DEFLAZACORT belongs to the class of medication called steroid primarily used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy, psoriasis & arthritis, etc.
DEFLAZACORT is an immunosuppressive drug that works by binding to immune system cells and turns off the switches (receptors) that lead to their abnormal functioning or damaging effects. After taking the drug DEFLAZACORT binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a DEFLAZACORT class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. DEFLAZACORT make organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.
DEFLAZACORT is available in both oral tablet and suspension dosage forms. The tablet form of DEFLAZACORT can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of DEFLAZACORT can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take DEFLAZACORT based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremor, nervousness, diarrhoea and fast heartbeats. Most of these side effects of DEFLAZACORT do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.
Before starting DEFLAZACORT, please inform your doctor that you are allergic (hypersensitive) to DEFLAZACORT. Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors' consultation is required as DEFLAZACORT is not safe to use during pregnancy.
Duchenne muscular dystrophy (DMD)
DEFLAZACORT is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). DEFLAZACORT is a steroid that interacts with overactive immune cells and slows their activity and decreases the damaging effects they cause in the body.
Most of the side effects of DEFLAZACORT do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behaviour, fever, back pain, acne, nausea, restlessness, nosebleeds and stretch marks.
Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using DEFLAZACORT. This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using DEFLAZACORT. Before taking DEFLAZACORT for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions.
Drug-Drug interaction: DEFLAZACORT interact with anti-tuberculosis (anti TB) drugs like rifampicin, rifabutin, pain-relieving drugs like carbamazepine, Anti-seizure drugs like phenobarbitone, phenytoin & pyrimidine & antifungal like ketoconazole.
Drug-Food interaction: Not advised to be taken with grapefruit or its juice.
Drug-Disease interaction: Care should be exercised when DEFLAZACORT is administered in patients with diabetes, cataracts, Thyroidism, blood pressure, kidney diseases, glaucoma & herpes.
The effect of taking both alcohol and DEFLAZACORT may lead to bleeding & ulcers in the stomach. Doctors' consultation is recommended.
Not recommended in pregnant females.DEFLAZACORT crosses the placenta and doses equivalent to >40 mg prednisolone daily increase the risk of fetal and neonatal damage.
No adverse effect is reported yet it is advised to have doctors' consultation by breastfeeding mothers.
A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.
If you've ever had hepatitis B or if you are a carrier of hepatitis B, using DEFLAZACORT can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using DEFLAZACORT.
Before using DEFLAZACORT by a kidney patient it is recommended to have a doctors consultation. It may affect the kidney in a few cases.
DEFLAZACORT is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using DEFLAZACORT.
A patient needs to take extra care of hygiene & stay away from places/people believed to be a cause of infection as this drug affects a patient's immune system & thus proper care is to be taken.
Autoimmune disease: These are a group of disorders in which the immune system doesn't work properly due to various genetic & environmental reasons that starts attacking normal cells, producing various chemicals resulting in unwanted and hazardous effects in patients. The overactive immune system leads to various symptoms that affect day to day life and promote diseases like arthritis, muscular weakness. The immune system can also damage the organ, which has been transplanted to the patient from another person due to having different blood groups/antigens of donor patients organ. The immune system considers it a foreign harmful body, leading to complications after transplanting an organ like a kidney, liver, or heart.
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