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ONDAMAC MD TABLET
ONDAMAC MD TABLET
ONDAMAC MD TABLET

ONDAMAC MD TABLET is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment, or surgery. It contains ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. It may cause common side effects such as constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. Before taking this medication, inform your doctor if you are allergic to any of its components.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ONDANSETRON-4MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About ONDAMAC MD TABLET

ONDAMAC MD TABLET is primarily used in the prevention of vomiting and nausea. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response of the body to expel the stomach contents from the mouth forcefully.

ONDAMAC MD TABLET contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.

You may experience common side effects such as constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. If the side effects persist or worsen, please consult your doctor.

Before using ONDAMAC MD TABLET, inform your doctor if you are allergic to any of its ingredients. ONDAMAC MD TABLET should be used during pregnancy and breastfeeding only if prescribed by a doctor.

Uses of ONDAMAC MD TABLET

ONDAMAC MD TABLET is used in the prevention of Nausea and Vomiting. The detailed uses of ONDAMAC MD TABLET are as follows:

  • Chemotherapy-Induced Nausea and Vomiting: ONDAMAC MD TABLET is frequently prescribed to alleviate nausea and vomiting caused by chemotherapy treatments.
  • Radiation Therapy Support: ONDAMAC MD TABLET can help manage nausea and vomiting experienced by patients undergoing radiation therapy, improving treatment tolerance.
  • Postoperative Nausea and Vomiting Relief: Many patients experience nausea or vomiting after surgical procedures, and ONDAMAC MD TABLET is effective in controlling and reducing these symptoms.

Have a query?

Directions for Use

  • ONDAMAC MD TABLET can be taken with or without food, as advised by the doctor.
  • Typically, it is taken twice daily. However, follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow the tablet as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Key Benefits

  • ONDAMAC MD TABLET is an antiemetic medication primarily used to prevent and treat nausea and vomiting associated with conditions such as cancer chemotherapy, radiation treatment, and surgery.
  • When serotonin levels increase in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain, which is responsible for controlling nausea and vomiting.
  • ONDAMAC MD TABLET contains Ondansetron, which works by inhibiting the release of serotonin, thereby preventing nausea and vomiting.

How ONDAMAC MD TABLET Works

ONDAMAC MD TABLET contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, ONDAMAC MD TABLET prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy, or motion sickness.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ondamac Md Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Avoid rubbing or scratching the affected area, as this can cause further irritation and discomfort.
  • Consider using a humidifier to add moisture to the air and help reduce the sensation.
  • Seek medical attention if the sensation is severe, persistent, or worsens over time.
  • Avoid extreme temperatures, such as hot or cold showers, that can exacerbate the sensation.
  • Wear light, breathable clothing to help keep the body cool and reduce the sensation.
  • Avoid triggers that can cause the sensation, such as spicy foods or hot drinks.
  • Use cool compresses or fans to help lower body temperature and reduce the sensation.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of ONDAMAC MD TABLET

Do not take more than the prescribed dose of ONDAMAC MD TABLET, as it may lead to an overdose. Symptoms of an overdose may include sudden loss of vision for a short time, irregular heartbeat, constipation, fainting, dizziness, or light-headedness. If you suspect that you have taken an overdose of this medication or notice any unusual symptoms, please consult a doctor immediately.

Drug Warnings

  • Do not use ONDAMAC MD TABLET if you are allergic to any of its ingredients.
  • Avoid using ONDAMAC MD TABLET if you are taking apomorphine (a medicine used to treat Parkinson's disease), as it may cause a sharp drop in blood pressure and even fainting.
  • Inform your doctor before using ONDAMAC MD TABLET if you have any medical conditions, such as severe constipation, bowel obstruction, depression, electrolyte imbalance, heart or blood vessel problems (such as irregular heartbeats and high blood pressure), diabetes, liver problems, or a history of tonsils or adenoid removal surgery.
  • Tell your doctor if you are taking any medications for depression, as using them alongside ONDAMAC MD TABLET may increase the risk of serotonin syndrome, a potentially life-threatening condition.
  • ONDAMAC MD TABLET is not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.
  • Avoid breastfeeding while taking ONDAMAC MD TABLET, as small amounts of the medicine may pass into breast milk.
  • Avoid consuming alcohol while taking ONDAMAC MD TABLET, as it may worsen the side effects like drowsiness.

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronTapentadol
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Ondamac Md Tablet:
Taking Ondamac Md Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ondamac Md Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronTapentadol
Severe
How does the drug interact with Ondamac Md Tablet:
Using Tapentadol together with Ondamac Md Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although taking Ondamac Md Tablet along with tapentadol can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronAnagrelide
Severe
How does the drug interact with Ondamac Md Tablet:
Taking Ondamac Md Tablet with anagrelide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondamac Md Tablet alongside anagrelide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
OndansetronMethadone
Severe
How does the drug interact with Ondamac Md Tablet:
Taking Ondamac Md Tablet with methadone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondamac Md Tablet along with methadone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronToremifene
Severe
How does the drug interact with Ondamac Md Tablet:
Taking Ondamac Md Tablet with toremifene increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Ondamac Md Tablet along with toremifene can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronCabozantinib
Severe
How does the drug interact with Ondamac Md Tablet:
Taking Ondamac Md Tablet with cabozantinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondamac Md Tablet along with cabozantinib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
OndansetronAmiodarone
Severe
How does the drug interact with Ondamac Md Tablet:
Coadministration of Ondamac Md Tablet with amiodarone can lead to or increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ondamac Md Tablet with amiodarone together can result in interaction, it should be taken only if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without a doctor's advice.
OndansetronAlmotriptan
Severe
How does the drug interact with Ondamac Md Tablet:
When Ondamac Md Tablet, is taken with almotriptan it can cause serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Ondamac Md Tablet along with almotriptan can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronHaloperidol
Severe
How does the drug interact with Ondamac Md Tablet:
Co-administration of Ondamac Md Tablet with haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Ondamac Md Tablet along with haloperidol can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronSertraline
Severe
How does the drug interact with Ondamac Md Tablet:
Co-administration of Sertraline and Ondamac Md Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body) and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Ondamac Md Tablet along with Sertraline can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, diarrhea, dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, while taking these medications. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small meals throughout the day and eat slowly to help digestion.
  • If you are sensitive to food smells, try eating cold or room-temperature foods instead of hot ones.
  • Avoid acidic foods or drinks like orange or grapefruit juice.
  • After your meals, rest with your head elevated about 12 inches above your head.
  • Drink liquids or water between meals rather than during meals.
  • Eat when you are least nauseated to help prevent discomfort.
  • Avoid consuming greasy or oily foods, as these foods can trigger nausea and vomiting.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid makeup that has been lost due to vomiting.

Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

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Alcohol

Caution

Alcohol has no known direct interaction with ONDAMAC MD TABLET. However, it is advisable to avoid consuming alcohol while taking ONDAMAC MD TABLET, as it may worsen the side effects like drowsiness.

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Pregnancy

Unsafe

ONDAMAC MD TABLET should be used during pregnancy only if prescribed by a doctor. It is generally not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking ONDAMAC MD TABLET, as small amounts of the medicine may pass into breast milk.

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Driving

Caution

ONDAMAC MD TABLET does not affect your ability to drive. However, if you experience drowsiness or blurred vision after taking ONDAMAC MD TABLET, avoid driving or operating any heavy machinery.

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Liver

Caution

In individuals with liver problems, the use of ONDAMAC MD TABLET is allowed if prescribed by a doctor. However, patients with severe liver impairment should take a low dose of ONDAMAC MD TABLET as much as possible. Do not take more than 8 mg of ONDAMAC MD TABLET per day in case of liver disease.

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Kidney

Safe if prescribed

The use of ONDAMAC MD TABLET is considered safe in patients with kidney disorders. No dose adjustment is required.

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Children

Safe if prescribed

ONDAMAC MD TABLET should not be given to children below 4 years of age, as its safety and effectiveness have not been established in this age group. The use of ONDAMAC MD TABLET is safe in children above 4 years of age if prescribed by a doctor.

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Heart

Caution

ONDAMAC MD TABLET should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using ONDAMAC MD TABLET.

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Geriatrics

Caution

ONDAMAC MD TABLET should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using ONDAMAC MD TABLET.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - OND0035

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Nov 21, 2025 | 11:22 AM IST

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