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Dexona Tablet is used to treat inflammatory conditions such as allergic disorders and skin conditions. It is also used to treat ulcerative colitis, arthritis, lupus, psoriasis and breathing disorders. Furthermore, it is approved for the treatment of coronavirus disease 2019 (COVID-19) in adult and adolescent patients (aged 12 years and older with a body weight of at least 40 kg) who require supplemental oxygen therapy. It contains Dexamethasone, which works by blocking the release of substances that cause inflammation. Some people may experience side effects like weight gain, indigestion, headache, dizziness, rash, fluid retention (swelling in your hands or ankles), sleep problems, mild mood changes and nausea. Inform the doctor if you have an infection that affects the whole body or if you need to have a vaccination, particularly live virus vaccines.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions: Dexona Tablet may interact with nonsteroidal anti-inflammatory drugs (e.g. aspirin), anticonvulsants (e.g. phenytoin), sedative-hypnotic medications (e.g. phenobarbital, primidone), antibiotics (e.g. rifampicin, rifabutin), anticancer (e.g. aminoglutethimide, methotrexate), anticoagulant (e.g. warfarin), antiretroviral drugs (e.g. ritonavir, darunavir, indinavir), and medicines used to treat epilepsy, pain and manic depression (e.g. carbamazepine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: If you ever had fungal infections, epilepsy, schizophrenia, amoebiasis, myasthenia gravis, peptic ulcer, osteoporosis, psychoses, eye infections, glaucoma, mental conditions, diabetes, TB, bacteraemia (viable bacteria in the bloodstream), joint, liver, kidney, or heart conditions and septic arthritis resulting from gonorrhoea or tuberculosis or have or had a recent vaccination inform your doctor before taking Dexona Tablet .

Drug-Drug Interactions

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How does the drug interact with Dexona Tablet:
When Dexona Tablet is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine and Dexona Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexona Tablet:
When Regorafenib is taken with Dexona Tablet, may significantly reduce the blood levels of Regorafenib.

How to manage the interaction:
Co-administration of Regorafenib and Dexona Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexona Tablet:
Co-administration of Desmopressin with Dexona Tablet may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Dexona Tablet and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DexamethasoneRilpivirine
Critical
How does the drug interact with Dexona Tablet:
When Rilpivirine is taken with Dexona Tablet, may significantly reduce the blood levels of Rilpivirine.

How to manage the interaction:
Co-administration of Rilpivirine and Dexona Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexona Tablet:
When Etanercept is used with Dexona Tablet, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Etanercept and Dexona Tablet, you can take these medicines together if prescribed by a doctor. However, If you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Dexona Tablet:
Taking Dexona Tablet may reduce the blood levels of Axitinib, making the medication less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction, Dexona Tablet can be taken with axitinib if prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
DexamethasoneToremifene
Severe
How does the drug interact with Dexona Tablet:
When Toremifene is taken with Dexona Tablet, may reduce the effectiveness of Toremifene.

How to manage the interaction:
There may be a possibility of interaction between Dexona Tablet and Toremifene, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dexona Tablet:
Taking Cladribine with Dexona Tablet can increase the chances of serious infections.

How to manage the interaction:
Although there is a possible interaction between Cladribine and Dexona Tablet, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexona Tablet:
Dexona Tablet and Ofloxacin co-administration can result in tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture.

How to manage the interaction:
Taking Ofloxacin with Dexona Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dexona Tablet:
Taking Dexona Tablet may lower the blood levels of Sunitinib in some patients, making the medication less effective.

How to manage the interaction:
Although there is a possible interaction, Dexona Tablet can be taken with Sunitinib if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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DEXAMETHASONE-0.5MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEXAMETHASONE-0.5MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Avoid taking caffeine while taking Dexona Tablet. Avoid taking caffeine while taking Dexona Tablet.

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