interact with Defstead 6 Tablet:
Co-administration of Fluconazole with Defstead 6 Tablet can increase the levels of Defstead 6 Tablet in the body.

How to manage the interaction:
Taking Fluconazole with Defstead 6 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like muscle weakness, excessive growth of facial or body hair, or sudden dizziness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortAdalimumab
Severe
How does the drug interact with Defstead 6 Tablet:
Combining Adalimumab with Defstead 6 Tablet can increase the risk of severity of side effects.

How to manage the interaction:
Although there is a possibility of interaction between Defstead 6 Tablet and Adalimumab, it can be taken if prescribed by a doctor. If you have any symptoms like fever, chills, diarrhea, a sore throat, muscle pain, or experiencing pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeflazacortPrimidone
Severe
How does the drug interact with Defstead 6 Tablet:
Taking Primidone with Defstead 6 Tablet may significantly reduce the blood levels of Defstead 6 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Primidone and Defstead 6 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortRifampicin
Severe
How does the drug interact with Defstead 6 Tablet:
Taking Rifampicin with Defstead 6 Tablet may reduce the blood levels of Defstead 6 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Defstead 6 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
DeflazacortErythromycin
Severe
How does the drug interact with Defstead 6 Tablet:
Coadministration of Erythromycin with Defstead 6 Tablet can increase the levels of Defstead 6 Tablet in the body.

How to manage the interaction:
Taking Erythromycin with Defstead 6 Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms like muscle weakness, excessive growth of facial or body hair, increased body fat, sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortAmprenavir
Severe
How does the drug interact with Defstead 6 Tablet:
Coadministration of Amprenavir with Defstead 6 Tablet can increase the levels of Defstead 6 Tablet in the body.

How to manage the interaction:
Taking Amprenavir with Defstead 6 Tablet together can result in an interaction. It can be taken if your doctor has advised it. However, if you experience symptoms like muscle weakness, excessive growth of facial or body hair, sudden dizziness, lightheadedness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortVoclosporin
Severe
How does the drug interact with Defstead 6 Tablet:
Co-administration of Defstead 6 Tablet with Voclosporin may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Defstead 6 Tablet and Voclosporin, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeflazacortNelfinavir
Severe
How does the drug interact with Defstead 6 Tablet:
Coadministration of Nelfinavir with Defstead 6 Tablet can increase the levels of Defstead 6 Tablet in the body.

How to manage the interaction:
Taking Nelfinavir with Defstead 6 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like high blood pressure, high blood glucose, muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and increased body fat, sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortNefazodone
Severe
How does the drug interact with Defstead 6 Tablet:
Coadministration of Nefazodone with Defstead 6 Tablet can increase the levels of Defstead 6 Tablet in the body.

How to manage the interaction:
Taking Nefazodone with Defstead 6 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like high blood pressure, high blood glucose, muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DEFLAZACORT-6MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DEFLAZACORT-6MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit juice while on Defstead 6 Tablet therapy may elevate Defstead 6 Tablet levels in the bloodstream. Avoid or limit the consumption of grapefruit and grapefruit juice.

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