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DEPOCILONE-40MG/1ML INJECTION is used to treat the pain of osteoarthritis (OA) in the knee. It helps to reduce the joint pain, stiffness, and swelling associated with inflammatory disorders. It contains triamcinolone acetonide, which belongs to the class of corticosteroids. It works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies. This effect helps reduce swelling, pain, and discomfort.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Depocilone 40 mg Injection 1 ml:
Co-administration of desmopressin together with Depocilone 40 mg Injection 1 ml may increase the risk of hyponatremia (a condition associated with low levels of salt in the blood).

How to manage the interaction:
Taking Depocilone 40 mg Injection 1 ml with Desmopressin is not recommended, but it should be taken if advised by a doctor. However, if you experience nausea, vomiting, headache, tiredness, irritability, difficulty concentrating, confusion, muscle spasm, weakness, , decreased urination and loss of appetite(less desire to eat), contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Using Mifepristone with Depocilone 40 mg Injection 1 ml can significantly reduce the effects of Depocilone 40 mg Injection 1 ml.

How to manage the interaction:
Taking Depocilone 40 mg Injection 1 ml with Mifepristone is not recommended but can be taken if prescribed by a doctor. However, if you notice any unusual symptoms contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Taking Depocilone 40 mg Injection 1 ml with ceritinib may increase the blood levels of Depocilone 40 mg Injection 1 ml.

How to manage the interaction:
Although there is an interaction between Depocilone 40 mg Injection 1 ml and ceritinib, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, menstrual irregularities, or excessive growth of facial or body hair. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Taking posaconazole and Depocilone 40 mg Injection 1 ml can raise the levels of Depocilone 40 mg Injection 1 ml in the blood and increase its effects.

How to manage the interaction:
Although using Posaconazole and Depocilone 40 mg Injection 1 ml together can result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience swelling, weakness, depression, easy bruising, thinning skin, menstruation abnormalities, or excessive face or body hair growth. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Taking bupropion with Depocilone 40 mg Injection 1 ml can increase the risk of seizures (fits).

How to manage the interaction:
Although there is an interaction between bupropion and Depocilone 40 mg Injection 1 ml, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Taking levofloxacin with Depocilone 40 mg Injection 1 ml may increase the risk of tendinitis(inflammation of the thick fibrous cords that attach muscle to bone)

How to manage the interaction:
Although there is an interaction between levofloxacin and Depocilone 40 mg Injection 1 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience pain, swelling, or inflammation in a tendon such as the back of the ankle, shoulder, biceps, hand, or thumb. Do not stop taking any medications without consulting your doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Taking adalimumab with Depocilone 40 mg Injection 1 ml may increase the risk of infections.

How to manage the interaction:
Although there is an interaction between Depocilone 40 mg Injection 1 ml and adalimumab, they can be taken together if prescribed by the doctor. Consult the doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
TriamcinoloneDesirudin
Severe
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Using desirudin together with Depocilone 40 mg Injection 1 ml may increase the risk of bleeding

How to manage the interaction:
Although taking Depocilone 40 mg Injection 1 ml and Desirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Co-administration of Depocilone 40 mg Injection 1 ml with atazanavir can increase the blood levels of Depocilone 40 mg Injection 1 ml.

How to manage the interaction:
Although there is an interaction between Depocilone 40 mg Injection 1 ml and atazanavir, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience swelling, weight gain, high blood glucose, muscle weakness, acne, thinning skin, stretch marks, menstrual irregularities, and excessive growth of facial or body hair. Do not any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
The use of Depocilone 40 mg Injection 1 ml together with ofloxacin may raise the risk of an abnormal heart rhythm. If you have other cardiac disorders, or electrolyte imbalances, you may be more at risk.

How to manage the interaction:
Although Ofloxacin and Depocilone 40 mg Injection 1 ml interact, they can be used if prescribed by a doctor. Consult a doctor if you have sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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