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Drug-Drug Interactions
Critical
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Pearl Oral Contraceptive Pills:
Taking Pearl Oral Contraceptive Pills with Tranexamic acid may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.
How to manage the interaction:
Taking Tranexamic acid with Pearl Oral Contraceptive Pills may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Pearl Oral Contraceptive Pills with Tranexamic acid may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.
How to manage the interaction:
Taking Tranexamic acid with Pearl Oral Contraceptive Pills may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Pearl Oral Contraceptive Pills:
Coadministration of Acitretin with Pearl Oral Contraceptive Pills can increase the risk and severity of birth defects in unborn when taken by a pregnant woman.
How to manage the interaction:
Taking Acitretin with Pearl Oral Contraceptive Pills together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Never use acitretin if you are pregnant. Do not stop using any medications without talking to a doctor.
Coadministration of Acitretin with Pearl Oral Contraceptive Pills can increase the risk and severity of birth defects in unborn when taken by a pregnant woman.
How to manage the interaction:
Taking Acitretin with Pearl Oral Contraceptive Pills together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Never use acitretin if you are pregnant. Do not stop using any medications without talking to a doctor.
LevonorgestrelEtretinate
Critical
How does the drug interact with Pearl Oral Contraceptive Pills:
Using etretinate and Pearl Oral Contraceptive Pills can cause severe birth defects.
How to manage the interaction:
Taking Etretinate with Pearl Oral Contraceptive Pills can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Using etretinate and Pearl Oral Contraceptive Pills can cause severe birth defects.
How to manage the interaction:
Taking Etretinate with Pearl Oral Contraceptive Pills can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Pearl Oral Contraceptive Pills:
Taking Pearl Oral Contraceptive Pills with Tranexamic acid may increase the risk of blood clot formation.
How to manage the interaction:
Taking Pearl Oral Contraceptive Pills with Tranexamic acid is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Pearl Oral Contraceptive Pills with Tranexamic acid may increase the risk of blood clot formation.
How to manage the interaction:
Taking Pearl Oral Contraceptive Pills with Tranexamic acid is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Using Pearl Oral Contraceptive Pills with tizanidine can result in increased side effects.
How to manage the interaction:
Although taking Pearl Oral Contraceptive Pills and tizanidine together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting, consult the doctor. Do not discontinue any medication without consulting a doctor.
Using Pearl Oral Contraceptive Pills with tizanidine can result in increased side effects.
How to manage the interaction:
Although taking Pearl Oral Contraceptive Pills and tizanidine together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting, consult the doctor. Do not discontinue any medication without consulting a doctor.
LevonorgestrelSugammadex
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Taking Pearl Oral Contraceptive Pills and Sugammadex may reduce the blood levels and effects of Pearl Oral Contraceptive Pills.
How to manage the interaction:
Although there is a possible interaction between Sugammadex and Pearl Oral Contraceptive Pills, you can take these medicines together if prescribed by a doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
Taking Pearl Oral Contraceptive Pills and Sugammadex may reduce the blood levels and effects of Pearl Oral Contraceptive Pills.
How to manage the interaction:
Although there is a possible interaction between Sugammadex and Pearl Oral Contraceptive Pills, you can take these medicines together if prescribed by a doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Taking Pearl Oral Contraceptive Pills and Phenytoin may lower Pearl Oral Contraceptive Pills blood levels and effects.
How to manage the interaction:
Although taking Pearl Oral Contraceptive Pills and phenytoin together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment(Pearl Oral Contraceptive Pills) for menopause, consult the doctor if your experience abnormal bleeding. Do not stop using any medications without talking to a doctor.
Taking Pearl Oral Contraceptive Pills and Phenytoin may lower Pearl Oral Contraceptive Pills blood levels and effects.
How to manage the interaction:
Although taking Pearl Oral Contraceptive Pills and phenytoin together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment(Pearl Oral Contraceptive Pills) for menopause, consult the doctor if your experience abnormal bleeding. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pearl Oral Contraceptive Pills:
Carfilzomib can occasionally cause dangerous blood clots and using it together with Pearl Oral Contraceptive Pills may increase the risk.
How to manage the interaction:
Co-administration of Carfilzomib with Pearl Oral Contraceptive Pills can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: blood clots that can be harmful, high blood pressure or cholesterol, heart problems like heart attack or blockage in the lung, stroke, complications, chest pain, difficulty breathing, coughing up blood, sudden vision loss, pain, redness, or swelling in an arm or leg, and numbness or weakness on one side of your body. Do not discontinue any medications without consulting a doctor.
Carfilzomib can occasionally cause dangerous blood clots and using it together with Pearl Oral Contraceptive Pills may increase the risk.
How to manage the interaction:
Co-administration of Carfilzomib with Pearl Oral Contraceptive Pills can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: blood clots that can be harmful, high blood pressure or cholesterol, heart problems like heart attack or blockage in the lung, stroke, complications, chest pain, difficulty breathing, coughing up blood, sudden vision loss, pain, redness, or swelling in an arm or leg, and numbness or weakness on one side of your body. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Topiramate may lower the blood levels and effects of Pearl Oral Contraceptive Pills, making it less effective as a type of birth control.
How to manage the interaction:
Although taking Pearl Oral Contraceptive Pills and topiramate can lead to an interaction, it can be taken if prescribed by a doctor. If you have been receiving hormone replacement therapy (Pearl Oral Contraceptive Pills) for menopause, you should contact the doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not stop using any medications without talking to a doctor.
Topiramate may lower the blood levels and effects of Pearl Oral Contraceptive Pills, making it less effective as a type of birth control.
How to manage the interaction:
Although taking Pearl Oral Contraceptive Pills and topiramate can lead to an interaction, it can be taken if prescribed by a doctor. If you have been receiving hormone replacement therapy (Pearl Oral Contraceptive Pills) for menopause, you should contact the doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not stop using any medications without talking to a doctor.
LevonorgestrelMycophenolate Mofetil
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Taking Pearl Oral Contraceptive Pills with Mycophenolate mofetil can decrease the levels of Pearl Oral Contraceptive Pills in the body. This increases the risk of severe bleeding and unintended pregnancy.
How to manage the interaction:
Although taking Mycophenolate Mofetil and Pearl Oral Contraceptive Pills together can cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience worsening of your symptoms such as hot flashes, vaginal dryness, or abnormal bleeding. Do not discontinue any medication without consulting a doctor.
Taking Pearl Oral Contraceptive Pills with Mycophenolate mofetil can decrease the levels of Pearl Oral Contraceptive Pills in the body. This increases the risk of severe bleeding and unintended pregnancy.
How to manage the interaction:
Although taking Mycophenolate Mofetil and Pearl Oral Contraceptive Pills together can cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience worsening of your symptoms such as hot flashes, vaginal dryness, or abnormal bleeding. Do not discontinue any medication without consulting a doctor.
Drug-Food Interactions
ETHINYLESTRADIOL-0.03MG+LEVONORGESTREL-0.15MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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ETHINYLESTRADIOL-0.03MG+LEVONORGESTREL-0.15MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Taking Grapefruit or Grapefruit juice while on the treatment with Ethinylestradiol, Levonorgestrel can lead to increase in blood levels of Ethinylestradiol, Levonorgestrel. Avoid or limit the consumption of grapefruit and grapefruit juice during treatment with Ethinylestradiol, Levonorgestrel.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Taking Grapefruit or Grapefruit juice while on the treatment with Ethinylestradiol, Levonorgestrel can lead to increase in blood levels of Ethinylestradiol, Levonorgestrel. Avoid or limit the consumption of grapefruit and grapefruit juice during treatment with Ethinylestradiol, Levonorgestrel.
शराब
असुरक्षित
अप्रिय दुष्प्रभावों से बचने के लिए आपको पर्ल ओरल गर्भनिरोधक गोलियाँ 28's के साथ शराब का सेवन न करने की सलाह दी जाती है।
गर्भावस्था
असुरक्षित
सावधानी बरतनी चाहिए। हार्मोनल दवाएं विकासशील बच्चे को प्रभावित कर सकती हैं। इसका उपयोग करने से पहले डॉक्टर से परामर्श करने की सलाह दी जाती है।
स्तनपान
असुरक्षित
सुरक्षित नहीं; यह पर्ल ओरल गर्भनिरोधक गोलियाँ 28's स्तन के दूध में जा सकता है। वे बच्चे को नुकसान पहुंचा सकते हैं और दूध के उत्पादन को भी प्रभावित कर सकते हैं। इसलिए, स्तनपान कराने वाली माताओं के लिए यह पर्ल ओरल गर्भनिरोधक गोलियाँ 28's असुरक्षित है।
ड्राइविंग
सावधानी
पर्ल ओरल गर्भनिरोधक गोलियाँ 28's का वाहन चलाने या मशीनों का उपयोग करने की क्षमता पर कोई या नगण्य प्रभाव नहीं पड़ता है।
जिगर
सावधानी
पर्ल ओरल गर्भनिरोधक गोलियाँ 28's सावधानी के साथ लेना है, खासकर यदि आपको लीवर की बीमारियों/स्थितियों का इतिहास रहा है। आपके डॉक्टर द्वारा खुराक को समायोजित करना पड़ सकता है।
गुर्दा
सावधानी
पर्ल ओरल गर्भनिरोधक गोलियाँ 28's सावधानी के साथ लेना है, खासकर यदि आपको किडनी की बीमारियों/स्थितियों का इतिहास रहा है। आपके डॉक्टर द्वारा खुराक को समायोजित करना पड़ सकता है।
बच्चे
सावधानी
पर्ल ओरल गर्भनिरोधक गोलियाँ 28's बच्चों के लिए अनुशंसित नहीं है। पर्ल ओरल गर्भनिरोधक गोलियाँ 28's की सुरक्षा और प्रभावकारिता प्रजनन आयु की महिलाओं में स्थापित है। लेकिन 16 साल से कम उम्र की महिलाओं पर पर्याप्त अध्ययन नहीं किए गए हैं। इसलिए, पर्ल ओरल गर्भनिरोधक गोलियाँ 28's तभी लें जब डॉक्टर द्वारा निर्धारित किया गया हो।
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