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  3. Es-Pitant 80 mg/125 mg Capsule Kit 1's

Es-Pitant 80 mg/125 mg Capsule Kit 1's, Pack of 1
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Es-Pitant 80 mg/125 mg Capsule Kit 1's is used to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. It contains Aprepitant, which blocks a chemical that produces vomiting by acting on the neurological system. Thus, it helps prevent nausea and vomiting.

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Side effects of Es-pitant Kit 80mg/125mg Cap 3's (combipack)
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Drug-Drug Interactions

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AprepitantCisapride
Critical
AprepitantFlibanserin
Critical

Drug-Drug Interactions

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AprepitantCisapride
Critical
How does the drug interact with Es-pitant Kit 80mg/125mg Cap 3's (combipack):
Co-administration with Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Cisapride may cause irregular heart rhythm.

How to manage the interaction:
Although taking Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Cisapride together is not recommended as it can lead to an interaction, it is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
AprepitantFlibanserin
Critical
How does the drug interact with Es-pitant Kit 80mg/125mg Cap 3's (combipack):
Using flibanserin together with Es-pitant Kit 80mg/125mg Cap 3's (combipack) can significantly increase the blood levels of flibanserin.

How to manage the interaction:
Taking Flibanserin and Es-pitant Kit 80mg/125mg Cap 3's (combipack) together is not recommended as it can lead to an interaction; they can be taken if prescribed by a doctor. Consult a doctor if you develop any symptoms, such as extreme sleepiness or low blood pressure, that cause dizziness, lightheadedness, or fainting. To reduce the chance of these side effects, use Flibanserin at bedtime. Do not discontinue any medications without consulting a doctor.
AprepitantEliglustat
Critical
How does the drug interact with Es-pitant Kit 80mg/125mg Cap 3's (combipack):
Es-pitant Kit 80mg/125mg Cap 3's (combipack) combined with Eliglustat can considerably raise blood levels of Eliglustat. This raises the possibility of cardiac adverse effects such as abnormal heart rhythm, heart block, and cardiac arrest.

How to manage the interaction:
Taking Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Eliglustat together is not recommended as it can lead to an interaction; they can be consumed if prescribed by a doctor. Consult a doctor if you have symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, weak heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AprepitantAstemizole
Critical
How does the drug interact with Es-pitant Kit 80mg/125mg Cap 3's (combipack):
Co-administration with Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Astemizole may increase the blood levels of Astemizole.

How to manage the interaction:
Although taking Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Astemizole together is not recommended as it can lead to an interaction, it is safe if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor. Astemizole should not be combined with any other medications without a doctor's advice.
AprepitantTerfenadine
Critical
How does the drug interact with Es-pitant Kit 80mg/125mg Cap 3's (combipack):
Co-administration with Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Terfenadine may increase the blood levels of Terfenadine and leads to irregular heartbeat.

How to manage the interaction:
Taking Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Terfenadine together is not recommended as it can lead to an interaction. It is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
AprepitantPimozide
Critical
How does the drug interact with Es-pitant Kit 80mg/125mg Cap 3's (combipack):
Using pimozide together with Es-pitant Kit 80mg/125mg Cap 3's (combipack) may significantly increase the blood levels of pimozide. High blood levels of pimozide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Pimozide together is not recommended; as it can lead to an interaction, you can take them if your doctor advises you to. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, get immediate medical help. Do not discontinue any medications without consulting a doctor.
AprepitantLomitapide
Critical
How does the drug interact with Es-pitant Kit 80mg/125mg Cap 3's (combipack):
Lomitapide blood levels can be significantly increased by combining it with Es-pitant Kit 80mg/125mg Cap 3's (combipack).

How to manage the interaction:
Although using Lomitapide and Es-pitant Kit 80mg/125mg Cap 3's (combipack) together may cause an interaction, they can be taken if advised by a doctor. Consult a doctor if you have any of the following symptoms: diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, liver problems causing fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AprepitantIvabradine
Severe
How does the drug interact with Es-pitant Kit 80mg/125mg Cap 3's (combipack):
Co-administartion of Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Ivabradine may significantly increase the blood levels of Ivabradine which can result in excessive slowing of heart rate or other side effects.

How to manage the interaction:
Although there is an interaction between Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Ivabradine, it can be taken if prescribed by a doctor. If you have dizziness, tiredness, low blood pressure, heart palpitations, chest pain, or worsening shortness of breath, you should see a doctor. Without consulting a doctor, never stop taking medicines.
AprepitantIbrutinib
Severe
How does the drug interact with Es-pitant Kit 80mg/125mg Cap 3's (combipack):
Co-administration of Ibrutinib together with Es-pitant Kit 80mg/125mg Cap 3's (combipack) may significantly increase the blood levels of Ibrutinib.

How to manage the interaction:
Even though there is an interaction between Es-pitant Kit 80mg/125mg Cap 3's (combipack) and Ibrutinib, it can be taken if a doctor prescribes it. However, doctor if you experience any of the following symptoms: paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in the phlegm, red or inflamed skin, body sores, increased or decreased urination, pain while urinating, nausea, vomiting or loss of hunger, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
AprepitantCilostazol
Severe
How does the drug interact with Es-pitant Kit 80mg/125mg Cap 3's (combipack):
Co-administration of Es-pitant Kit 80mg/125mg Cap 3's (combipack) with cilostazol may increase the risk of side effects.

How to manage the interaction:
Although taking Es-pitant Kit 80mg/125mg Cap 3's (combipack) with cilostazol may cause an interaction, it is safe to do so if advised by your doctor. If you feel dizziness, lightheadedness, fainting, nausea, diarrhea, bleeding, palpitations, or an abnormal heartbeat, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:10 AM IST

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