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संघटन :
ओलापैरिब-150MG
निर्माता/विपणक :
एस्ट्रा ज़ेनेका फार्मा इंडिया लिमिटेड
उपभोग प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
को या उसके बाद समाप्त हो जाएगा :
Jan-27
Have a query?
Drug-Drug Interactions
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Lynparza 150 mg Tablet:
When Lynparza 150 mg Tablet is taken with Nevirapine may reduce the blood levels of Lynparza 150 mg Tablet. This can lead to low treatment outcomes.
How to manage the interaction:
There may be a possibility of interaction between Nevirapine and Lynparza 150 mg Tablet, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting a doctor.
When Lynparza 150 mg Tablet is taken with Nevirapine may reduce the blood levels of Lynparza 150 mg Tablet. This can lead to low treatment outcomes.
How to manage the interaction:
There may be a possibility of interaction between Nevirapine and Lynparza 150 mg Tablet, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting a doctor.
How does the drug interact with Lynparza 150 mg Tablet:
Taking Rifabutin and Lynparza 150 mg Tablet may significantly reduce the blood levels of Lynparza 150 mg Tablet, which may make the medication less effective.
How to manage the interaction:
Although taking Lynparza 150 mg Tablet and Rifabutin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Rifabutin and Lynparza 150 mg Tablet may significantly reduce the blood levels of Lynparza 150 mg Tablet, which may make the medication less effective.
How to manage the interaction:
Although taking Lynparza 150 mg Tablet and Rifabutin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlaparibMibefradil
Severe
How does the drug interact with Lynparza 150 mg Tablet:
Using Mibefradil and Lynparza 150 mg Tablet can increase the blood levels of Lynparza 150 mg Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Mibefradil and Lynparza 150 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
Using Mibefradil and Lynparza 150 mg Tablet can increase the blood levels of Lynparza 150 mg Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Mibefradil and Lynparza 150 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Lynparza 150 mg Tablet:
Combining Lynparza 150 mg Tablet with Modafinil may significantly reduce the blood levels of Lynparza 150 mg Tablet. This can lead to low treatment outcomes.
How to manage the interaction:
There may be a possibility of interaction between Lynparza 150 mg Tablet and Modafinil, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Combining Lynparza 150 mg Tablet with Modafinil may significantly reduce the blood levels of Lynparza 150 mg Tablet. This can lead to low treatment outcomes.
How to manage the interaction:
There may be a possibility of interaction between Lynparza 150 mg Tablet and Modafinil, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lynparza 150 mg Tablet:
Coadministration of Phenytoin and Lynparza 150 mg Tablet may decrease the blood levels of Lynparza 150 mg Tablet, which may make Lynparza 150 mg Tablet less effective.
How to manage the interaction:
Although taking Phenytoin and Lynparza 150 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
Coadministration of Phenytoin and Lynparza 150 mg Tablet may decrease the blood levels of Lynparza 150 mg Tablet, which may make Lynparza 150 mg Tablet less effective.
How to manage the interaction:
Although taking Phenytoin and Lynparza 150 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
OlaparibBoceprevir
Severe
How does the drug interact with Lynparza 150 mg Tablet:
Using Boceprevir and Lynparza 150 mg Tablet can increase the blood levels of Lynparza 150 mg Tablet.This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Boceprevir and Lynparza 150 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
Using Boceprevir and Lynparza 150 mg Tablet can increase the blood levels of Lynparza 150 mg Tablet.This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Boceprevir and Lynparza 150 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
OlaparibBCG vaccine
Severe
How does the drug interact with Lynparza 150 mg Tablet:
Combining BCG vaccine with Lynparza 150 mg Tablet can increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Lynparza 150 mg Tablet and BCG vaccine, you can take these medicines together if prescribed by your doctor. If you notice any signs of infection, it's important to contact your doctor right away. They can provide the necessary help and treatment to address the issue. Do not discontinue any medications without first consulting your doctor.
Combining BCG vaccine with Lynparza 150 mg Tablet can increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Lynparza 150 mg Tablet and BCG vaccine, you can take these medicines together if prescribed by your doctor. If you notice any signs of infection, it's important to contact your doctor right away. They can provide the necessary help and treatment to address the issue. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Lynparza 150 mg Tablet:
Phenobarbital can drastically lower Lynparza 150 mg Tablet levels in the blood, making the medicine less effective in treating the cancer.
How to manage the interaction:
Although taking phenobarbital and Lynparza 150 mg Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
Phenobarbital can drastically lower Lynparza 150 mg Tablet levels in the blood, making the medicine less effective in treating the cancer.
How to manage the interaction:
Although taking phenobarbital and Lynparza 150 mg Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lynparza 150 mg Tablet:
Using Darunavir and Lynparza 150 mg Tablet can increase the blood levels of Lynparza 150 mg Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Darunavir and Lynparza 150 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
Using Darunavir and Lynparza 150 mg Tablet can increase the blood levels of Lynparza 150 mg Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Darunavir and Lynparza 150 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
OlaparibNafcillin
Severe
How does the drug interact with Lynparza 150 mg Tablet:
Using Nafcillin together with Lynparza 150 mg Tablet can reduce the blood levels of Lynparza 150 mg Tablet.
How to manage the interaction:
Taking Lynparza 150 mg Tablet with Nafcillin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Your doctor can recommend other options that won't cause any problems when taken together. Do not discontinue any medications without first consulting your doctor.
Using Nafcillin together with Lynparza 150 mg Tablet can reduce the blood levels of Lynparza 150 mg Tablet.
How to manage the interaction:
Taking Lynparza 150 mg Tablet with Nafcillin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Your doctor can recommend other options that won't cause any problems when taken together. Do not discontinue any medications without first consulting your doctor.
Drug-Food Interactions
OLAPARIB-150MGGrapefruit and Grapefruit Juice
Severe
Drug-Food Interactions
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OLAPARIB-150MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Lynparza 150 mg Tablet levels in the blood may rise if it is consumed with grapefruit juice. This may increase possibility of side effects include nausea, vomiting, diarrhea, indigestion, appetite loss, abdominal pain or discomfort. Avoid the consumption of grapefruit juice along with Lynparza 150 mg Tablet. If you’re experiencing nausea, vomiting, diarrhea, indigestion, appetite loss, abdominal pain or discomfort, contact the doctor immediately.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Lynparza 150 mg Tablet levels in the blood may rise if it is consumed with grapefruit juice. This may increase possibility of side effects include nausea, vomiting, diarrhea, indigestion, appetite loss, abdominal pain or discomfort. Avoid the consumption of grapefruit juice along with Lynparza 150 mg Tablet. If you’re experiencing nausea, vomiting, diarrhea, indigestion, appetite loss, abdominal pain or discomfort, contact the doctor immediately.
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शराब
Caution
लिनपार्ज़ा 150 मिलीग्राम टैबलेट 8 के साथ उपचार के दौरान शराब के सेवन से बचें।
गर्भावस्था
Unsafe
लिनपार्ज़ा 150 मिलीग्राम टैबलेट 8 का उपयोग गर्भावस्था के दौरान नहीं किया जाना चाहिए क्योंकि यह आपके भ्रूण (नवजात शिशु) को नुकसान पहुंचा सकता है। प्रजनन क्षमता वाली महिलाओं और पुरुषों दोनों को लिनपार्ज़ा 150 मिलीग्राम टैबलेट 8 लेते समय और उपचार के बाद कम से कम छह महीने तक प्रभावी गर्भनिरोधक विधि का उपयोग करना चाहिए। आपका डॉक्टर इस दवा को निर्धारित करने से पहले लाभ और जोखिमों का मूल्यांकन करेगा।
स्तनपान
Unsafe
इस उपचार के दौरान स्तनपान न कराएं क्योंकि दवा आपके दूध में जा सकती है। डॉक्टर आमतौर पर इस उपचार के दौरान और अंतिम दवा लेने के एक महीने बाद तक स्तनपान न कराने की सलाह देते हैं।
ड्राइविंग
Caution
लिनपार्ज़ा 150 मिलीग्राम टैबलेट 8 आपकी प्रतिक्रियाओं और आपकी गाड़ी चलाने की क्षमता को प्रभावित कर सकता है। ऐसी गाड़ी न चलाएं और/या मशीनें न चलाएं जिनके लिए आपकी सतर्कता की आवश्यकता होती है।
जिगर
Caution
हल्के या मध्यम यकृत क्षति वाले रोगियों में, प्रारंभिक खुराक में बदलाव करने की कोई आवश्यकता नहीं है। गंभीर यकृत क्षति वाले रोगियों के बारे में कोई जानकारी उपलब्ध नहीं है।
किडनी
Caution
हल्के या मध्यम किडनी क्षति वाले रोगियों में, प्रारंभिक खुराक में बदलाव करने की कोई आवश्यकता नहीं है। गंभीर किडनी क्षति वाले रोगियों के बारे में कोई जानकारी उपलब्ध नहीं है।
बच्चे
Caution
बाल रोगियों में लिनपार्ज़ा 150 मिलीग्राम टैबलेट 8 की सुरक्षा और प्रभावशीलता स्थापित नहीं की गई है।
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