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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Grandem Syrup is used to prevent nausea and vomiting caused by chemotherapy or radiation therapy in children. It contains Granisetron, which works by blocking a natural substance (serotonin) in the body that causes nausea and vomiting. This medicine may sometimes cause side effects such as diarrhoea, constipation, stomach pain, weakness, headache, fever, dizziness, and drowsiness. Inform your doctor if your child is allergic to Grandem Syrup. Also, let your doctor know your child's complete medication history and medical history before taking Grandem Syrup. This medicine is not recommended for use in pregnant and breastfeeding mothers.

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Drug-Drug Interactions

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GranisetronMesoridazine
Critical

Drug-Drug Interactions

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How does the drug interact with Grandem Syrup 10 ml:
Taking Grandem Syrup 10 ml with Cisapride can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Grandem Syrup 10 ml with Cisapride is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronMesoridazine
Critical
How does the drug interact with Grandem Syrup 10 ml:
Taking Grandem Syrup 10 ml with mesoridazine can increase the risk of an irregular heart rhythm. I

How to manage the interaction:
Taking Mesoridazine with Grandem Syrup 10 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Grandem Syrup 10 ml:
Taking Grandem Syrup 10 ml with Thioridazine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Grandem Syrup 10 ml with Thioridazine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Grandem Syrup 10 ml:
Taking Grandem Syrup 10 ml with Pimozide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Grandem Syrup 10 ml with Pimozide is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Grandem Syrup 10 ml:
Taking Grandem Syrup 10 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Grandem Syrup 10 ml with Ziprasidone is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Grandem Syrup 10 ml:
Taking Grandem Syrup 10 ml with Dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Grandem Syrup 10 ml with Dronedarone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronSaquinavir
Critical
How does the drug interact with Grandem Syrup 10 ml:
When Grandem Syrup 10 ml is taken with Saquinavir, can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Grandem Syrup 10 ml with Saquinavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Grandem Syrup 10 ml:
Taking Grandem Syrup 10 ml with Sparfloxacin can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Grandem Syrup 10 ml with Sparfloxacin is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Grandem Syrup 10 ml:
Coadministration of Grandem Syrup 10 ml with amiodarone may increase the risk of abnormal cardiac rhythms.

How to manage the interaction:
Although taking Grandem Syrup 10 ml with amiodarone may cause an interaction, it is safe to do so if a doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor. Do not stop taking any medications without visiting a doctor.
How does the drug interact with Grandem Syrup 10 ml:
When Vilazodone is taken with Grandem Syrup 10 ml, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
Co-administration of Grandem Syrup 10 ml with Vilazodone can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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