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Drug-Drug Interactions
Critical
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Grafotas-50 Capsule:
Coadministration of pitavastatin with Grafotas-50 Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Pitavastatin with Grafotas-50 Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
Coadministration of pitavastatin with Grafotas-50 Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Pitavastatin with Grafotas-50 Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
Critical
How does the drug interact with Grafotas-50 Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.
How to manage the interaction:
Taking Grafotas-50 Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
Taking cyclosporine with cidofovir can increase the risk of kidney problems.
How to manage the interaction:
Taking Grafotas-50 Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
Critical
How does the drug interact with Grafotas-50 Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.
How to manage the interaction:
Taking Grafotas-50 Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.
How to manage the interaction:
Taking Grafotas-50 Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Grafotas-50 Capsule:
Combining Grafotas-50 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Grafotas-50 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Combining Grafotas-50 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Grafotas-50 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Critical
How does the drug interact with Grafotas-50 Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.
How to manage the interaction:
Taking Grafotas-50 Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.
How to manage the interaction:
Taking Grafotas-50 Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinSimeprevir
Severe
How does the drug interact with Grafotas-50 Capsule:
Co-administration of simeprevir with Grafotas-50 Capsule may significantly increase the blood levels of simeprevir. This may increase the risk of serious side effects.
How to manage the interaction:
There may be a possibility of interaction between simeprevir and Grafotas-50 Capsule, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Co-administration of simeprevir with Grafotas-50 Capsule may significantly increase the blood levels of simeprevir. This may increase the risk of serious side effects.
How to manage the interaction:
There may be a possibility of interaction between simeprevir and Grafotas-50 Capsule, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Grafotas-50 Capsule:
Taking everolimus with cyclosporine may significantly increases the blood levels of everolimus.
How to manage the interaction:
Although taking everolimus and Grafotas-50 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. In case you experience any side effects like persistent cough, fever, chills, mouth ulcers, paleness of skin, or unusual bleeding or bruising, or blood in stools or urine, consult a doctor. Do not stop using any medications without talking to a doctor.
Taking everolimus with cyclosporine may significantly increases the blood levels of everolimus.
How to manage the interaction:
Although taking everolimus and Grafotas-50 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. In case you experience any side effects like persistent cough, fever, chills, mouth ulcers, paleness of skin, or unusual bleeding or bruising, or blood in stools or urine, consult a doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Grafotas-50 Capsule:
Taking Grafotas-50 Capsule with ritonavir may significantly increases the blood levels of Grafotas-50 Capsule.
How to manage the interaction:
Taking ritonavir with Grafotas-50 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loose stools, abdominal pain, dizziness, weakness, headache, fits, shaking, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination, contact a doctor. Do not stop using any medications without talking to a doctor.
Taking Grafotas-50 Capsule with ritonavir may significantly increases the blood levels of Grafotas-50 Capsule.
How to manage the interaction:
Taking ritonavir with Grafotas-50 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loose stools, abdominal pain, dizziness, weakness, headache, fits, shaking, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination, contact a doctor. Do not stop using any medications without talking to a doctor.
CiclosporinSulfamethizole
Severe
How does the drug interact with Grafotas-50 Capsule:
Coadministration of sulfamethizole with Grafotas-50 Capsule may increases the risk of kidney problems.
How to manage the interaction:
Although there is a possible interaction between sulfamethizole and Grafotas-50 Capsule, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of sulfamethizole with Grafotas-50 Capsule may increases the risk of kidney problems.
How to manage the interaction:
Although there is a possible interaction between sulfamethizole and Grafotas-50 Capsule, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Grafotas-50 Capsule:
Co-administration of ketoconazole with Grafotas-50 Capsule may increases the blood levels of Grafotas-50 Capsule.
How to manage the interaction:
Although taking ketoconazole and Grafotas-50 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if your condition worsens or you encounter more adverse effects, such as nausea, vomiting, diarrhea, abdominal discomfort, exhaustion, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, or increased or decreased urine, consult a doctor. Do not discontinue any medication without consulting a doctor.
Co-administration of ketoconazole with Grafotas-50 Capsule may increases the blood levels of Grafotas-50 Capsule.
How to manage the interaction:
Although taking ketoconazole and Grafotas-50 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if your condition worsens or you encounter more adverse effects, such as nausea, vomiting, diarrhea, abdominal discomfort, exhaustion, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, or increased or decreased urine, consult a doctor. Do not discontinue any medication without consulting a doctor.
Drug-Food Interactions
CYCLOSPORINE-50MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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CYCLOSPORINE-50MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit
How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Grafotas-50 Capsule can increase the effects of Grafotas-50 Capsule. Avoid consuming grapefruit and grapefruit juice while taking Grafotas-50 Capsule.
Grapefruit Juice, Grapefruit
How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Grafotas-50 Capsule can increase the effects of Grafotas-50 Capsule. Avoid consuming grapefruit and grapefruit juice while taking Grafotas-50 Capsule.
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