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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Deriphyllin OD 450 Tablet is a bronchodilator used to treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). It contains the active ingredients theophylline and etofylline, which help relax the muscles in the airways, improving airflow to the lungs. This action helps alleviate symptoms such as coughing, wheezing, and shortness of breath. Common side effects may include nausea, vomiting, headache, restlessness, dizziness, irregular heartbeat, and stomach upset.

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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Deriphyllin OD 450 Tablet:
Co-administration of Deriphyllin OD 450 Tablet with Riociguat can increase the risk of low blood pressure.

How to manage the interaction:
Taking Deriphyllin OD 450 Tablet with Riociguat is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, fainting, flushing (a sudden reddening of the face), headache, and nasal congestion (stuffy nose). Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin OD 450 Tablet:
Combined use of Nebivolol with Deriphyllin OD 450 Tablet may increase the effect of Deriphyllin OD 450 Tablet.

How to manage the interaction:
Although there is a possible interaction between Deriphyllin OD 450 Tablet and Nebivolol, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, irregular heartbeats, contact a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Deriphyllin OD 450 Tablet:
Taking Metoprolol Succinate with Deriphyllin OD 450 Tablet, could make Metoprolol Succinate less effective and enhance the effects of Deriphyllin OD 450 Tablet.

How to manage the interaction:
Although taking metoprolol succinate and Deriphyllin OD 450 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin OD 450 Tablet:
Co-administration of Bisoprolol with Deriphyllin OD 450 Tablet may cause Bisoprolol to be less effective and increase the effects of Deriphyllin OD 450 Tablet.

How to manage the interaction:
Although there may be an interaction, Bisoprolol can be taken with Deriphyllin OD 450 Tablet if prescribed by the doctor. Consult the prescriber if you experience nausea, vomiting, insomnia, shaking hands and legs, restlessness, uneven heartbeats, or difficulty breathing. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Deriphyllin OD 450 Tablet:
Co-administration of tramadol with Deriphyllin OD 450 Tablet can increase the effect of tramadol.

How to manage the interaction:
Taking Deriphyllin OD 450 Tablet with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllinePindolol
Severe
How does the drug interact with Deriphyllin OD 450 Tablet:
Taking pindolol with Deriphyllin OD 450 Tablet, could make pindolol less effective and increase the effects of Deriphyllin OD 450 Tablet.

How to manage the interaction:
Although taking pinolol and Deriphyllin OD 450 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin OD 450 Tablet:
Taking carvedilol with Deriphyllin OD 450 Tablet, could make carvedilol less effective and increase the effects of Deriphyllin OD 450 Tablet.

How to manage the interaction:
Although Carvedilol and Deriphyllin OD 450 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, restlessness, palpitations, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin OD 450 Tablet:
Taking Metoprolol Tartrate with Deriphyllin OD 450 Tablet could make Metoprolol Tartrate less effective and increase the side effects of Deriphyllin OD 450 Tablet

How to manage the interaction:
Although taking metoprolol tartrate and Deriphyllin OD 450 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin OD 450 Tablet:
Coadministration of Nebivolol with Deriphyllin OD 450 Tablet may reduce the effect of Nebivolol.

How to manage the interaction:
Taking Nebivolol with Deriphyllin OD 450 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin OD 450 Tablet:
Co-administration of Deriphyllin OD 450 Tablet with bupropion can increase the risk of seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Deriphyllin OD 450 Tablet can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any symptoms like Temporary confusion, A state of staring, Uncontrollable jerking movements of the arms and legs, Consciousness or awareness loss, Changes in cognition or emotion, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ETOFYLLINE-346MG+THEOPHYLLINE-104MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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ETOFYLLINE-346MG+THEOPHYLLINE-104MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Consumption of caffeine-containing foods/drinks while on the treatment with Theophylline, Etofylline nicotinate can increase the risk of Theophylline, Etofylline nicotinate and cause nausea, vomiting, headache, loose stools, sleeplessness, shaking of hands and legs, fits, restlessness, increased or decreased heartbeat, or difficulty in breathing. Avoid or limit consumption of caffeine-containing foods/drinks while on the treatment with Theophylline, Etofylline nicotinate.

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