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Mikacin 1000 mg/4 ml Injection 4 ml is used to treat bacterial infections. It contains Amikacin sulphate, which works by inhibiting the production of bacterial proteins which are necessary for the survival of the bacteria. Thereby, leads to the death of the bacterial cell. Thus, it helps treat bacterial infections. In some cases, you may experience certain common side effects such as irritation at the site of application, skin rash, nausea, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Mikacin 1000 mg/4 ml Injection 4 ml
  • Eat nutrient-rich foods, including carrots, potatoes, fruits, vegetables, and healthy fats.
  • Stay hydrated by drinking plenty of fluids to flush out waste from the body.
  • Exercise regularly for overall wellness.
  • Avoid harmful substances, including excessive alcohol and smoking.
  • Be cautious with medications like ibuprofen, naproxen, and aspirin - consult your doctor before taking them.
  • Seek medical advice to identify and address underlying health issues.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.
  • Drink more fluids as dehydration can decrease blood flow to kidneys and increase BUN levels.
  • Eat less protein and stop protein supplements as high protein diet may increase BUN levels.
  • Severe cases may require kidney transplant or dialysis.

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Drug-Drug Interactions

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Drug-Drug Interactions: Mikacin 1000 mg/4 ml Injection 4 ml may have interaction with water pills/diuretics (furosemide, ethacrynic acid), pain killers (indomethacin, aspirin, lidocaine), antibiotics (like penicillin, kanamycin, gentamycin, ceftriaxone, vancomycin); vitamin supplements (like thiamine), anti-cancer drugs (like cisplatin).

Drug-Food Interactions: No food interactions have been found.

Drug-Disease Interactions: Inform your doctor if you have dehydration, neuromuscular blockade (blockage of the neuromuscular transmission at the junction), ototoxicity (ear toxicity/ear dysfunction) and renal dysfunction (kidney problems).

AmikacinBCG vaccine
Critical

Drug-Drug Interactions

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AmikacinBCG vaccine
Critical
How does the drug interact with Mikacin 1000 mg/4 ml Injection 4 ml:
Coadministration of BCG vaccine with Mikacin 1000 mg/4 ml Injection 4 ml can reduce its effectiveness.

How to manage the interaction:
Taking Mikacin 1000 mg/4 ml Injection 4 ml with the BCG vaccine can result in an interaction. Furthermore, if you have active TB, you should not undergo BCG therapy. However, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mikacin 1000 mg/4 ml Injection 4 ml:
Co-administration of cidofovir with Mikacin 1000 mg/4 ml Injection 4 ml can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Cidofovir with Mikacin 1000 mg/4 ml Injection 4 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, dizziness, or palpitations, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
AmikacinBacitracin
Severe
How does the drug interact with Mikacin 1000 mg/4 ml Injection 4 ml:
Coadministration of Mikacin 1000 mg/4 ml Injection 4 ml with Bacitracin can increase the risk of developing side effects like hearing loss, difficulty breathing, or kidney problems.

How to manage the interaction:
Although taking Mikacin 1000 mg/4 ml Injection 4 ml and bacitracin together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience ringing in the ears, difficulty breathing, vomiting, increased or decreased urination, swelling, muscle cramps, dizziness, or palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mikacin 1000 mg/4 ml Injection 4 ml:
Co-administration of Mikacin 1000 mg/4 ml Injection 4 ml with Atracurium can increase the risk of developing breathing difficulties.

How to manage the interaction:
Taking Atracurium with Mikacin 1000 mg/4 ml Injection 4 ml together can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor if you experience shortness of breath, palpitations, chest discomfort, or dizziness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mikacin 1000 mg/4 ml Injection 4 ml:
Coadministration of Mikacin 1000 mg/4 ml Injection 4 ml and Everolimus can increase the risk of developing kidney problems.

How to manage the interaction:
Although taking Mikacin 1000 mg/4 ml Injection 4 ml and Everolimus together can result in an interaction, it can be taken if a doctor has prescribed it. Consult the doctor if you experience vomiting, increased or decreased urination, swelling, shortness of breath, muscle cramps, weakness, or palpitation. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mikacin 1000 mg/4 ml Injection 4 ml:
Taking Human immunoglobulin with Mikacin 1000 mg/4 ml Injection 4 ml, may raise the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Mikacin 1000 mg/4 ml Injection 4 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, weakness, or palpitation, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mikacin 1000 mg/4 ml Injection 4 ml:
Coadministration of Sirolimus with Mikacin 1000 mg/4 ml Injection 4 ml can increase the risk of kidney problems.

How to manage the interaction:
Although taking Mikacin 1000 mg/4 ml Injection 4 ml and sirolimus together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience vomiting, irregular urination, swelling, difficulty breathing, muscle pain, weakness, or palpitation, consult a doctor. Do not discontinue any medications without a doctor's advice.
AmikacinEtacrynic acid
Severe
How does the drug interact with Mikacin 1000 mg/4 ml Injection 4 ml:
Coadministration of Mikacin 1000 mg/4 ml Injection 4 ml with Ethacrynic acid can increase the risk of developing side effects. Elderly patients, those who are dehydrated, and patients with a history of kidney problems are at greater risk.

How to manage the interaction:
Although taking Etacrynic acid and Mikacin 1000 mg/4 ml Injection 4 ml together can cause an interaction, it can be taken if your doctor has suggested it. Consult a doctor if you experience decreased urination, vomting, shortness of breath, blurred vision, or muscle cramps. Do not stop using any medications without a doctor's advice.
How does the drug interact with Mikacin 1000 mg/4 ml Injection 4 ml:
Coadministration of Mikacin 1000 mg/4 ml Injection 4 ml and Capreomycin can increase the risk of side effects. Elderly patients, or patients who have a history of kidney problems may be at a higher risk.

How to manage the interaction:
Although taking Mikacin 1000 mg/4 ml Injection 4 ml and Capreomycin together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience difficulty breathing, vomiting, irregular urination, sudden weight gain or loss, swelling, muscle cramps, dizziness, or palpitations. Do not discontinue any medications without consulting a doctor.
AmikacinBumetanide
Severe
How does the drug interact with Mikacin 1000 mg/4 ml Injection 4 ml:
Coadministration of Mikacin 1000 mg/4 ml Injection 4 ml with Bumetanide can cause side effects like kidney problems. Patients who are dehydrated or with a history of kidney problems are at a higher risk.

How to manage the interaction:
Although taking Mikacin 1000 mg/4 ml Injection 4 ml and bumetanide together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience ringing in the ears, irregular urination, vomting, or muscle cramps, consult the doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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