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Digon 0.25 mg Tablet is used to treat irregular heartbeats and manage the symptoms of heart failure. It contains Digoxin, which works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats. Some people may experience common side effects like diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat or skin rash. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interaction: Digon 0.25 mg Tablet may have interaction with medicines used to treat irregular heartbeat (adenosine, amiodarone, dolasetron, quinidine), cardiac stimulants (arbutamine), HIV/AIDS drugs (atazanavir, saquinavir), anticancer drugs (ceritinib, lapatinib), antibiotics (clarithromycin), immunosuppressants (fingolimod), antidepressants (flibanserin), antifungal drugs (itraconazole) and calcium supplements (calcium chloride, calcium gluceptate, calcium gluconate).

Drug- Food Interaction: Digon 0.25 mg Tablet may interact with alcohol. Therefore, avoid alcohol intake while taking Digon 0.25 mg Tablet .

Drug-Disease Interaction: If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (inability to absorb minerals from food), thyroid disease, or any lung or kidney disease, please inform your doctor before taking Digon 0.25 mg Tablet .

DigoxinSaquinavir
Severe

Drug-Drug Interactions

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How does the drug interact with Digon 0.25 mg Tablet:
Co-administration of Digon 0.25 mg Tablet and Glycopyrronium bromide may increase the serum concentration of Digon 0.25 mg Tablet and increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Digon 0.25 mg Tablet and Glycopyrronium bromide, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, and fast or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DigoxinSaquinavir
Severe
How does the drug interact with Digon 0.25 mg Tablet:
Co-administration of Digon 0.25 mg Tablet and Saquinavir may increase the risk of severe irregular heart rhythm.

How to manage the interaction:
If you are supposed to take Digon 0.25 mg Tablet and Saquinavir together, a doctor may adjust the dose or monitor more frequently to safely use both medications. However, if you develop lightheadedness, fainting, sudden dizziness, nausea, vomiting, loss of appetite, slow pulse, vision disturbances, or irregular heartbeat during treatment with these medications. Contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digon 0.25 mg Tablet:
Co-administration of Calcium gluconate with Digon 0.25 mg Tablet may affect heart rhythm.

How to manage the interaction:
Although there is an interaction, Calcium gluconate can be taken with Digon 0.25 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of irregular heartbeat, blurred vision, chest tightness, nausea, and seizures. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digon 0.25 mg Tablet:
Co-administration of Clarithromycin with Digon 0.25 mg Tablet may increase the blood levels and effects of Digon 0.25 mg Tablet.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Digon 0.25 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of excessive Digon 0.25 mg Tablet levels such as diarrhea, nausea, loss of appetite, vomiting, visual disturbances, and an abnormally fast or slow or uneven heartbeat. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digon 0.25 mg Tablet:
Co-administration of Digon 0.25 mg Tablet and Famotidine may increase the level or effect of Digon 0.25 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Digon 0.25 mg Tablet and Famotidine, you can take these medicines together if prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digon 0.25 mg Tablet:
Co-administration of Calcium carbonate and Digon 0.25 mg Tablet may increase the calcium levels may increase the effects of Digon 0.25 mg Tablet

How to manage the interaction:
Although there is an interaction, Calcium carbonate can be taken with Digon 0.25 mg Tablet if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digon 0.25 mg Tablet:
Coadministration of Digon 0.25 mg Tablet and Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Digon 0.25 mg Tablet and Atazanavir, you can take these medicines together if prescribed by a doctor. However, if you develop fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digon 0.25 mg Tablet:
Co-administration of Amiodarone with Digon 0.25 mg Tablet can increase Digon 0.25 mg Tablet levels which can lead to severe side effects.

How to manage the interaction:
Taking Amiodarone with Digon 0.25 mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, visual disturbances, slow pulse, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
DigoxinTelaprevir
Severe
How does the drug interact with Digon 0.25 mg Tablet:
Co-administration of Digon 0.25 mg Tablet with Telaprevir may increase the blood levels and effects of Digon 0.25 mg Tablet.

How to manage the interaction:
Although taking Telaprevir and Digon 0.25 mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, as these may be signs and symptoms of excessive Digon 0.25 mg Tablet levels. Do not stop using any medications without a doctor's advice.
DigoxinBretylium tosilate
Severe
How does the drug interact with Digon 0.25 mg Tablet:
Co-administration of Digon 0.25 mg Tablet and Bretylium tosilate may increase the effect of Digon 0.25 mg Tablet.

How to manage the interaction:
Although taking Bretylium tosilate and Digon 0.25 mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling sick, throwing up, having seizures, feeling tired, or noticing your heart beating too fast or too slow, it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Digon 0.25 mg Tablet with Grapefruit and Grapefruit juice may increase the side effects of Digon 0.25 mg Tablet. Consuming Grapefruit and grapefruit juice should be avoided while taking Digon 0.25 mg Tablet.

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